Clinical trials: Bone Healing
Fractures, Bone
Biomechanical Analysis of Distal Radius (Greenstick) Fracture Healing
The study will be conducted to investigate the effects of electrical charges (flexoelectric effect) \& mechanical brachioradialis muscle bending force on the displacement and strain of fracture gap on children with Distal radius…
- Trial name
- NCT06510595
- Testing
- Active Treatment Arm, Control Treatment Arm
- Volunteers
- 2 people
- Sponsor
- Cairo University
Fracture Healing, Distal Radius Fracture
Local Remodelling of Bone Fracture Healing
The aim of our study is to improve a mathematical model (FAE) of human bone healing using the example of the distal spoke fracture.
- Trial name
- NCT04783337
- Testing
- HR-pQCT (high resolution computertomograph), Blood withdrawal
- Volunteers
- 106 people
- Sponsor
- Medical University Innsbruck
Microfractures, Meniscus Tear
The Effectiveness of the Microfracture Technique in the Meniscal Healing
Meniscus injuries are a very common cause of knee pain. The meniscus is a semilunar fibrocartilage structure found on the medial and lateral sides of the knee.
- Trial name
- NCT05799196
- Testing
- Microfracture
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Hasanuddin University
Proximal Humerus Fracture
Hanover Humerus Registry
This register study collects data of patients with proximal humerus and humerus shaft fractures to monitor the healing process by assessing shoulder function and quality of life according to the treatment method (operative or…
- Trial name
- HHR (NCT03060876)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Tooth Loss, Tooth Injury
Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young Patients
This study aims to evaluate the clinical, radiographic, functional, and patient-reported outcomes of premolar autotransplantation used to replace anterior maxillary teeth in young patients.
- Trial name
- YATA (NCT07314580)
- Testing
- Premolar Autotransplantation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Avulsion
Healing Assessment of External Inflammatory Root Resorption After Revascularization Technique of Avulsed Permanent Central Incisor (Case Study)
Evaluate the healing of external root resorption of replanted avulsed permanent maxillary central incisor after revascularization.
- Trial name
- (EIRR) (NCT06785961)
- Testing
- Regeneration of traumatic tooth
- Where
- Egypt
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Badr University
Impacted Third Molar Tooth
Assessment of Bone Density in Impacted Mandibular Third Molar
Preoperative radiograph will be taken to assess the type of impaction either mesioangular, horizontal, distoangular and check mouth opening. Two groups involve in my study.
- Trial name
- NCT05944939
- Testing
- Surgical extraction of impacted third molar
- Where
- 2 sites in Pakistan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Adolescence Idiopathic Scoliosis
A Randomized Intra-Patient Controlled Trial of MagnetOs™ Putty vs Autograft in Instrumented Posterolateral Spinal Fusion in Idiopathic Scoliosis Patients
SUMMARY Rationale: Delayed union is a problem in adolescent idiopathic scoliosis (AIS) surgery, especially at the distal end of the construct.
- Trial name
- MAIS (NCT07512336)
- Testing
- MagnetOs putty 2.5cc, autograft
- Volunteers
- 140 people
- Sponsor
- UMC Utrecht
Ewing Sarcoma, Bone Neoplasms
Neoadjuvant Radiotherapy and Surgery for High-Risk Localized Ewing Sarcoma
This is a single-center, single-arm, prospective observational study to evaluate the long-term local control rate, safety, and efficacy of preoperative neoadjuvant radiotherapy (36-45 Gy) followed by sequential radical surgery…
- Trial name
- NCT07620431
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University People's Hospital
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Bone Regeneration, Periodontal Bone Loss
Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects
Due to their osteoconductive, osteoinductive, and osteogenic qualities, autologous bone grafts are the gold standard for augmenting bone, (1).
- Conditions
- Bone Regeneration, Periodontal Bone Loss, Healing Fracture of Bone
- Trial name
- Nitro- Bone (NCT06925763)
- Testing
- Nitroglycerin
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Minia University
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Infections
Efficacy and Safety of Antimicrobial Durations Treatment of Infections Associated With Osteosynthesis Material
Infections associated with osteosynthesis material are among the most feared and challenging complications of trauma surgery and can lead to total function loss or limb amputation when complete recovery is to be expected without…
- Trial name
- DURATIOM (NCT05294796)
- Testing
- Short course of antibiotherapy, Long course of antibiotherapy
- Where
- 29 sites in Spain
- Volunteers
- 364 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Bone Sarcoma, Osteosarcoma
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous…
- Conditions
- Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma
- Trial name
- NCT03442465
- Testing
- Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score, Timed Get Up and Go Test
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Temporomandibular Joint Disorders
Clinical and Magnetic Resonance Imaging Evaluation of Micro Fragmented Adipose Tissue Injection Combined With Bone Marrow Stem Cells on Healing of Temporomandibular Joint Internal Disc Derangement Without Reduction
Arthrocentesis of TMJ then injection of micro fragmented adipose tissue mixed with bone marrow aspirate on healing of TMJ internal disc derangement without reduction.
- Trial name
- NCT05815771
- Testing
- Micro fragmented adipose tissue mixed with bone marrow stem cells, Bone Marrow stem cells aspirate
- Where
- 2 sites in Egypt
- Volunteers
- 24 people
- Sponsor
- Mohamed Talaat Abbas Hassan
Bone Healing
Ultrasound Monitoring of Bone Healing in Ilizarov Bone Transport
This prospective study evaluates the role of ultrasound in assessing bony union during Ilizarov bone transport. Ultrasound findings will be compared with radiographic and clinical outcomes to determine its accuracy in detecting…
- Trial name
- NCT07505433
- Testing
- Ultrasound
- Volunteers
- 56 people
- Sponsor
- Assiut University
Fracture Healing, Vitamin D3
The Vitamin K2 and D3 Intervention Trial in Children and Adolescents With the Low-energy Fractures
a prospective, three- month, randomized, double-blind, placebo-controlled, intervention trial (RDBPC), investigating the effect of vitamin K2 (menaquinone-7) and vitamin D3 on the healing process of low-energy bone fractures in…
- Conditions
- Fracture Healing, Vitamin D3, Deficiency of Vitamin K2
- Trial name
- NCT03871322
- Testing
- Vitamin D and K2 supplementation, Vitamin D supplementation
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Rotator Cuff Tear
Evaluation of Tendon-to-Bone Healing Potential in Arthroscopic Rotator Cuff Repair Through Biological Stimulation
Evaluation of clinical and radiological outcomes in patients undergoing Arthroscopic Rotator Cuff Repair with standard treatment compared to patients receiving biological stimulation with micro-perforations or with the…
- Trial name
- NCT03060928
- Testing
- Arthroscopic Rotator Cuff Repair, Micro-perforations, Artelon®
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- ASST Gaetano Pini-CTO
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital