Clinical trials: Body Weight Control
Pediatric Obesity
Juntos Santiago: Gamification Strategy to Reduce Childhood Obesity in Schools in Santiago de Chile
School-based interventions have shown mixed results. Most studies have lacked enough statistical power and have been carried out in North America and Europe.
- Trial name
- NCT03459742
- Testing
- Gamification strategy
- Where
- 2 sites in Chile
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Municipality of Santiago
Gastroesophageal Reflux Disease, Excessive Weight Loss
Sleeve Gastrectomy With Reestablishment of the Acute Angle of His (SG-REACH) in Obese Patients
Gastroesophageal reflux disease (GERD) is one of the most common chronic conditions that can affect one's quality of life. Laparoscopic sleeve gastrectomy (LSG) has become a popular technique and currently is the most frequently…
- Conditions
- Gastroesophageal Reflux Disease, Excessive Weight Loss, Total Weight Loss, Sleeve Gastrectomy
- Trial name
- SG-REACH (NCT05452980)
- Testing
- reestablishment of the acute angle of His, sleeve gastrectomy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Zhen Jun Wang
Type 1 Diabetes, Eating Behavior
Type 1 Diabetes Adolescents for Healthier Lifestyles Study
Before the 1990s, obesity was rare among young people with type 1 diabetes (T1D), but now it is more common. Recent studies show that over 50% of young people with T1D will have overweight or obesity within five years of being…
- Conditions
- Type 1 Diabetes, Eating Behavior, Adolescent Obesity
- Trial name
- T1DAL (NCT06878872)
- Testing
- T1DAL Program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Miriam Hospital
Dietary Behavior
Lunch is in the Bag: Helping Parents Increase Fruit, Vegetables, and Whole Grains in Preschool Sack Lunches
Lunch is in the Bag is an intervention designed to increase fruits, vegetables, and whole grains in sack lunches prepared for preschool children.
- Trial name
- LIITB (NCT01292434)
- Testing
- Lunch is in the Bag behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 1,266 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Obesity
Probiotics Effect on Glucose and Lipid Metabolism and Gut Microbiota in Patients With Obesity
The purpose of this study is to determine whether the probiotics will be effective in the treatment of obesity
- Trial name
- NCT02733484
- Testing
- Probiotics
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Obesity, Body Weight Changes
Modifying the Home Television Watching Environment
The purpose of this study is to determine if limiting television (TV) and computer time will result in a stabilization or smaller increase in body mass index (BMI), lower energy intake, and increased physical activity in 4-7 year…
- Trial name
- NCT00065052
- Testing
- Behavior modification
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Morbid, Bariatric Surgery
Adjunct Phentermine + Topiramate After Bariatric Surgery in 12-24 Year Olds
The goal of this pilot study is to establish the feasibility and initial efficacy of the combination of phentermine and topiramate for adolescents and young adults who require additional risk reduction after bariatric surgery.
- Conditions
- Obesity, Morbid, Bariatric Surgery, Adolescent, Young Adult
- Trial name
- NCT04095104
- Testing
- Phentermine, Immediate Release Topiramate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Child Obesity
Attrition in Pediatric Obesity Management
Our feasibility study will assess the feasibility and acceptability of Family Navigation (FN) to address attrition (dropout) in pediatric obesity management.
- Trial name
- NCT05403658
- Testing
- Family Navigation, Usual Care
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- University of Alberta
Mental Health, Child Wellbeing
Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Generation Victoria (GenV) is a longitudinal, population-based study of Victorian children and their parents that will bring together data on a wide range of conditions ,exposures and outcomes.
- Conditions
- Mental Health, Child Wellbeing, Infant Health, Child Health
- Trial name
- GenV (NCT05394363)
- Where
- Australia
- Volunteers
- 150,000 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Obesity & Overweight, Weight Loss
Sustaining Health After an Intensive Weight-loss Pro-gramme
Since 2021 Copenhagen University Hospital - Hvidovre, Denmark, has offered a 2-year, highly specialised, intensive clinical weight loss programme to patients living with severe and complex obesity, who due to somatic and/or…
- Conditions
- Obesity & Overweight, Weight Loss, Weight Management in Adult Patients With Obesity or Overweight
- Trial name
- SHAPe (NCT07900178)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Chronic Kidney Disease, Proteinuria
A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria
Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine.
- Trial name
- FIONA (NCT05196035)
- Testing
- Finerenone (Kerendia, BAY94-8862)
- Where
- 132 sites in United States, Argentina and 30 more
- Volunteers
- 219 people
- Sponsor
- Bayer
Weight Gain
Growth and Safety Clinical Trial on a New Infant Formula
The aim of this study is to assess age-appropriate growth of healthy infants fed a new infant formula. In this randomized, controlled trial, healthy, term, formula-fed infants will be randomized to one of two infant formulas: a…
- Trial name
- NCT05508750
- Testing
- New Infant Formula, Commercial Infant Formula
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Jovie USA, LLC
Driving Pressure, Positive End-expiratory Pressure
Driving Pressure-guided Positive End-expiratory Pressure to Prevent Postoperative Atelectasis in Obese Children: a Prospective, Randomized Controlled Clinical Trial
At present, the use of lung protective ventilation strategies in children is mainly based on adult and intensive care unit data.
- Conditions
- Driving Pressure, Positive End-expiratory Pressure, Postoperative Atelectasis, Obese
- Trial name
- NCT06471491
- Testing
- Driving pressure-guided positive end-expiratory pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Henan Provincial People's Hospital
Obesity
The Effect of the Oligofructose Supplementation on Body Weight in Overweight and Obese Children
This study is designed to assess the effect of oligofructose administration for 12 weeks on Body Mass Index (BMI) of overweight and obese children.
- Trial name
- NCT01673152
- Testing
- Oligofructose, Maltodextrin
- Where
- Poland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Obesity, Childhood
Addressing the Social Needs of Children With Obesity
This study aims to improve the treatment of a common, chronic health concern for children: obesity. It has the potential to improve the care we provide by testing an intervention that addresses social needs and the important…
- Trial name
- NCT04711707
- Testing
- Community navigator, Self-Navigation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Hamilton Health Sciences Corporation
Childhood Obesity
The Optimising Family Engagement in HENRY (OFTEN) Study
This study will test whether parent engagement (recruitment, attendance) in a Childhood obesity prevention programme (HENRY) can be improved in local authorities randomised to receive an Optimisation intervention (in addition to…
- Trial name
- OFTEN (NCT02675699)
- Testing
- Optimisation + HENRY, HENRY as standard
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Breast Cancer, Obesity
Rural Women Connecting for Better Health
Women who are obese at breast cancer diagnosis have a 1.5 to 2.5 increased risk of recurrence and death compared to their normal weight counterparts.
- Trial name
- NCT01441011
- Testing
- Group phone counseling, Newsletter
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Kansas Medical Center
Obesity
Promoting Child Inhibitory Control Skills Around Food
Today's environment provides many hedonic stimuli that promote consumption of unhealthy energy-dense snack foods. It is widely recognized that a systems approach is required to deal with this complex problem.
- Trial name
- CHIC Play (NCT02077387)
- Testing
- CHild Inhibitory Control (CHIC) Play, Attention control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
The main purpose of this study, performed under Master Protocol J4M-MC-PWMP (NCT06672549), is to evaluate the efficacy, safety, and pharmacokinetics of tirzepatide as an addition to healthy lifestyle in participants 6 to less…
- Trial name
- NCT07817875
- Testing
- Tirzepatide
- Where
- 82 sites in United States, Belgium and 8 more
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company