Clinical trials: Blood Pressure Reduction
Participation Level Below 55% and/or Special Needs
Effects of Hirudotherapy, Phytotherapy, and Forest Therapy in Adults With Reduced Work Capacity or Special Needs
This interventional study will evaluate the effects of three complementary and alternative health care services-forest therapy, phytotherapy, and hirudotherapy-in individuals with a participation level below 55% and/or special…
- Trial name
- CAM-HPMT (NCT07709221)
- Testing
- Phytotherapy, Forest Therapy, Hirudotherapy
- Where
- Lithuania
- Volunteers
- 100 people
- Sponsor
- Klaipėda University
Cardiovascular Diseases, Heart Diseases
Effects of Behavioral Stress Reduction Programs on Blood Pressure in African American Youth
This study will examine the effects of two behavioral stress reduction programs, mindfulness meditation (MM) and the lifeskills program (LP), and a health education control program (CTL) on blood pressure.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00241813
- Testing
- Mindfulness Meditation (MM) Program, Health Education Control Program (CTL), Lifeskills Program (LP)
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Medical University of South Carolina
Angina Pectoris, Coronary Heart Disease
Reducing the Pro-ischaemic Effects of Air Pollution Exposure Using a Simple Face Mask
Air pollution is a major cause of cardiorespiratory morbidity and mortality. The exact components of air pollution that underlie the cardiovascular effects are not yet known, but combustion-derived particulate matter is suspected…
- Conditions
- Angina Pectoris, Coronary Heart Disease, Blood Pressure, Heart Rate Variability
- Trial name
- NCT00809653
- Testing
- No Face Mask, Face Mask
- Where
- China
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Cardiovascular Risk Reduction
Young Hearts, Strong Starts
This is a cluster randomized trial of pediatric cardiovascular risk reduction guideline implementation in 32 clinical practices
- Trial name
- NCT01893593
- Testing
- Intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- RTI International
Cardiovascular Diseases
Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
The objective is to, among obese adolescents, study impact of regular physical activity or metformin therapy on nocturnal blood pressure and related cardiovascular disease risk factors.
- Trial name
- NCT00889876
- Testing
- Metformin group, Exercise
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Maria Sandberg Westerstahl
Metabolic Syndrome
Effect of Fish Oil on Markers of the Metabolic Syndrome in Overweight Adolescent Boys
The aim of the study is to investigate if dietary fish oil has a beneficial effect on blood pressure, insulin sensitivity, blood lipid profile, body composition and metabolic rate in healthy, but slightly overweight, teenage…
- Trial name
- TeenFisk (NCT00929552)
- Testing
- Dietary oils (fish, vegetable oil)
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Pneumonia, Human Immunodeficiency Virus (HIV)
CPAP Improving Mortality for Pneumonia in African Children Trial
Pneumonia mortality rates in African countries like Malawi are high and increased further in children -exposed or infected with human immunodeficiency virus (HIV) as well as those that are severely malnourished or severely…
- Conditions
- Pneumonia, Human Immunodeficiency Virus (HIV), Malnutrition, Hypoxemia
- Trial name
- IMPACT (NCT02484183)
- Testing
- bubble continuous positive airway pressure (CPAP)
- Where
- Malawi
- Volunteers
- 646 people
- Sponsor
- Johns Hopkins University
Primary Hypertension
Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension
Children and adolescents with primary hypertension (high blood pressure without an underlying secondary cause) are at increased risk of cardiovascular disease in adulthood.
- Trial name
- NCT07236125
- Testing
- No active intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yelda Kasımoğlu
Blood Pressure
Healthy School mEAls With Less Salt：an Action to Reduce Salt Intake in School Meals for Children in Rural China
This study aims to assess the impact of the HEALS-Child action project on children's health in rural China. The goal of the project is to evaluate the effectiveness, feasibility, safety and cost-effectiveness of two salt…
- Trial name
- HEALS-child (NCT06097884)
- Testing
- Main study intervention-Salt substitute, Main study control-Usual salt, Ancillary study intervention-Meal trays
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Hypertension
Dose Response of Valsartan on Sitting Systolic Blood Pressure in Children 6 Months - 5 Years of Age With High Blood Pressure
The purpose of this study is to evaluate the safety and efficacy of three doses of valsartan (0.25, 1.0, and 4.0 mg/kg) on mean sitting systolic blood pressure (MSSBP) and mean sitting diastolic blood pressure (MSDBP) in 6 months…
- Trial name
- NCT00435162
- Testing
- Valsartan 0.25 mg/kg, Valsartan 1.0 mg/kg, Valsartan 4.0 mg/kg
- Where
- 11 sites in United States, Belgium and 9 more
- Volunteers
- 74 people
- Sponsor
- Novartis Pharmaceuticals
Overweight, Childhood, Obesity Prevention
High Five! - School-based Prevention of Overweight and Obesity Among 6 to 9 Year Olds
The goal of this interventional study is to assess the effectiveness of the school-based "High Five!" program in reducing overweight, obesity and high blood pressure in children aged 7-9 years old.
- Conditions
- Overweight, Childhood, Obesity Prevention, Blood Pressure
- Trial name
- DINO-PL (NCT07357857)
- Testing
- High Five
- Where
- Poland
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- Institute of Mother and Child, Warsaw, Poland
Hypertension
Examining Different Modes of Exercise for Acute Reduction in Blood Pressure
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise…
- Trial name
- NCT06628635
- Testing
- Exercise, Resting
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Central Blood Pressure, Obesity
Blood Pressure and Central Vascular Stiffness in Obese Children. Relationship to Metabolic Disturbances and Subclinical Cardiovascular Damage. Effect of Weight Reduction
The global epidemic of obesity in childhood continues to evolve and threaten future health and life expectancy primarily due to the increased incidence of cardiovascular disease.
- Conditions
- Central Blood Pressure, Obesity, Subclinical Organ Damage, Children
- Trial name
- AORTA (NCT01310088)
- Testing
- Lifestyle intervention
- Where
- 2 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Cardiovascular Diseases, Hypertension
Effectiveness of an Anger and Stress Management Program on Reducing Blood Pressure Levels in Youth
High blood pressure can often be caused by stress or anxiety. This study will evaluate a school-based stress and anger management program that aims to lower blood pressure and anger levels among high school students.
- Trial name
- NCT00508612
- Testing
- Williams LifeSkills Stress and Anger Management Workshop, High school classes
- Where
- 3 sites in United States
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hypertension
Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)
Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside…
- Trial name
- NCT00621816
- Testing
- nitroprusside
- Where
- 8 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Blood Pressure
Preventing the Rise in Blood Pressure With Age Using Reduced-sodium Salt
The study is a small-scale, short-term unblinded feasibility study to explore the acceptability and feasibility of implementing a reduced-sodium iodised salt intervention in Nigeria.
- Trial name
- RAISED (NCT05912426)
- Testing
- Reduced-sodium potassium-enriched salt
- Where
- 2 sites in Nigeria
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- The George Institute
Hypertension Secondary to Kidney Transplant
Reduction of Night-time Blood Pressure in Pediatric Renal Transplant Recipients
The proposed study investigated the effect of chronotherapeutic alteration of anti-hypertensive medication on nocturnal hypertension and end-organ injury in pediatric renal transplant recipients who are non-dippers.
- Trial name
- NCT01007994
- Testing
- New Medication: Enalapril, Isradipine, Propranolol
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Northwell Health
Asthma, Obesity
Reducing Socioeconomic Disparities in Health at Pediatric Visits
This research project is aimed to assess the effectiveness and impact of a pediatric-based intervention aimed at reducing low-income families' unmet material needs (food, housing, employment, childcare, household heat, education…
- Conditions
- Asthma, Obesity, Health Care Utilization, Health Care Disparities
- Trial name
- WECARE01 (NCT02451059)
- Testing
- WE CARE survey, WE CARE Community Resource Handout, Patient Navigator
- Where
- 6 sites in United States
- Volunteers
- 1,205 people
- Sponsor
- Boston Medical Center
Cardiovascular Disease
High Cardiovascular Risk Management and Salt Reduction in Rural Villages in China
Cardiovascular disease is the leading cause of death in China. At the village level, strategies for the control of cardiovascular disease are mostly absent.
- Trial name
- NCT01259700
- Testing
- High-risk patient standardized management package, Community based salt reduction program
- Where
- 5 sites in China
- Volunteers
- 120 people
- Sponsor
- The George Institute for Global Health, China
Blood Pressure, Heart Rate Variability
The Cardiovascular Benefits of Reducing Personal Exposure to Air Pollution
Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia.
- Trial name
- NCT00809432
- Testing
- Face mask (Dust Respirator), No Face mask
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh