Clinical trials: Brain Lesion
Brain Injury Traumatic Severe, Intracranial Hemorrhage, Hypertensive
Multiomic Analysis of Traumatic Brain Injury and Hypertension Intracranial Hemorrhage Lesion Tissue
The goal of this experimental observation study is to figure out differently expressed biomarkers in lesion tissues in traumatic brain injury or hypertension intracranial hemorrhage patients.
- Trial name
- MOSS-THINK (NCT05778110)
- Testing
- Type of disease
- Where
- China
- Volunteers
- 10 people
- Sponsor
- RenJi Hospital
Carotid Artery Stenosis
Gao's Triple Eversion Carotid Endarterectomy
Carotid endarterectomy (CEA), an important surgical approach for managing carotid plaque, has evolved over more than 70 years but still cannot be applied to all tandem carotid lesions (TCLs) because of the wide range of these…
- Trial name
- NCT06722222
- Testing
- Gao's triple eversion carotid endarterectomy
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypothalamic-pituitary Lesions, Craniopharyngiomas
Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions
In children treated for intracranial lesions, the 2 factors of the obesity are : the location of the lesion (hypothalamic-pituitary region) and craniopharyngiomas
- Trial name
- NCT00306683
- Testing
- DIAZOXIDE
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Brain Diseases, Amblyopia
MRI-based Biomarkers for Predicting Punctate White Matter Lesions in Neonates
As a common white matter (WM) disease in preterm neonates, punctate white matter lesion (PWML) frequently leads to the abnormalities of brain development (e.g.
- Conditions
- Brain Diseases, Amblyopia, Brain Damage, Chronic, Cerebral Palsy
- Trial name
- PWML (NCT02637817)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cerebral Palsy
Whole Body Vibration in Rehabilitation of Spastic Cerebral Palsy
Spasticity is one of the most common features in children with cerebral palsy (CP) and is evident in the majority of CP types such as hemiplegia, diplegia, quadriplegia, etc.
- Trial name
- WBV (NCT06077136)
- Testing
- whole body vibration, standard physical therapy
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- University of Hail
Brain Lesions
To Investigate the Event Related Potentials (ERPs) of Patients With Brain Lesions
Event-related potentials (ERPs）has the advantage of excellent temporal resolution on measuring real-time neural activities that reflect to higher level cognitive processes.
- Trial name
- NCT01254500
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Fabry Disease
Pulsatility Index, Vasomotor Reactivity and Leukoencephalopathy in Fabry Patients
We hypothesize that Fabry disease - FD is associated with elevated vascular resistance induced by cerebral small-vessel disease, indicating increased distal resistance to blood flow.
- Trial name
- NCT04577170
- Testing
- Transcranial Doppler (TCD) and Transcranial Color-Coded Duplex (TCCD) ultrasonography
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Amblyopia, Binocular Vision Disorder
A Patch Free Treatment for Young Children With Amblyopia
The purpose of this study is to test whether a binocular treatment can improve vision and motor function in young children with amblyopia.
- Trial name
- NCT04086524
- Testing
- Binocular cartoon treatment at home, Patching, Binocular cartoon treatment in office
- Where
- 2 sites in United States, Australia
- Volunteers
- 34 people
- Sponsor
- University of Waterloo
Amblyopia
The Role of Interactive Binocular Treatment System in Amblyopia Therapy
Purpose: of determining the role of Interactive Binocular Treatment (I-BiTTM) as a complementary method of patching in amblyopia therapy.
- Trial name
- NCT02740725
- Testing
- Patching Therapy, Interactive Binocular Treatment System
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Idiopathic Parkinson Disease
Transdermal Rotigotine User Surveillance Study
This study will be conducted in an observational multiple-cohort design aimed at acquiring clinical, treatment, health status, and economic data. Patients with Parkinson's disease (PD) will be enrolled.
- Trial name
- TRUST (NCT00599339)
- Where
- 211 sites in Czechia, Denmark and 8 more
- Volunteers
- 2,195 people
- Sponsor
- UCB Pharma
Epilepsy
Sensor-Dot and Plug 'n Patch Study in Epilepsy
The investigators plan to determine whether it is possible to use a small, unobtrusive wearable device (the Sensor Dot with Plug 'n Patch system) to follow-up epilepsy in the home environment through measurement of different…
- Trial name
- NCT04642105
- Testing
- Sensor-Dot and Plug 'n Patch system
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Stroke
Biodiversity and Human Functioning Following Acquired Cerebrovascular Lesions - Phase 1
The study aims to investigate the impact that the set of factors to which a post-stroke person is exposed during daily life can have on their health.
- Trial name
- EspertaMente (NCT07504692)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Dr. Franco Molteni
Post-Dural Puncture Headache
The Occurrence of Post Dural Puncture Headache After Epidural Blood Patch
Spinal anesthesia is commonly used for cesarean section.However, the procedure is still have some adverse events such as high spinal block, nerve injuries or postdural puncture headache (PDPH).This is a potential complication of…
- Trial name
- NCT03080610
- Where
- 2 sites in Thailand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Neuroepithelial Cyst
Assessment of the Efficacy of Stereotactic Intracavitary Instillation of 90Yttrium Colloid
Neuroepithelial cysts are rare, representing less than 1% of the intracranial cysts. Neuroepithelial cysts, are benign and mostly asymptomatic. These cysts are lined by thin columnar or low cuboidal epithelium.
- Trial name
- NCT04758104
- Testing
- Yttrium90
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- David Clarke
Posterior Fossa Lesion
Comparison of Surgical Outcomes of Craniotomy and Craniectomy in Posterior Fossa Lesions
The purpose of this randomized controlled trial is to compare the surgical outcomes of craniotomy and craniectomy among patients with posterior fossa lesions.
- Trial name
- NCT06831695
- Testing
- Craniotomy, Craniectomy
- Volunteers
- 80 people
- Sponsor
- University of Health Sciences Lahore
Medulloblastoma, Childhood, Healthy Volunteers
Child's Study of the Impact of PF Lesion on Motor Skills, Language, Cognitive Functioning and Social Cognition
One of the major complications of posterior fossa surgery is Posterior Fossa Syndrome (PFS). This syndrome is due to a possible complication of surgical excision of a tumor of the cerebellum (4th ventricle) and is characterized…
- Conditions
- Medulloblastoma, Childhood, Healthy Volunteers, Fossa Posterior Tumor, Low-grade Glioma
- Trial name
- CervIRM (NCT04174820)
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- 5 sites in France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers