Clinical trials: Bone Mineral Density
Low Bone Mass
Resveratrol for the Prevention of Bone Loss in Postmenopausal Women
The purpose of this study is to examine whether daily supplementation of resveratrol would improve bone health in postmenopausal women.
- Trial name
- NCT06250283
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Osteopenia, Osteoporosis
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation
This is a Phase 2, open-label, randomized, controlled clinical study of pediatric subjects treated with pamidronate with calcium and vitamin D versus calcium and vitamin D alone following hematopoietic cell transplantation (HCT).
- Trial name
- NCT02074631
- Testing
- Pamidronate, Calcium and vitamin D
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Bone Density, Pain
Bisphosphonate Therapy in MONA Spectrum Disorder
Multicentric osteolysis, nodulosis and arthropathy (MONA) spectrum disorder is a rare inherited progressive skeletal disorder caused by mutations in the matrix metalloproteinase 2 (MMP2) gene. Treatment options are limited.
- Conditions
- Bone Density, Pain, Fracture
- Trial name
- NCT02823925
- Testing
- Pamidronate or Zoledronate
- Volunteers
- 3 people
- Sponsor
- Medical University Innsbruck
Osteoporosis
GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients
The study is designed as a retrospective, single-center study for subjects previously treated with the AGN1 LOEP Kit. This will be a non-randomized and non-blinded study.
- Trial name
- NCT05966974
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- AgNovos Healthcare, LLC
Idiopathic Hypoparathyroidism, Autosomal Dominant Hypocalcaemia
Characterization of Patients With Non-surgical Hypoparathyroidism and Pseudohypoparathyroidism
Hypoparathyroidism (hypoPT) and pseudohypoparathyroidism (Ps-hypoPT) are rare diseases, characterized by low levels of parathyroid hormone [PTH] and plasma calcium or high plasma PTH and low plasma calcium, respectively.
- Conditions
- Idiopathic Hypoparathyroidism, Autosomal Dominant Hypocalcaemia, Pseudohypoparathyroidism
- Trial name
- NCT02551120
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Burn, Growth
Bone Mineral Density, Body Composition and Growth Following Severe Burn Injury
The purpose of this study is two-fold. The first is to establish that bone mineral density is diminished among children admitted to this regional burn center as compared to healthy non-burned children.
- Conditions
- Burn, Growth, Malnutrition
- Trial name
- NCT00285090
- Testing
- Calcium, Vitamin D, Calcium,Vitamin D, Calcium, VitaminD
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kathy Prelack, PhD, RD
Malocclusion, Angle Class II, Division 1
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399760
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Amenorrhea
Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea
The study aims to evaluate the outcomes of different estrogen therapy regimens in patients with amenorrhea who face prolonged periods of hypoestrogenism.
- Trial name
- NCT07015476
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Osteoporosis
A Randomized, Double-blind, Placebo-controlled, Dose Response Study of AMG 162 (Denosumab) in Japanese Postmenopausal Osteoporotic Subjects
The primary objective of this study is to assess the effect of AMG 162 (denosumab) treatment on the lumbar spine BMD at month 12 and safety profile across the dose range tested (14, 60 and 100 mg SC once every 6 months) in…
- Trial name
- NCT00306189
- Testing
- 100 mg AMG 162, 60 mg AMG 162, 14 mg AMG 162
- Volunteers
- 212 people
- Sponsor
- Amgen
Osteopenia
Study to Evaluate the Safety and Efficacy of Seasonale for Treatment of Low Bone Mineral Density
This is a randomized, multicenter, placebo-controlled study to evaluate the effects of Seasonale, an extended-regimen oral contraceptive, on bone mineral density in adolescent females who have had their menstrual period but now…
- Trial name
- NCT00117260
- Testing
- Seasonale (levonorgestrel and ethinyl estradiol)
- Sponsor
- Duramed Research
Healthy
The Effect of Dairy on Bone Mass and Body Composition in 4th-8th Grade Boys and Girls
Building stronger bones during pubertal growth could reduce lifelong fracture risk. This project is an 18 month dairy intervention study for overweight and healthy weight 4th-8th grade boys and girls.
- Trial name
- B3 (NCT00635583)
- Testing
- Increased Dairy Consumption
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Osteoporosis
Effects of Jumping on Growing Bones
In this study we will investigate the effects of a high-impact exercise program involving jumping on bone mass (the amount of bone) of the hip and backbone in the growing skeleton.
- Trial name
- NCT00000405
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon State University
Osteopenia Of Prematurity
A Preliminary Study of Bone Density in Neonates
The study is to measure how dense or solid the infant's bones are using a new ultrasound machine and how that density changes over time.
- Trial name
- NCT00631397
- Testing
- Ultrasound machine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hypercalciuria; Idiopathic, Nephrolithiasis
Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria
The investigator's objective is to compare and evaluate the impact of nutritional treatment vs. pharmacological treatment (hydrochlorothiazide) in bone mineral density in children with idiopathic hypercalciuria.
- Trial name
- HIC (NCT03951558)
- Testing
- Diet for calciuria prevention, Hydrochlorothiazide
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez
Soccer, Bone Density
Effect of the Interaction Between the Type of Artificial Turf and Boots Model of Bone Health in Children Soccer Players
The number of turf fields has experienced an important increase in public and private facilities during the last years. This artificial surface will be predominant in any soccer field in the next years.
- Conditions
- Soccer, Bone Density, Physical Fitness
- Trial name
- FUTBOMAS (NCT02399553)
- Testing
- Soccer boot intervention
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Vitamin D Deficiency, Injuries
Vitamin D Status Among Competitive Female Gymnast and Swimmers After Winter Time
As indoor athletes, competitive gymnasts and swimmers can face the problem of a potential vitamin D deficiency. In the last decades, indoor sports participants have been faced with the problem of an institutionalized lifestyle…
- Conditions
- Vitamin D Deficiency, Injuries, Cardiovascular Risk Factor, Nutritional Deficiency
- Trial name
- NCT03584256
- Where
- Slovenia
- Volunteers
- 31 people
- Sponsor
- University of Ljubljana
Disorder of Bone Density and Structure, Unspecified
Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Adolescents and young adults with anorexia nervosa (AN) are at high risk for low bone mineral density at a time when healthy adolescents are rapidly accruing bone, with implications for peak bone mass and fracture risk in later…
- Trial name
- 814 (NCT00720122)
- Testing
- Recombinant human insulin like growth factor-1 (rhIGF-1)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Massachusetts General Hospital
Bone Mineral Content, Bone Density
The KOMOtini BONE Study: Evaluation of the Osteogenic Potential of Sports
Bone mass develops throughout childhood and adolescence until a peak bone mass is achieved during early adulthood. Fracture risk later in life can be predicted at a large extent by peak bone mass.
- Conditions
- Bone Mineral Content, Bone Density, Bone Turnover Markers, Athletic Performance
- Trial name
- KOMO-BONE (NCT03201302)
- Testing
- School physical education class, Taekwondo, Martial arts
- Where
- Greece
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Ioannis G. Fatouros
Osteopenia, Postmenopausal Osteopenia
Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides in Postmenopausal Women With Osteopenia
Osteoporosis is undoubtedly one of the most common diseases affecting older individuals with debilitating consequences. Osteopenia, defined as T-score between -1 and -2.5, has also been associated with increased risk of…
- Trial name
- NCT03999775
- Testing
- Calcium, vitamin D and bioactive collagen peptides supplement, Calcium and vitamin D supplement
- Volunteers
- 51 people
- Sponsor
- Ioannis K. Triantafyllopoulos, MD,MSci,PhD