Clinical trials: Body Fat
Non-Alcoholic Fatty Liver Disease
Ultrasound Quantification of Liver Fat
The investigators plan a prospective study designed to evaluate the accuracy of a new ultrasound method for quantification of liver fat content.
- Trial name
- NCT04523584
- Testing
- Magnetic Resonance Imaging (MRI), Ultrasound Imaging
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cleft Palate
Repair of Oronasal Fistula Using Interpositional Buccal Pad of Fat as a Free Graft in a Cleft Palate Patient
36 cleft palate patients had residual oronasal fistula included in this study divided randomly to two groups group I (control group): the fistula was repaired using two layers (oral and nasal layers) group II (study group): The…
- Trial name
- NCT06807450
- Testing
- closure of oro-nasal fistula in cleft palate patients
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tanta University
Physical Fitness, Adiposity
Effects of a 10-Week Zumba Program on Adiposity and Flexibility in 8-Year-Old Children
The purpose of this study is to investigate the effects of a 10-week Zumba dance-based exercise program on body fat (adiposity) and flexibility in healthy 8-year-old children.
- Trial name
- NCT07512349
- Testing
- Zumba Dance-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ege University
Obesity, Hypercholesterolemia
Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents
The purpose of this research is to investigate the effects of a PB no- added-fat and the AHA and MED in obese (BMI >95%) children ages 9-18 with hypercholesterolemia (>169 mg/dl) and a parent or guardian.
- Conditions
- Obesity, Hypercholesterolemia, Cardiovascular Disease
- Trial name
- NCT02857543
- Testing
- Plant-Based Diet, American Heart Association Diet, Mediterranean Diet
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- The Cleveland Clinic
Lateral Gluteal Depression
Analyze Previously Collected Biopsy Samples From Participants Who Completed the "SPLASH: Split-Body Randomized Clinical Trial of Poly-L-Lactic Acid for Adipogenesis and Volumization of the Hip Dell" Study
Primary Objective: use immunofluorescence (IF) on previously obtained biopsies to analyze and quantify changes in adipose tissue of subjects injected with poly-L-lactic acid (PLLA) or saline.
- Trial name
- NCT06656923
- Testing
- Biopsies
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Autologous Fat Graft Harvesting, SVF-gel Preparation and Filling, CO2 Fractional Laser Treatment by Using Acupulse Device
Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment
Background Adipose extracellular matrix/stromal vascular fraction gel（SVF-gel）, which contains adipose-derived stem cells, endothelial cells, smooth muscle cells, pericytes, and other cell components.
- Trial name
- NCT06116162
- Testing
- SVF-gel Filling and CO2 fractional laser
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- Xijing Hospital
Hyaluronic Acid, Fat Graft
Clinical Evaluation of Interdental Papilla Reconstruction Using Injectable Autogenous Fat Versus Hyaluronic Acid Filler.
The goal of this randomized controlled trial is to evaluate the amount of interdental papilla fill following the injection of the fat graft compared to hyaluronic acid filler in patients with interdental papilla deficiency.
- Trial name
- NCT05579522
- Testing
- Fat graft injection, Hyaluronic acid injection
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hepatic Steatosis, Bariatric Surgery Candidate
Hepatic Mitochondrial Function in Youth
Assess the impact of bariatric surgery on hepatic energy metabolism and glucose and insulin dynamics in obese youth
- Conditions
- Hepatic Steatosis, Bariatric Surgery Candidate, Adolescent Obesity, Obesity
- Trial name
- MANGO (NCT03587727)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Breast Feeding
Newborn Feeding and Infant Phenotype
Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism.
- Trial name
- NCT02033005
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity
Metabolic Differences of Overweight Children and Children of Overweight Parents
This study focuses on the way weight is gained. Individuals who gain weight primarily in their midsection (visceral weight) are at an increased risk for developing diabetes and high blood pressure.
- Trial name
- NCT00001522
- Where
- United States
- Volunteers
- 246 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diabetes Mellitus, Type 1
What is the Dose Response of Varying Meal Content of Fat on Postprandial Glycaemia in Children With T1DM?
Background: Based on international evidence, current management of people with T1DM on intensive insulin therapy (IIT) use algorithms based on the meal carbohydrate content (MCC) to calculate the prandial insulin dose.
- Trial name
- REQINSOIL (NCT02371694)
- Testing
- Test drink
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Cork University Hospital
Dumping Syndrome, Gastric Surgery
Fat Supplementation on Dumping Syndrome Related Symptoms After Gastric Surgery
The purpose of the study is the investigation of the effect of fat supplement on gastric emptying rate and the appearance of symptoms of Dumping Syndrome in patients who have undergone gastrointestinal- duodenal surgery.
- Trial name
- NCT05759689
- Testing
- Dietary Supplement: Resource Energy, Dietary Supplement: Calogen
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Larissa University Hospital
Non-alcoholic Fatty Liver Disease
Fructose and Liver Diseases in Youth: Help Them FLY
Obesity has been increasing all over the world. This has lead to a significant increase of a liver disease in children called non-alcoholic fatty liver disease (NAFLD).
- Trial name
- FLY (NCT05528471)
- Testing
- Dietary intervention
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Alberta
Diabetes Mellitus, Type I
Effect of the Fat Content of the Bedtime Snack on Overnight Hypoglycemia
Low blood sugar at night (called nocturnal hypoglycemia), can often happen without symptoms and can last for a long time. Doctors often suggest that patients take a bedtime snack to try to prevent low blood sugar at night from…
- Trial name
- NCT00493935
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Jaeb Center for Health Research
Pancreatic Cancer
Changes in Muscle Tissue in Patients With Pancreatic Cancer
RATIONALE: Measuring changes in muscle tissue in patients with cancer may help doctors predict how well patients will respond to treatment, and may help the study of cancer in the future.
- Trial name
- NCT00369460
- Testing
- physiologic testing
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Case Comprehensive Cancer Center
Cystic Fibrosis
Development Of An Innovative Panel of Methods To Measure Intestinal Macronutrient Digestion, Absorption, and Function
Malnutrition is a significant problem in children and adults with Cystic fibrosis (CF). An impaired intestinal digestion and absorption capacity is one of the main factors responsible for the malnutrition in CF.
- Trial name
- NCT01494909
- Testing
- Ensure plus
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Adolescent Behavior
Effects of Self-efficacy, Planning, and Self-efficacy+Planning Interventions on Body Fat Among Adolescents
This longitudinal experimental study tested the effects of three brief interventions: (1) prompting the formation of plans (or implementation intentions), (2) prompting self-efficacy beliefs, and (3) prompting planning +…
- Trial name
- NCT02689973
- Testing
- Self-Efficacy, Planning, Education
- Where
- Poland
- Volunteers
- 1,217 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Chylothorax
Dietary Treatment of Infants With Chylothorax
Chylothorax occurs in ~3 to 5 % of infants undergoing cardiac surgery. Standard treatment requires discontinuation of breast milk feeding, due to the abundance of long chain triglycerides, and transition to a medium chain…
- Trial name
- NCT02143557
- Testing
- Fat-Modified Breast Milk, MCT formula
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- The Hospital for Sick Children
Severe Acute Malnutrition, Cognitive Impairment
Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition
The goal of this clinical trial is to test the use of milk fat globule membrane (MFGM) in ready-to-use therapeutic food (RUTF) in children with severe acute malnutrition in Sierra Leone.
- Conditions
- Severe Acute Malnutrition, Cognitive Impairment, Kwashiorkor, Severe Wasting
- Trial name
- MEND-SAM (NCT06869850)
- Testing
- MFGM-RUTF (milk fat globule membrane ready-to-use therapeutic food), S-RUTF (standard ready-to-use therapeutic food), Amoxicillin
- Where
- 10 sites in Sierra Leone
- Volunteers
- 1,600 people
- Sponsor
- Washington University School of Medicine
Healthy Term Infant
Healthy Term Infants Fed Milk-Based Formulas
The objective is to assess the comparative fat and calcium absorption, and gastrointestinal (GI) tolerance in healthy normal term infants fed powdered milk-based formulas containing different fat blends.
- Trial name
- NCT01617889
- Testing
- Experimental powdered milk-based infant formula with an alternate fat blend, A powdered milk-based infant formula, standard fat blend
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition