Clinical trials: Brain Infarction
Intracranial Embolism, Thrombosis
Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion
The purpose of the present, randomized, controlled multicenter phase III trial is to investigate the safety and efficacy of continuous 1-hour insonation of occluded middle cerebral artery with 2 MHz TCCS in stroke patients…
- Trial name
- NCT00336596
- Testing
- transcranial ultrasound in patients treated with iv t-PA
- Where
- 6 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Cardiovascular Diseases, Peripheral Vascular Diseases
Homocysteine and Progression of Atherosclerosis
In the first phase, to establish the relationship of progression of peripheral vascular disease (PVD) to plasma homocysteine. In the second phase, to conduct a randomized, controlled trial of folic acid treatment of plasma…
- Conditions
- Cardiovascular Diseases, Peripheral Vascular Diseases, Atherosclerosis, Cerebrovascular Disorders
- Trial name
- NCT00005338
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cerebral Infarction
Early Determinants of Multidimensional Outcome at School Age After Neonatal Arterial Ischemic Stroke
While perinatal ischemic stroke is the most frequent form of childhood stroke, early determinants of outcome remain poorly understood.
- Trial name
- NCT02511249
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pediatric Cerebral Stroke, Brain Infarction/Diagnosis
Role of Advanced Magnetic Resonance Imaging in Assessment of Pediatric Cerebral Stroke
Stroke can be ischemic, hemorrhagic, or both. Early recognition and treatment of pediatric stroke are critical in optimizing long-term functional outcomes, reducing morbidity and mortality, and preventing recurrent stroke.
- Trial name
- NCT03617159
- Testing
- Magnetic Resonance Imaging
- Volunteers
- 68 people
- Sponsor
- Assiut University
Cerebral Infarction
Study on Yangxue Nao Granules Reducing the Risk of Stroke
Objective: To explore the effectiveness of raising serum nao granules in reducing the risk of bleeding in patients with acute ischemic stroke treated with intravenous thrombolysis in the real world
- Trial name
- NCT04949906
- Testing
- Raise serum brain granules, No nourishing serum brain granules are used
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Rehabilitation of Upper Limb Motor Function in Hemiplegia Due to Supratentorial Cerebral Infarction Using Armeo Power Robot
Effects of Armeo Power Robot Therapy on Upper Limb Recovery in Hemiplegic Stroke Patients
This study investigates the effectiveness of combining Armeo Power robotic therapy with conventional rehabilitation techniques to improve upper limb motor function in patients with hemiplegia caused by supratentorial cerebral…
- Trial name
- BV108/RAPPHCN (NCT06708065)
- Testing
- Armeo Power robot restores upper limb motor function., A Home Exercise Program, Occupational therapy activities
- Where
- Vietnam
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Stroke, Silent Cerebral Infarct
Total Cerebral Protection With Embolic Protection Devices Thoracic Aortic Stenting
Stroke and silent cerebral infarction are a real risk with thoracic enodvascular aortic repair (TEVAR). The investigator propose to prospectively observational study with enrolment of all patients undergoing TEVAR for thoracic…
- Trial name
- NCT04062539
- Testing
- Sentinel and Spider
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London
Sturge- Weber Syndrome
Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome
Sturge-Weber syndrome (SWS) is a rare congenital neuro-cutaneous disorder considered as a rare or orphan disease. SWS is characterized by a capillary vascular malformation (CM) localized on the skin of the face, eyes and central…
- Trial name
- RSW (NCT02080624)
- Testing
- Drug: Topical Rapamycin
- Where
- Spain
- Volunteers
- 23 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Cerebral Infarction
Effect of Sarpogrelate on Platelet Aggregation in Patients With Cerebral Infarction: Dose-responsive Clinical Pharmacology Study
Sarpogrelate is an antiplatelet agent that decreases 5-hydroxytryptamine( 5-HT )levels in platelets via blockade of 5-HT2 receptors, has been used in atherosclerotic peripheral arterial disease.
- Trial name
- NCT00147303
- Testing
- MCI-9042
- Volunteers
- 46 people
- Sponsor
- Tanabe Pharma Corporation
Cardiovascular Diseases, Atrial Fibrillation
Pharmacogenetics and Cardiovascular Events
To assess interactions between selected cardiovascular medications and genes in the incidence of heart attack, stroke, and atrial fibrillation, an irregular heartbeat.
- Conditions
- Cardiovascular Diseases, Atrial Fibrillation, Cerebrovascular Accident, Heart Diseases
- Trial name
- NCT00094198
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Disease, Coronary Heart Disease
Periodontitis and Cardiovascular Events or "PAVE"
The purpose of this study is to determine if treating periodontal infections (gum problems) will lead to fewer heart problems in patients at high risk for cardiovascular disease.
- Conditions
- Cardiovascular Disease, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- NCT00066053
- Testing
- Periodontal Treatment: SRP, Referral
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- University at Buffalo
Cardiovascular Diseases, Heart Diseases
Flavonoids and Cardiovascular Disease
To determine the association between flavonoids intake and the prevention of incident cardiovascular disease (CVD).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Myocardial Infarction
- Trial name
- NCT00006504
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stroke, Ischemic Stroke
Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes
Supernova and Neutron are endovascular mechanical revascularization devices indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing an acute ischemic stroke within 24 hours…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disorders, Brain Diseases
- Trial name
- GRASSROOT Reg (NCT07335185)
- Testing
- Supernova revascularization device
- Volunteers
- 3,000 people
- Sponsor
- Gravity Medical Technology, INC
Ischemic Stroke
Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery
The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.
- Trial name
- NCT00867581
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Stroke, Ischemic Attack, Transient
Impact of Door-to-Needle Time on Stroke Outcomes at Gonesse Hospital
This study looks at how quickly stroke patients receive treatment after arriving at Gonesse Hospital and whether this affects their recovery.
- Conditions
- Stroke, Ischemic Attack, Transient, Cerebral Infarction, Thrombolytic Therapy
- Trial name
- NCT07018167
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier de Gonesse
Stroke
OASIS STUDY Outcome Assessment Using SF-36 v2 in Stroke Patient Study(OASIS STUDY)
1. To survey the health-related quality of life using the SF-36v2 score of patients with chronic brain infarction in Japan 2. Chronic brain infarction in Japan is better than EU/USA
- Trial name
- NCT00281034
- Where
- Japan
- Volunteers
- 2,069 people
- Sponsor
- Kyorin Pharmaceutical Co.,Ltd
Stroke, Cerebrovascular Diseases
An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases
In this protocol, the investigators present methods and preliminary results from the PLATFORM-CVD Study, an EHR-based multicenter cohort.
- Conditions
- Stroke, Cerebrovascular Diseases, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- PLATFORM-CVD (NCT04775836)
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Cardiovascular Diseases, Heart Diseases
Predictors of Cardiovascular Disease in the Elderly
To evaluate factors associated with cardiovascular morbidity and mortality in a cohort of 795 men and women aged 75 years or older at the time of a comprehensive examination conducted between 1984 and 1987.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- NCT00005460
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Kidney Diseases, End-Stage Kidney Disease
Major Outcomes With Personalized Dialysate TEMPerature
People with failed kidneys need an artificial kidney machine (called dialysis) to remove toxins and extra fluid from the body. Most patients receive dialysis treatments at a hospital three times a week.
- Conditions
- Kidney Diseases, End-Stage Kidney Disease, Hemodialysis
- Trial name
- MyTEMP (NCT02628366)
- Testing
- Personalized Dialysate Temperature
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Carotid Atherosclerosis, Myocardial Infarction
Comparison of Asymptomatic Carotid Atherosclerosis Between Frequent and Infrequent Blood Donors
Iron has been proposed to contribute to atherogenesis in humans by facilitating the oxidation of lipoproteins. This observational study will evaluate the association between frequency of blood donation - expected to be associated…
- Trial name
- NCT00001589
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)