Clinical trials: Bone Healing
Proximal Humerus Fracture
Hanover Humerus Registry
This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or…
- Trial name
- HHR (NCT03060876)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Microfractures, Meniscus Tear
The Effectiveness of the Microfracture Technique in the Meniscal Healing
Meniscus injuries are a very common cause of knee pain. The meniscus is a semilunar fibrocartilage structure found on the medial and lateral sides of the knee.
- Trial name
- NCT05799196
- Testing
- Microfracture
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Hasanuddin University
Fractures, Bone, Upper Extremity Injury
Ultrasonography in Fracture Management
The bone fracture is usually diagnosed using an X-ray examination (the method of choice). However, in the case of the youngest patients (children and adolescents), it carries a potential risk of X-ray radiation exposure.
- Conditions
- Fractures, Bone, Upper Extremity Injury, Healing Fracture of Bone, Vascularization
- Trial name
- UFrac (NCT04501510)
- Testing
- Ultrasonographic examination validation and testing
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- University of Warmia and Mazury
Temporomandibular Joint Disorders
Clinical and Magnetic Resonance Imaging Evaluation of Micro Fragmented Adipose Tissue Injection Combined With Bone Marrow Stem Cells on Healing of Temporomandibular Joint Internal Disc Derangement Without Reduction
Arthrocentesis of TMJ then injection of micro fragmented adipose tissue mixed with bone marrow aspirate on healing of TMJ internal disc derangement without reduction.
- Trial name
- NCT05815771
- Testing
- Micro fragmented adipose tissue mixed with bone marrow stem cells, Bone Marrow stem cells aspirate
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Mohamed Talaat Abbas Hassan
Periapical Periodontitis, Periradicular Lesion
Accuracy and Healing Outcomes of Endodontic Surgery Using a Static Surgical Guide.
The goal of this clinical trial is to evaluate the surgical accuracy and healing outcomes of endodontic surgery performed with the assistance of a 3D-printed static surgical guide in patients requiring apicoectomy.
- Conditions
- Periapical Periodontitis, Periradicular Lesion, Endodontic Treatment Failure, Postoperative Wound Healing
- Trial name
- NCT07734987
- Testing
- 3D-Printed Static Surgical Guide and Trephine Bur, Ultrasonic Retrograde Preparation and Bioceramic Retrograde Obturation
- Where
- Vietnam
- Volunteers
- 11 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Simple Bone Cyst
Quantitative Ultrasound for the Evaluation of Simple Bone Cyst Healing
Simple bone cysts (SBCs), also known as unicameral bone cysts (UBCs), are benign bone lesions. Literature to date describes little agreement between clinicians on specific prognostic criteria for the prediction of cyst healing…
- Trial name
- NCT02616757
- Testing
- Sunlight Omnisense Quantitative Ultrasound
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Infections
Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material
Infections associated with osteosynthesis material are among the most feared and challenging complications of trauma surgery and can lead to total function loss or limb amputation when complete recovery is to be expected without…
- Trial name
- DURATIOM (NCT05294796)
- Testing
- Short course of antibiotherapy, Long course of antibiotherapy
- Where
- 29 sites in Spain
- Volunteers
- 364 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Fractures, Bone
Biomechanical Analysis of Distal Radius (Greenstick) Fracture Healing
The study will be conducted to investigate the effects of electrical charges (flexoelectric effect) \& mechanical brachioradialis muscle bending force on the displacement and strain of fracture gap on children with Distal radius…
- Trial name
- NCT06510595
- Testing
- Active Treatment Arm, Control Treatment Arm
- Volunteers
- 2 people
- Sponsor
- Cairo University
Vitamin D, Long Bone Fracture
Longitudinal Study of Patients Following Long Bone Fracture
Studies in chickens show that blood levels of a particular form of vitamin D (called 24,25-dihydroxvitamin D) increase after bone fracture.
- Trial name
- NCT01170572
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Barts & The London NHS Trust
Radius Fractures
Association Between Hand-Eye Coordination and Handgrip Strength in Children Post-Healing of DRGF
The study investigates whether hand-eye coordination is related to handgrip strength in children (aged 5-12 years) after they have healed from distal radius greenstick fractures.
- Trial name
- NCT07037355
- Testing
- Handgrip Strength and Hand-Eye Coordination Assessment
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Superior University
Forearm Fracture, Clavicle Fracture
Bone Ultrasound to Access Fracture Healing
The purpose of this study is to evaluate sequential fracture healing with radius/ulna fractures or clavicle fractures and compare ultrasound to radiographs.
- Trial name
- NCT02769117
- Testing
- Ultrasound on fractured bone, Ultrasound on contralateral intact bone
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Bone Tumors
Vascular CT Assessment of Structural Autograft and Allograft Healing
The purpose of this study is to determine the ability of a cone beam CT to measure bone healing.
- Trial name
- NCT00594776
- Testing
- Cone Beam CT Scan
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Rochester
Fractures
The Effect of NSAID Use in the Acute Phase of Skeletally Immature Bone Healing: A Prospective Study
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in children with fractures or those who have surgery to correct bony deformity requiring the bone to be cut…
- Trial name
- NCT02076321
- Testing
- Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Missouri-Columbia
Ewing Sarcoma, Bone Neoplasms
Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma
This is a single-center, single-arm, prospective observational study to evaluate the long-term local control rate, safety, and efficacy of preoperative neoadjuvant radiotherapy (36-45 Gy) followed by sequential radical surgery…
- Trial name
- NCT07620431
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University People's Hospital
Osteoarthritis, Knee
Prospective Evaluation of PRP and BMC Treatment to Accelerate Healing After ACL Reconstruction
This is a prospective, randomized, placebo-controlled trial to evaluate potential beneficial effects of leukocyte-poor platelet rich plasma and bone marrow concentrate on the healing and health of critical joint tissues in the…
- Trial name
- NCT04205656
- Testing
- Leukocyte-Poor Platelet Rich Plasma (LP-PRP), Bone Marrow Concentrate (BMC)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Steadman Philippon Research Institute
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Rotator Cuff Tear
Evaluation of Tendon-to-Bone Healing Potential in Arthroscopic Rotator Cuff Repair Through Biological Stimulation
Evaluation of clinical and radiological outcomes in patients undergoing Arthroscopic Rotator Cuff Repair with standard treatment compared to patients receiving biological stimulation with micro-perforations or with the…
- Trial name
- NCT03060928
- Testing
- Arthroscopic Rotator Cuff Repair, Micro-perforations, Artelon®
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- ASST Gaetano Pini-CTO