Clinical trials: Brain Infarction
Cardiovascular Diseases, Coronary Disease
Observational Aspirin Use and CVD in the Physicians' Health Study
To analyze existing data from the Physicians Health Study (PHS), a randomized primary prevention trial of low-dose aspirin and beta carotene conducted among 22,071 U.S.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00005493
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Congenital Hemiparesis
Comparing the Location of the Motor Cortex in Children Using Two Methods
Hypothesis: In typically developing children (TDC), use of conventional EEG landmarks to determine the brain area that controls hand function will not differ from TMS-guided determination of individual motor hotspots.
- Trial name
- NCT02015338
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Heart Diseases
Evans County Studies
To conduct surveillance of cardiovascular morbidity and mortality and its correlation with known risk factors in all cohort study groups in Evans County, Georgia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Angina Pectoris
- Trial name
- NCT00005122
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Cerebrovascular Accident
Homocyst(e)Ine, Vitamin Status, and CVD Risk
To test the hypotheses that the risk of myocardial infarction and/or stroke is associated with elevated plasma levels of homocysteine, and low plasma levels of folate, vitamins B12 and B6.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005482
- Sponsor
- University of Washington
Cerebral Amyloid Angiopathy, Small Vessel Cerebrovascular Disease
Prognosis of Cerebral Small Vessel Disease
Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study is to determine the risk of different outcome events among patients…
- Conditions
- Cerebral Amyloid Angiopathy, Small Vessel Cerebrovascular Disease, Cadasil, CAA - Cerebral Amyloid Angiopathy
- Trial name
- PRO-SVD (NCT05734378)
- Where
- Switzerland
- Volunteers
- 900 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiovascular Diseases, Diabetes Mellitus
Nurses' Health Study (Cardiovascular Component)
To determine the relationships of hormonal, reproductive, dietary, and lifestyle factors, as well as biochemical and genetic factors, with the subsequent risk of coronary heart disease and other cardiovascular events in a cohort…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Coronary Disease, Heart Diseases
- Trial name
- NCT00005152
- Volunteers
- 121,700 people
- Sponsor
- Brigham and Women's Hospital
Antiplatelet Therapy, Hemorrhagic Infarction
Early Antiplatelet Therapy After Hemorrhagic Infarction in Acute Ischemic Stroke Treated With Intravenous Thrombolysis (HITs)
Previous study showed that the proportions of hemorrhagic Infarction after intravenous thrombolysis were 24.2% and 32.5% in the control group and the alteplase group, and most of them were asymptomatic.
- Trial name
- NCT04624295
- Testing
- Early aspirin Therapy, Non-Early aspirin Therapy
- Where
- China
- Volunteers
- 294 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Infarction, Anterior Cerebral Artery, Infarction, Middle Cerebral Artery
An Observational Registry Study of LUOTAI in Patients With Acute Ischemic Stroke in Vietnam
Ischemic stroke occurs when an artery to the brain is blocked. If the artery remains blocked for more than a few minutes, the brain cells may die. This is why immediate medical treatment is critical.
- Conditions
- Infarction, Anterior Cerebral Artery, Infarction, Middle Cerebral Artery, Ischemic Attack, Transient
- Trial name
- NCT03679364
- Where
- 3 sites in Vietnam
- Volunteers
- 364 people
- Sponsor
- KPC Pharmaceuticals, Inc
Cardiovascular Diseases, Heart Diseases
Novel Hemostatic Cardiac Risk Factors in Framingham
To investigate hemostatic variables in relation to cardiovascular risk in the Framingham Offspring Study cohort.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Death, Sudden, Cardiac, Myocardial Infarction
- Trial name
- NCT00005356
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Heart Diseases
Mortality Follow-Up and Analyses of Men in the MRFIT
To extend mortality followup through 25 years for two cohorts of men in the Multiple Risk Factor intervention Trial (MRFIT): the 361,662 men screened and the 12,866 men randomized, and to pursue the general aim of elucidating…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Ischemia
- Trial name
- NCT00011206
- Sponsor
- University of Minnesota
Apoplexy, Femoral Neck Fracture
Epidemiology of Aeromedical Evacuation
Increasing air travel has resulted in a significant increase in aeromedical evacuation over the past decade. However there is only a small amount of epidemiological data available on the diagnosis, costs and transport…
- Conditions
- Apoplexy, Femoral Neck Fracture, Myocardial Infarction, Subarachnoid Hemorrhage
- Trial name
- NCT01071382
- Volunteers
- 504 people
- Sponsor
- Ruhr University of Bochum
Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP)
Oral Care Strategies for Stroke Patients with Dysphagia
This study aims to evaluate whether combining neuromuscular electrical stimulation (NMES) with oral care can improve swallowing function in patients who have experienced an acute stroke and are dealing with dysphagia (difficulty…
- Conditions
- Acute Ischemic Stroke (AIS), Stroke-Associated Pneumonia (SAP), Dysphagia Following Cerebrovascular Accident
- Trial name
- NCT06692101
- Testing
- oral care, Neuromuscular Electrical Stimulation (NMES)
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Collateral Circulation, Large-artery Occlusion
Study of Collateral Circulation in Patients With Symptomatic Intracranial Anterior Circulation Occlusion
Intracranial artery stenosis is the leading cause of stroke onset or recurrence in Asian. Multiple studies have shown that anterior circulation is most common in intracranial artery stenosis, especially the middle cerebral artery…
- Conditions
- Collateral Circulation, Large-artery Occlusion, Cerebral Infarction
- Trial name
- NCT04091412
- Testing
- Butylphthalide Soft Capsules
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Hebei Medical University
Sickle Cell Anemia, Stroke
Silent Cerebral Infarct Transfusion Multi-Center Clinical Trial
The goal of this study is to determine the effectiveness of blood transfusion therapy for prevention of silent cerebral infarct (stroke) in children with sickle cell anemia.
- Trial name
- SIT (NCT00072761)
- Testing
- transfusion therapy
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Washington University School of Medicine
Cardiovascular Diseases, Heart Diseases
Minnesota Heart Health Program
To conduct a large-scale community-based demonstration and education research project designed to evaluate the effectiveness of multiple educational strategies on risk factor reduction and the primary prevention of…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- NCT00005150
- Sponsor
- University of Minnesota
Stroke, Stroke Acute
Mechanical Thrombectomy in the Middle East and North Africa: Interim Results from the MEMENTO Registry
The MEMENTO (MEchanical thrMobectomy NETwork for MENA TOgether) Registry is a multicenter, prospective observational study aiming to evaluate the effectiveness, safety, and cost-effectiveness of mechanical thrombectomy (MT) in…
- Conditions
- Stroke, Stroke Acute, Endovascular Procedures, Large Vessel Occlusion
- Trial name
- MEMENTO Regist (NCT06702787)
- Where
- Egypt
- Volunteers
- 1,500 people
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Sturge - Weber Syndrome (SWS)
Developing a Tailored Neuropsychological Rehabilitation for Sturge-Weber Syndrome
The goal of this observational study is to learn about the neuropsychological profile of Sturge-Weber Syndrome (SWS) in children and adults with this rare neurocutaneous condition.
- Trial name
- NPS-SWS (NCT07655492)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Anemia, Sickle Cell, Blood Disease
Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center
To conduct a prospective study aimed at the early detection and treatment of cerebral vascular disease prior to irreversible brain injury in young children with sickle cell anemia (SCA).
- Conditions
- Anemia, Sickle Cell, Blood Disease, Cerebrovascular Disorders, Cerebrovascular Accident
- Trial name
- NCT00005327
- Sponsor
- University of Southern California