Clinical trials: Borderline Personality Disorders
Self Harm, Borderline Personality Disorder
Predictors of Clinical Course and Treatment Response in DBT Programmes
The project is a collaboration between The National Centre for Suicide Research and Prevention (NSSF) and clinical units with Dialectical Behaviour Therapy (DBT) programmes.
- Trial name
- NCT04318899
- Testing
- Dialectical Behaviour Therapy adapted for adolescents (DBT-A), Dialectical Behaviour Therapy - Standard version (DBT)
- Where
- 5 sites in Norway
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Borderline Symptoms, Borderline Personality Disorder
The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents
The goal of this randomized and controlled trial is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms.
- Trial name
- NCT06606002
- Testing
- Group schema therapy, Treatment as Usual (TAU)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Self-Harm, Deliberate, Suicidal Behavior
Intensive Dialectical Behavior Therapy for Self-Harm and Suicidal Behavior in Youth: A Pilot Study
The prevalence of self-harm and suicidal behavior among adolescents has increased dramatically over the past two decades-a fourfold rise that represents both a severe personal burden and a substantial public health challenge.
- Conditions
- Self-Harm, Deliberate, Suicidal Behavior, Borderline Personality Disorder (BPD)
- Trial name
- NCT07450105
- Testing
- Intensive Dialectical Behavior Therapy
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Haukeland University Hospital
Borderline Personality Disorder, Sleep Disturbance
Real-time Experiences With Sleep Training Study
Borderline personality disorder (BPD) is a serious mental illness that often first emerges in adolescence. Effective treatments are typically expensive, lengthy, and intense (e.g., Dialectical Behavior Therapy).
- Trial name
- REST (NCT04507308)
- Testing
- Single-session sleep intervention drawn from principles of the TSC-youth protocol
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- University of Utah
Treatment 1:Dialectical Behavior Therapy (DBT), Treatment as Usual
Efficacy of "DBT-LIVE", an Identity Skills Training Program, for Borderline Personality Disorder.
The main objective of this project is to adapt and evaluate the LIVE Skill module in the Spanish population. LIVE Skill is a psychological intervention protocol specifically designed to address identity disturbances in…
- Trial name
- NCT07684872
- Testing
- DBT LIVE, TAU
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Universidad Europea de Valencia
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Adolescent - Emotional Problem, Personality Disorders in Adolescence
Representations of the Body's Interior in Adolescence
Representations of the inner body in adolescence: developmental characteristics and specificities in borderline personality disorders.
- Conditions
- Adolescent - Emotional Problem, Personality Disorders in Adolescence, Body Representation, Borderline Personality Disorder
- Trial name
- RICA (NCT07407764)
- Testing
- Drawing of the inside of the body, interviews and questionnaires.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Borderline Personality Disorder (BPD)
Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT06675461
- Testing
- Gold Card Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder
Short Integrative And Neurocognitive Therapy For Young Adults With Borderline Personality Disorder
Borderline personality disorder (BPD) is a severe, high-suicidal psychiatric disorder associated with impulsive, endangering behaviors.
- Trial name
- SINTYA (NCT05913544)
- Testing
- SINTYA
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Borderline Personality Disorder
rTMS-enhanced Psychotherapy for Borderline Personality Disorder
This project assesses the effectiveness and lasting impact of combining Dialectical Behavioral Therapy (DBT) with prefrontal repetitive transcranial magnetic stimulation (rTMS) in patients with borderline personality disorder.
- Trial name
- rTMS-DBT (NCT06259851)
- Testing
- Dialectical behavioral therapy program, Prefrontal rTMS treatment
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Masarykova Univerzita
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Borderline Personality Disorder
MBT-early: a Single Case Experimental Design
Borderline personality disorder (BPD) is characterized by problems in emotion regulation, identity disturbances, and impaired interpersonal functioning.
- Trial name
- NCT06212024
- Testing
- Mentalization Based Treatment-early
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- De Viersprong
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Personality Disorder
Neural Mechanisms of Dialectical Behavioral Therapy in Patients with Borderline Personality Disorder
This research examines the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD).
- Trial name
- NeuroDBT (NCT06882330)
- Testing
- Dialectical behavior therapy
- Where
- Czechia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Masarykova Univerzita
Borderline Personality Disorder, Adolescent Development
Emotional Regulation and Impulsivity Among Adolescents with Borderline Personality Disorder
This study aims to better understand the behavioral, neurobiological and hormonal underpinnings of stress and reward reactivity of adolescents suffering from borderline personality disorder compared to healthy adolescents by a…
- Trial name
- ADOLIMIS (NCT03209102)
- Testing
- Clinical assessment, Stress elicitation experiment, Structural and Functional MRI
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder in Adolescence
Dialectical Behavior Therapy for Adolescents at Rutgers University
This project expands our existing psychological services clinic (the Dialectical Behavior Therapy Clinic at Rutgers University; DBT-RU) to include an adolescent treatment arm.
- Trial name
- NCT03861858
- Testing
- DBT-A
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Rutgers, The State University of New Jersey
Borderline Personality Disorder
The BRIDGE Project
The BRIDGE project: A feasibility randomised controlled trial of brief, intensive assessment and integrated formulation for young people (age 14-24) early in the course of borderline personality disorder.
- Trial name
- BRIDGE (NCT05023447)
- Testing
- BRIDGE Intervention, Service as Usual
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS Greater Glasgow and Clyde
Personality Disorders
Biological Effects of Schema Therapy
Background: The major aim of this study is to compare the effects of emotion focused (experiential) and cognitive interventions of schema therapy (ST) on emotion regulation deficits in patients with borderline personality…
- Trial name
- BE-ST (NCT06367907)
- Testing
- schema therapy
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital