Clinical trials: Bone Mineral Density
Osteoporosis
Building Better Bones in Children
Calcium is important for healthy bone growth in children. Poor bone growth and development during childhood can lead to osteoporosis later in life.
- Trial name
- NCT00063037
- Testing
- Behavioral modification - nutrition education
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteoporosis
The Effect of Norgestimate/Ethinyl Estradiol on Bone Density in Pediatric Subjects With Anorexia Nervosa
The purpose of this study is to evaluate the effect of norgestimate/ethinyl estradiol on lumbar spine (L1-L4) and total hip bone mineral density (BMD) in pediatric subjects with anorexia nervosa.
- Trial name
- NCT00320567
- Testing
- norgestimate/ethinyl estradiol
- Volunteers
- 123 people
- Sponsor
- McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.
Bone Health
Study of the Effect of a Calcium-rich Diet on Bone Health in Girls
The aim of this experimental study was to test the effect of increasing dietary calcium intake to 1500 mg/day on increases in bone quality in adolescent females.
- Trial name
- Calkids (NCT01058109)
- Testing
- calcium-rich diet, Calcium rich diet
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Creighton University
Spinal Cord Injury
Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07418398
- Testing
- Exoskeleton-Assisted Walking (EAW), Active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Breast Cancer, Osteoporosis
Study of Bone Mineral Density in Postmenopausal Women After Treatment for Breast Cancer
Bone Mineral Density (BMD) as measured by X-ray shows the amount of calcium in the bone. Low BMD may reflect osteoporosis, a condition where there is an increased risk of fracture.
- Trial name
- NCT00587925
- Testing
- Bone Mineral Density
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Osteoporosis
Active Rehabilitation in Osteoporotic Patients
The main objective of this study is to target risk factors for falling, such as improved quadriceps muscle strength,balance and bone mineral density (BMD), to reduce the risk of osteoporotic fractures.
- Trial name
- ARO (NCT01357278)
- Testing
- Rehabilitation and patient education
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Hypoparathyroidism, DiGeorge Syndrome
Effects of PTH Replacement on Bone in Hypoparathyroidism
Hypoparathyroidism is a rare condition associated with a low level of parathyroid hormone (PTH) in the blood. Hypoparathyroidism can be genetic and show up in childhood, or it can occur later in life.
- Trial name
- NCT00395538
- Testing
- PTH 1-34
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Healthy, Indicated for EOSedge Imaging
Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA
The purpose of this research is to collect medical imaging data to allow for the comparison of bone mineral density measurements from two different types of low-dose x-ray exams, EOSedge and conventional DXA.
- Trial name
- NCT06659055
- Testing
- DXA Imaging, EOSedge imaging
- Where
- 4 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Alphatec Spine, Inc.
Primary Hyperparathyroidism, Bone Diseases, Metabolic
Radius Loading in Primary Hyperparathyroidism
The purpose of the study is to determine the effect of forearm exercise on forearm bone density in post-menopausal women with or without primary hyperparathyroidism.
- Conditions
- Primary Hyperparathyroidism, Bone Diseases, Metabolic, Osteoporosis, Postmenopausal, Bone Loss, Postmenopausal
- Trial name
- NCT01571843
- Testing
- Forearm exercise program, Walking program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Hyperparathyroidism
The Effects of Alendronate After Cure of Primary Hyperparathyroidism
We are investigating whether, after surgical cure of primary hyperparathyroidism, alendronate provides even greater beneficial skeletal effects than parathyroidectomy alone.
- Trial name
- AlenPostPara (NCT00359385)
- Testing
- Alendronate 70mg weekly
- Where
- United States
- Sponsor
- Columbia University
Spinal Muscular Atrophy Type 3
Whole Body Vibration Therapy in Children With Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) are one of the common physical disabilities in childhood. For SMA, progressive muscle weakness and early fatigue hamper the mobility of the sufferers.
- Trial name
- NCT03056144
- Testing
- whole body vibration therapy
- Where
- Hong Kong
- Volunteers
- 1 people
- Sponsor
- The Hong Kong Polytechnic University
Hip Arthritis
A Migration and Bone Density Study Comparing Hi-Fatigue Bone Cement and Palacos Bone Cement
The purpose of this scientific study is to compare early migration of hip prostheses in respect to the bone in order to determine whether there is a clinical difference between the two investigated bone cements (which one is best…
- Trial name
- NCT01289834
- Testing
- Hi-Fatigue Bone Cement, Palacos Bone Cement
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- University of Aarhus
Sinusitis
The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis
Chronic Rhinosinusitis (CRS) is a common disorder of the nose. The current practice at St Paul's Sinus Centre is to prescribe budesonide via the mucosal atomization device or impregnated saline irrigation.
- Trial name
- NCT03584178
- Testing
- Budesonide via MAD device, Budesonide via intranasals Saline Irrigation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Paul's Hospital, Canada
Inflammatory Bowel Disease
Bone Density in Children With IBD Treated With Amorphous Calcium or Commercial Crystalline Calcium
Patients diagnosed with, or in risk of osteoporosis regularly take calcium dietary supplements, although their contribution to BMD maintenance, prevention of bone loss or reduction of the risk of fracture is questionable.
- Trial name
- NCT02470663
- Testing
- DENSITYTM caplets (marketed as Amorphical), Calcium carbonate 600 mg once daily
- Sponsor
- Sheba Medical Center
Osteopenia Of Prematurity
A Preliminary Study of Bone Density in Neonates
The study is to measure how dense or solid the infant's bones are using a new ultrasound machine and how that density changes over time.
- Trial name
- NCT00631397
- Testing
- Ultrasound machine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cushing Syndrome
Long Term Post Operative Follow-Up of Cushing Syndrome
Although most patients with hypercortisolism can be diagnosed and treated the long-term effects of hypercortisolism and its treatment are unknown. This study will attempt to answer the following questions: 1.
- Trial name
- NCT00029952
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Rotator Cuff Tears
Cutting-through at the Greater Tuberosity
The investigators evaluated the correlation between cutting-through at the greater tuberosity (GT) just medial to the lateral knotless anchor in arthroscopic suture-bridge rotator cuff repair and the bone mineral density (BMD) of…
- Trial name
- NCT04587180
- Testing
- Arthroscopic suture-bridge rotator cuff repair
- Volunteers
- 95 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Osteoporosis
The Effects of Ibandronate or Teriparatide Therapy on Bone Histology and Biochemical Indices in Patients on Hemodialysis With Low Bone Mineral Density
Hemodialysis patients with low bone density (total hip T-score <-2.5) will be assigned to receive teriparatide (those with histologic confirmation of adynamic bone disease) or ibandronate (subjects with increased osteoclast…
- Trial name
- NCT00446589
- Testing
- ibandronate, teriparatide
- Where
- Greece
- Volunteers
- 19 people
- Sponsor
- Papageorgiou General Hospital
HIV
Effect of a Non-tenofovir, Non-efavirenz-based HIV Regimen on Bone Density and Vitamin D Levels in African-American Patients With HIV Infection
2. Objectives 1. To determine the vitamin D status of African-American HIV patients who are HIV-treatment naïve. 2. To compare the effects of an efavirenz-containing regimen to a protease inhibitor regimen on 25-hydroxyvitamin D…
- Trial name
- NCT01343225
- Testing
- atripla, darunavir ritonavir raltegravir
- Volunteers
- 40 people
- Sponsor
- East Carolina University
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
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