Clinical trials: Block
Posterior Fossa Tumors
The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery
This study evaluate the effects of scalp block versus local infiltration on haemodynamic response to head pin replacement and skin incision and postoperative analgesia in posterior fossa surgery
- Trial name
- NCT02852382
- Testing
- Bupivacaine, morphine patient controlled analgesia
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Atherosclerosis, Lupus Nephritis
Angiotensin-II Receptor Antibodies Blockade With Losartan in Patients With Lupus Nephritis
Antibodies directed against angiotensin-II receptor (AT1-Ab) are agonist antibodies previously studied in human diseases such as preeclampsia, transplantation and scleroderma.
- Trial name
- NCT03526042
- Testing
- Losartan, Enalapril
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Pain, Post Operative, Regional Anesthesia
Pain Reduction in Maxillomandibular Surgery Using Maxillary and Mandibular Nerve Blocks
Maxillo-mandibular osteotomy is a painful surgery which requires mostly opioids use. Recent studies on maxillary and mandibular nerve blocks have suggested benefit in maxillo-facial surgery but have been poorly investigated in…
- Trial name
- ECHOMAX (NCT05351151)
- Testing
- bilateral ultra-sound guided maxillary and mandibular nerve blocks, Infiltration of Lidocaine 1%
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Feedback
Simulation-based Training for Ultrasound-guided Popliteal Sciatic Nerve Block
The goal of this study is to evaluate whether remote asynchronous feedback is non-inferior to direct synchronous feedback during simulation-based training for ultrasound-guided popliteal sciatic nerve block performance.
- Trial name
- NCT07659145
- Testing
- Asynchronous distance feedback, Synchronous direct feedback
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Microtia, Congenital, Microtia
Rib Microtia and the Erector Spinae Plane (ESP) Block
The erector spinae plane block is a novel regional anesthetic technique that allows for analgesia of the thorax and abdomen with a peripheral nerve block.
- Conditions
- Microtia, Congenital, Microtia, Anesthesia, Local, Anesthesia
- Trial name
- NCT03729427
- Testing
- Erector Spinae Plane Block
- Where
- United States
- Sponsor
- Stanford University
Congenital Nasolacrimal Duct Obstruction
Recanalization of Congenital Nasolacrimal Duct Obstruction by Endodiathermy Probe and Intubation Versus Intubation Only
The purpose of the current work is to assess the efficiency and success rate of endodiathermy probe followed by intubation in children more than 2 years compared to the success rate of intubation (as a standard method) which…
- Trial name
- NCT04148170
- Testing
- Endodiathermy Probe and Intubation Versus Intubation
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Prostate Cancer, Bladder Outlet Obstruction
Prostatic Artery Embolization in Advanced Prostate Cancer
This is a pilot study assessing efficacy and safety in patients with advanced prostate cancer.
- Trial name
- NCT03457805
- Testing
- Prostatic Artery Embolization
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Dominik Abt
Distal Radius Fracture, Forearm Fracture
Ultrasound Guided Axillary Nerve Block Compared to Hematoma Block in Patients With Closed Reposition of Distal Forearm Fractures
Rationale: For distal forearm fractures the investigators propose an anaesthetic method using an ultrasound guided axillary nerve block (ANB, an established technique) for pain reduction during reposition dislocated fractures.
- Trial name
- NCT05674383
- Testing
- Axillary plexus nerve block, Fracture hematoma block
- Where
- Netherlands
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Frisius Medisch Centrum
Other Reconstructive Surgery
Retrospective Femoral Nerve Block Study
This is a retrospective review to evaluate the efficacy of femoral nerve block in providing analgesia following reconstructive surgery of the knee and to compare the postoperative course of patients who received femoral nerve…
- Trial name
- NCT01293136
- Testing
- Femoral nerve block, Intravenous opioids
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Nationwide Children's Hospital
Chronic Kidney Diseases, Bladder Dysfunction
Concomitant Renal and Urinary Bladder Allograft Transplantation
The purpose of this study is to establish if concomitant renal and vascularized urinary bladder allograft transplantation is feasible.
- Conditions
- Chronic Kidney Diseases, Bladder Dysfunction, Bladder Absence, Posterior Urethral Valve
- Trial name
- NCT04626167
- Testing
- Concomitant Renal and Urinary Bladder Allograft Transplantation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Respiratory-Gated Imaging Techniques
Functional Respiratory Imaging After Neostigmine or Sugammadex
The use of neuromuscular blocking agents (NMBAs) is still associated with postoperative pulmonary complications. The investigators rely on acceleromyography (AMG) of a peripheral nerve/muscle to assess the patients' breathing…
- Trial name
- FRINeoS (NCT02284412)
- Testing
- Neostigmine, Sugammadex, Water for injection
- Where
- Belgium
- Volunteers
- 13 people
- Sponsor
- Onze Lieve Vrouw Hospital
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Anesthesia, Hernia, Inguinal
Comparative Study Between US Guided Erector Spinae and US Guided Cudal Epidural Block
Inguinal hernia is a common condition requiring surgical repair in the pediatric age group. The incidence of inguinal hernias is approximately 3% to 5% in term infants and 13% in infants born at less than 33 weeks of gestational…
- Trial name
- NCT07127601
- Testing
- Ultrasound guided erector spinae plain block (ESPB).
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aortic Valve Stenosis
SAPIEN 3 Ultra System PMCF
A post-market study of the Edwards SAPIEN 3 Ultra System in subjects with symptomatic, severe, calcific aortic stenosis.
- Trial name
- NCT04555967
- Testing
- SAPIEN 3 Ultra System
- Where
- 11 sites in Austria, Canada and 6 more
- Volunteers
- 200 people
- Sponsor
- Edwards Lifesciences
Pain, Pain, Postoperative
S-ESP and Ring Block in Circümcision Surgery (S-ESP: Sacral Erectör Spinae Plane Block).
Although it is not known exactly when and where circumcision was first performed, it is claimed that it was first performed by the Egyptians, according to various beliefs and traditions.
- Trial name
- NCT06136000
- Testing
- Sacral erectör spinae plane block, Ring Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Konya City Hospital
Pericapsular Nerve Group Block
Combined Pericapsular Nerve Group Block and Lateral Femoral Cutaneous Nerve Block for Pediatric Hip Surgeries
combined pericapsular nerve group PENG block and lateral femoral cutaneous nerve block may be effective in reducing post-operative pain after open hip surgery in children.
- Trial name
- NCT06417268
- Testing
- Caudal epidural analgesia, Ultrasound-guided Combined Pericapsular Nerve Group Block, Ultrasound-guided Lateral Femoral Cutaneous Nerve Block
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Kasr El Aini Hospital
Cardiac Valve Disease, Aortic Valve Stenosis
Remote ECG Monitoring of TAVI Patients
After surgery, patients who undergo transcatheter aortic valve implantation (TAVI) are at risk of developing cardiac arrhythmias such as heart blocks and atrial fibrillation.
- Trial name
- NCT03810820
- Testing
- mobile Cardiac Arrhythmia Diagnostics Service (m-CARDS)
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Population Health Research Institute
Flexor Tendon Rupture
Comparison Between Functional Outcomes of Flexor Tendon Repair Under WALANT and Brachial Plexus Block
Although outcomes after flexor tendon repair have reportedly improved with modern treatment, complications are common. Early passive and active motion protocols have improved outcomes of flexor tendon repairs.
- Trial name
- NCT06149962
- Testing
- FLEXOR TENDON REPAIR
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Neuroblastoma, Pediatric Solid Tumor
GVAX Plus Checkpoint Blockade in Neuroblastoma
This research clinical trial is studying the creation and administration of GVAX, an irradiated GM-CSF secreting, autologous neuroblastoma cell vaccine (GVAX) in combination with nivolumab and ipilimumab as a possible treatment…
- Trial name
- NCT04239040
- Testing
- Tissue collection, GVAX vaccine, Nivolumab
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- Dana-Farber Cancer Institute
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