Clinical trials: Bone Resorption
Vascular Anomaly, Generalized Lymphatic Anomaly
Identification of Biomarkers for Patients with Vascular Anomalies
The study will use blood (serum and plasma) and tissue obtained from participants undergoing prescribed surgical resection of vascular anomalies of interest proposed in this study.
- Conditions
- Vascular Anomaly, Generalized Lymphatic Anomaly, Kaposiform Hemangioendothelioma, Kaposiform Lymphangiomatosis
- Trial name
- NCT03001180
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Bone Resorption, Symptoms
Microsurgery Using a Bioceramic Root End Filling Material
Endodontic failures are not uncommonly encountered despite improvements in routine root canal therapy. Endodontic microsurgery is one way to manage such failure.
- Trial name
- microsurgery (NCT03733938)
- Testing
- endodontic microsurgery
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Jordan University of Science and Technology
Malocclusion, Angle Class II, Division 1
Efficacy of Injectable Platelet Rich Fibrin (i-PRF) in Enhancing Bone Quality
Twenty patients need therapeutic extraction of the maxillary first premolars with subsequent retraction of the maxillary canines, will be divided randomly into two groups, and will randomly assigned to one side of the maxillary…
- Trial name
- NCT03399760
- Testing
- i-PRF, canine retraction
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Angle Class I
Root Resorption and Alveolar Bone in the Maxillary Canine Retraction Using Injectable Platelet-rich Fibrin: A Split-Mouth Trial
Prolonged orthodontic treatment is a risk factor for root resorption, so accelerating the speed of tooth movement using different methods can limit tooth root resorption.
- Trial name
- NCT06634888
- Testing
- Injectable platelet rich fbirin
- Where
- Vietnam
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Osteopenia, Osteoporosis
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation
This is a Phase 2, open-label, randomized, controlled clinical study of pediatric subjects treated with pamidronate with calcium and vitamin D versus calcium and vitamin D alone following hematopoietic cell transplantation (HCT).
- Trial name
- NCT02074631
- Testing
- Pamidronate, Calcium and vitamin D
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Alveolar Bone Loss
Minimally Invasive Ridge Splitting Versus the Conventional Open Flap Technique
The goal of this clinical trial is to compare implant stability, and crestal bone loss, when using minimal invasive ridge splitting versus convenient open flap technique.
- Trial name
- NCT06329362
- Testing
- Minimally invasive implantation, Open flap procedure for ridge expansion.
- Where
- 2 sites in Egypt, Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Royal College of Surgeons of Edinburgh
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Use of Hyaluronic Acid as a Therapeutic Strategy for Bone Repair in Human
The aim of this study is to evaluate the effects of hyaluronic acid (HA) on bone healing in human dental sockets.
- Trial name
- NCT02709525
- Testing
- hyaluronic acid
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Osteoporosis
Thai Traditional Massage Increases Biochemical Marker of Bone Formation in Postmenopausal Women
To investigate the skeletal effect of Thai traditional massage by examining the changes in biochemical markers of bone turnover.
- Trial name
- NCT01627028
- Testing
- Thai traditional massage
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Angle Class I, Alveolar Bone Loss
Friction or Frictionless: What is the Most Effective Method for Retracting Anterior Teeth?
Objective:To evaluate the effectiveness of the friction (sliding mechanism with elastomeric chains) and frictionless (T-loop) methods for retracting anterior teeth in Angle Class I malocclusion.
- Trial name
- Lam Le Nguyên (NCT06928896)
- Testing
- This interventional trial enrolled a total of 42 patients, dividing them into two age groups: group 1. Using the friction and group 2. Using the frictionless
- Where
- Vietnam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Lumbar Intervertebral Disc Displacement, Cervical Intervertebral Disc Displacement
Disc Resorption in Lumbar and Cervical Disc Herniation Patients Receiving Integrative Korean Medicine Treatment
Measurement of herniated disc resorption and assessment of satisfaction regarding post-treatment state and integrative Korean medicine treatment through phone interview in 500 patients with MRI follow-up results receiving…
- Trial name
- NCT02841163
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 505 people
- Sponsor
- Jaseng Medical Foundation
Alveolar Bone Resorption, Alveolar Bone Grafting
Split Crest Procedure: Is It Necessary to Fill the Gap?
This prospective controlled clinical study evaluates the effectiveness of adding bone graft or dentin graft material during the split crest (alveolar ridge splitting) procedure for horizontal ridge augmentation with simultaneous…
- Conditions
- Alveolar Bone Resorption, Alveolar Bone Grafting, Bone Expansion
- Trial name
- NCT07272694
- Testing
- Split Crest Technique
- Where
- Serbia
- Volunteers
- 24 people
- Sponsor
- Vladimir Biocanin
Osteoporosis
Assessment of Anti-RANKL Antibody in Post-menopausal Women
This is a single-center, open-label, dose-escalating study to evaluate the safety, pharmacokinetics, immunogenicity, and preliminary efficacy of single dose subcutaneous injection of a fully human monoclonal antibody of receptor…
- Trial name
- NCT03242512
- Testing
- TK006
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu T-Mab Biopharma Co.,Ltd
Fatigue, Inflammation
Effects of Post-exercise Protein Supplementation in Young Athletes
This randomised double blind, placebo-controlled study examined the effects of post-exercise consumption of whey protein (PRO) or carbohydrate (CHO) on performance recovery, muscle damage and inflammatory cytokine responses…
- Conditions
- Fatigue, Inflammation, Bone Resorption
- Trial name
- NCT04114045
- Testing
- Experimental:Whey protein, Active Comparator: Isoenergetic control - Carbohydrate
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brock University
Root Resorption, Orthodontic Appliance
Three-dimensional CBCT Analysis of Root Volume Changes Following Tooth-bone and Bone-borne Maxillary Expansion: A Pilot Study.
External root resorption (ERR) is an undesired side effect observed after rapid maxillary expansion (RME). This study aimed to investigate changes in the root volume of maxillary permanent first molars after RME using tooth-borne…
- Conditions
- Root Resorption, Orthodontic Appliance, CBCT Segmentation
- Trial name
- NCT06912568
- Testing
- Miniscrew insertion, Expander, CBCT
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Bone Resorption
Using Platelet Rich Plasma in Reducing Alveolar Bone Resorption During Rapid Maxillary Expansion
The purpose of this study is to determine if the injection of Platelet-rich plasma (PRP) is effective in reducing alveolar bone loss that happens after each rapid maxillary expansion (RME) on the buccal aspect of the posterior…
- Trial name
- NCT03028038
- Testing
- Platelet Rich Plasma, No Platelet Rich Plasma
- Where
- Syria
- Volunteers
- 16 people
- Sponsor
- Damascus University
Clift Lip, Cleft Palate
Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone)
Study Objective The objective of this study was to evaluate and compare postoperative pain and hospital costs in pediatric patients with cleft lip and palate undergoing alveolar bone grafting surgery.
- Conditions
- Clift Lip, Cleft Palate, Alveolar Bone Loss, Postoperative Pain
- Trial name
- NCT07734974
- Testing
- Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Bone Resorption
Dietary Intake Modifications to Protect Against Changes in Bone Metabolism
Bone loss is not only a well-documented effect of spaceflight on astronauts, but also a condition that affects millions of men and women on Earth each year.
- Trial name
- ProK (NCT01713634)
- Testing
- Preflight, In-flight
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)