Clinical trials: Block
Procedural Pain
A Combined 2% Lidocaine Anesthetic Technique for Mandibular Molar Procedures Without Inferior Alveolar Nerve Block
This prospective single-arm pilot study evaluated the clinical effectiveness of a combined local anesthetic technique using 2% lidocaine with 1:100,000 epinephrine for dental procedures involving mandibular molars.
- Trial name
- NCT07771452
- Testing
- Lidocaine 2% with 1:100 000 epinephrine
- Where
- Afghanistan
- Volunteers
- 60 people
- Sponsor
- Herat University
Retrognathic Mandible
3D Characteristics, Functional Appliances and Sleep Related Breathing Disorders
Facial scans of the patients eligible for the functional appliance treatment (Twin Block appliance) will be taken prior to and after the end of treatment.
- Trial name
- FA PSQ HR (NCT06726005)
- Testing
- functional appliance twin block
- Where
- Croatia
- Volunteers
- 20 people
- Sponsor
- University of Rijeka
Congenital Heart Disease
Relationship Between Parameters of VOT Using NIRS and Clinical Outcomes in Pediatric Cardiac Surgery
The purpose of this study is to evaluate the ability of vascular occlusion test (VOT) during cardiac surgery to predict postoperative outcomes in pediatric patients.
- Trial name
- NCT02287753
- Testing
- vascular occlusion test using Pediatric SomaSensor for INVOS 5100C
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain
Indications of Erector Spinae Plane Block in Pediatric Patients
Patients who were operated by Department of Pediatric Surgery between the 1 September 2017 and 28 February 2019 and who received erector spinae plane blocks as a part of postoperative analgesia management will be scanned.
- Trial name
- NCT03906019
- Testing
- ESP Block, FLACC score, NRS score
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people
- Sponsor
- Kocaeli University
Nasal Congestion, Respiratory Tract Infection
Home Usability of a Nasal Lavage System in Children
This study evaluates labeling comprehension, ease of use and effectiveness of a new device for nasal and sinus irrigation and/or aspiration. The device is currently cleared for professional use and home use with a prescription.
- Conditions
- Nasal Congestion, Respiratory Tract Infection, Sinusitis, Allergic Rhinitis
- Trial name
- NCT01129765
- Testing
- Use of an automatic nasal irrigator/aspirator
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Aardvark Medical Company
CLASS II DIVISION 1 MALOCCLUSION
Comparative Effect of Clear Aligner Mandibular Advancement and Twin Block Appliances in Class II Malocclusion
The goal of this retrospective observational study is to compare the effects of Clear Aligner Mandibular Advancement (MA) and Twin Block (TB) appliances in treating Class II malocclusion, a condition where the lower jaw is…
- Trial name
- NCT06609733
- Testing
- Twin block, Clear aligner with mandibular function
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sichuan University
Pain
Lateral Versus Posterior Quadratus Lumborum Block in The Pediatric Patients Undergoing Orchiopexy
There is a complex innervation of the testis and spermatic canal, and many different regional analgesia methods can be used for pain occurring during and after undescended testicular surgery.
- Trial name
- NCT05056038
- Testing
- Lateral Quadratus Lumborum block, Posterior Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Istanbul University - Cerrahpasa
Aortic Stenosis, Aortic Valve Stenosis
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics)…
- Trial name
- NCT04827238
- Testing
- Standardized Invasive Hemodynamics
- Where
- 9 sites in United States, Canada
- Volunteers
- 49 people
- Sponsor
- University of British Columbia
Aortic Valve Stenosis, Transcatheter Aortic Valve Replacement
The JUMPSTART Program: Encouraging Early Mobilization and Optimizing Recovery of TAVR Patients' Post-hospital Discharge
A virtual, self-directed, and tailored early mobilization program called JUMPSTART, that aims to bridge cardiac rehabilitation intake for post-TAVR patients has been developed at the Hamilton General Hospital.
- Trial name
- NCT06040398
- Testing
- JUMPSTART exercise program
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Hamilton Health Sciences Corporation
Neurophysiological Monitoring Under TIVA
The Impact of ESP on Neurophysiological Monitoring in Scoliotic Patients
Scoliosis surgery requires intraoperative neuromonitoring. Electrophysiological monitors used include somatosensory evoked potentials (SEPS) and motor-evoked potentials (MEPS).
- Trial name
- NCT05632016
- Testing
- erector spinae block (ESP)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital
Ultrasound Localization Microscopy in Patient With Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)
This clinical study aims to non-invasively visualize perfusion and microvascularization, as well as individual glomeruli, using Ultrasound Localization Microscopy (ULM) and CEUS in patients with congenital anomalies of the kidney…
- Conditions
- Congenital Anomalies of Kidney and Urinary Tract, Lower Urinary Tract Obstruction, Congenital, Ureteropelvic Junction Obstruction, Hydronephrosis Congenital
- Trial name
- Search_CAKUT (NCT06921733)
- Testing
- Contrast enhanced ultrasound imaging (CEUS) and post processing with ULM
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Aortic Stenosis, Severe
China S3 PMS: SAPIEN 3 China Post Market Registry Study
The objective of this study is to evaluate the long term safety and effectiveness of the SAPIEN 3 Transcatheter Heart Valve system in real world setting.
- Trial name
- NCT05168826
- Testing
- SAPIEN 3 Transcatheter Heart Valve
- Where
- 14 sites in China
- Volunteers
- 250 people
- Sponsor
- Edwards Lifesciences
Coronary Arteriosclerosis, Coronary Heart Disease
Analysis of Human Coronary Aspirate
During elective percutaneous coronary intervention (PCI), both proximal and distal protection devices are used. The distal occlusion protection device temporarily occludes the vessel distal to the lesion during the intervention…
- Conditions
- Coronary Arteriosclerosis, Coronary Heart Disease, No Reflow Phenomenon
- Trial name
- AHCA (NCT01430884)
- Testing
- Aspirated Coronary Blood
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Universität Duisburg-Essen
Foreign Body Airway Obstruction
Prospective Evaluation of Foreign Body Airway Obstruction Interventions Among Infants
Foreign body airway obstruction (FBAO, choking) is a life-threatening emergency requiring time-sensitive treatment to prevent severe injury or deaths.
- Trial name
- NCT07348848
- Testing
- Chest compressions/thrusts, Back blows, Abdominal Thrusts
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- University of Calgary
Chronic Migraine Headache, Radiofrequency Ablation
The Effect of Interventional Procedures on Serum CGRP and PACAP-38 Levels in Chronic Migraine
The study included 100 patients diagnosed with chronic migraine (CM) who received a diagnosis from the headache clinics of the Neurology Department of Adnan Menderes University Hospitals between May 2025 and May 2026.
- Conditions
- Chronic Migraine Headache, Radiofrequency Ablation, Greater Occipital Nerve Block, Calcitonin Gene-related Peptide
- Trial name
- NCT07395908
- Testing
- Greater occipital nerve Pulse radiofrequency, Greater occipital nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Hand Burn
Impact of Resistance Training With and Without Venous Occlusion on Strength and Function Post (Hand Burn)
It will be hypothesized that There is There is no difference between resistance training with and without venous occlusion on hand strength and function post hand burn.
- Trial name
- hand burn (NCT07228780)
- Testing
- resistance exercise with venous occlusion, traditional resistance exercises
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cervical Cancer, Stage IIB, Cervical Cancer Stage IIIA
Clinical Trial of Laparoscopic Pelvic and Para-aortic Lymphadenectomy and Uterine Blood Vessel Blocking for Precision Diagnosis and Treatment in Advanced Cervical Cancer
Cervical cancer is the most common reproductive malignancy in developing country. Due to local invasion, radical hysterectomy cannot be performed in advanced cervical cancer (FIGO IIB - IVA) , so that radiation combined with…
- Conditions
- Cervical Cancer, Stage IIB, Cervical Cancer Stage IIIA, Cervical Cancer Stage IIIB, Cervical Cancer, Stage IVA
- Trial name
- NCT02950350
- Volunteers
- 50 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Hernia, Inguinal, Hydrocele
The Addition of Clonidine to 0.2% Ropivacaine for Wound Instillation After Minor Lower Abdominal Surgery in Children
The current study will compare the effects on postoperative pain relief of "freezing" (ropivacaine 0.2 %) alone and in combination with clonidine for a nerve block in children undergoing hernia repair.
- Trial name
- NCT00130091
- Testing
- clonidine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Anesthesia
Buccal Infiltration Anesthesia Versus Inferior Alveolar Nerve Block Anesthesia
This study aims to evaluate the effectiveness of single buccal local infiltration when compared to buccal local infiltration with intrapapillary infiltration and inferior alveolar nerve block anesthesia in primary mandibular…
- Trial name
- NCT05221190
- Testing
- Single buccal infiltration, Inferior alveolar nerve block
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Cairo University
Acute Postoperative Pain
Erector Spina Plane (ESP) Block in Pediatric Patients
In this study, we aimed to evaluate the erector spina plane (ESP) block method that we used in our clinic with ultrasonography in pediatric cases between 1 month and 2 years of age who underwent laparotomy.
- Trial name
- NCT04875390
- Testing
- Erector spina plane block, local infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
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