Clinical trials: Brain Modulation
Epilepsy, Sensory Modulation Disorder
Sensory Modulation in Children With Epilepsy
Epilepsy is a neurological condition that can impact cognitive, motor, and behavioral skills, often leading to sensory modulation disorders (SMDs) in children.
- Trial name
- NCT06818344
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Stress Disorder, Post Traumatic
Benefits of Relaxation by Music Therapy on PTSD Symptoms
PTSD is a debilitating mental disorder that may develop after experiencing or witnessing a life-threatening event. With appropriate care, treatment efficiency is variable and around 20% of the patients do not respond to…
- Trial name
- TRACER (NCT03990064)
- Testing
- musicotherapy
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Institut de Recherche Biomedicale des Armees
Cerebral Palsy (CP), Typically Developing Children
The Effect of Perturbation Training on Reactive Balance in Children With Cerebral Palsy
The aim of this project was to evaluate whether perturbation training influences reflex modulation in children with spastic CP and whether changed reflex modulation leads to improved reactive balance and walking.
- Trial name
- NCT07818928
- Testing
- Balance training on a moving platform
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy
Modulation of Sagittal Spinal Geometry in Children With Cerebral Palsy
The aim of this study will be to evaluate the the effect of Thera Togs soft orthotic undergarment on modulation of the spinal geometry and mobility in sagittal plan in children with spastic diplegic cerebral palsy.
- Trial name
- NCT04271618
- Testing
- TheraTogs Orthotic Undergarment
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Parkinson's Disease
Dopaminergic Modulation of Declarative Memory
The study investigates the effect of dopaminergic stimulation over declarative memory functions in Parkinson's disease (PD) patients.
- Trial name
- NCT03151460
- Testing
- Dopamine Agent
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Dystonia, Dystonic Cerebral Palsy
Enhancing Sensorimotor Processing in Children With Dystonia
Dystonia is a severely disabling movement disorder with no cure, in which people suffer painful muscle spasms causing twisting movements and abnormal postures. There are many causes, including genetic conditions and brain injury.
- Conditions
- Dystonia, Dystonic Cerebral Palsy, Dystonia, Secondary, Dystonia, Primary
- Trial name
- NCT05612464
- Testing
- No intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- King's College London
Growth Hormone Deficiency
Gene Expression in Monocytes of Growth Hormone Deficient Children
The Growth hormone (GH) is mainly synthesized in the anterior portion of the pituitary gland and has an effect on different body areas.
- Trial name
- GEMGH (NCT04352712)
- Testing
- blood sampling
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Salerno
Functional Neurological Symptom Disorder, Neurological Diseases or Conditions
Modulation of Sense of Agency With Non-invasive Brain Stimulation and Mindfulness-based Stress Reduction Therapy
A conversion disorder is a dysfunction of the nervous system in which no structural damage can be demonstrated. However, it must be distinguished from other psychiatric disorders such as psychosis or depression.
- Trial name
- NCT05086380
- Testing
- Mindfulness-based stress reduction therapy, Inhibitory TMS, Psychoeducation
- Where
- Switzerland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Hyperopia, Amblyopia
Effect of Peripheral Defocus on Axial Growth in Hyperopes
Hyperopia, also known as farsightedness, is a common type of refractive error where distant objects may be seen more clearly than objects that are near.
- Conditions
- Hyperopia, Amblyopia, Anisohyperopia
- Trial name
- NCT02686879
- Testing
- Multifocal contact lenses, Single vision contact lenses
- Where
- 2 sites in United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aston University
New Daily Persistent Headache (NDPH)
Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children
New daily persistent headache (NDPH) is a primary headache disorder characterized by the daily and unremitting headache pain patients experience with a distinct onset.
- Trial name
- EMCS-NDPH (NCT03447782)
- Testing
- Naltrexone HCl (Bulk) Powder
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Stress Physiology
Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress
Emerging evidence supports the existence of a microbiota-gut-brain axis through which gut microbes influence cognition, mood and behavior.
- Trial name
- NCT05392556
- Testing
- Probiotic, Prebiotic
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Healthy
Oral Oxytocin Modulation of Responses to Emotional Stimuli
The main aim of the study is to investigate whether orally administered oxytocin (24IU) can modulate neural and behavioral responses to positive and negative valence stimuli during basal (emotional scenes) and higher order…
- Trial name
- NCT04320706
- Testing
- Oral Oxytocin
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Alzheimer's Disease, Healthy
The Effect of Acetylcholine on Memory and Attention
This study will examine whether enhancing the chemical acetylcholine in the brain can improve memory and attention. It will identify changes in brain function that occur during these cognitive tasks.
- Trial name
- NCT00001977
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Stroke, Healthy
Effects of Flumazenil on Brain Excitability
This study will investigate the effects of the drug flumazenil on brain excitability and the drug's relationship to a natural brain chemical called GABA.
- Trial name
- NCT00015678
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)