Clinical trials: Brain to Brain Communication
GNAO1, Dystonia
Prospective Pilot Trial to Address Feasibility and Safety of Oral Zinc in GNAO1 Associated Disorders
The goal of this clinical trial is to investigate feasibility and safety of an oral therapy with zinc in patients affected by Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1) associated disorders.
- Conditions
- GNAO1, Dystonia, Epilepsy, Development Delay
- Trial name
- ZINCGNAO1 (NCT06412653)
- Testing
- Zinc Acetate Dihydrate
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Children's University Hospital Cologne, Germany
Term Infant, Late Preterm Infant
Brain Uptrain to Improve Learning and Development
The purpose of this study is to see if an early literacy and developmental program in addition to shared reading can increase developmental test scores at 24 months of age.
- Trial name
- BUILD (NCT06638801)
- Testing
- Coach-led caregiver-implemented early literacy and developmental programming, Reach Out and Read Training
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Alabama at Birmingham
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Attention Deficit Hyperactivity Disorder, Asthma
Using an Online Patient Monitoring System to Improve Care for Children With Chronic Conditions
TriVox Health is an online system designed to make it easy for healthcare providers to monitor patients' disease symptoms and functioning over time and in between in-person visits (http://www.youtube.com/watch?v=VR1vcbx0Ef4).
- Conditions
- Attention Deficit Hyperactivity Disorder, Asthma, Autism Spectrum Disorder, Depression
- Trial name
- TriVoxHealth (NCT02097355)
- Testing
- TriVox for clinical care
- Where
- United States
- Volunteers
- 946 people
- Sponsor
- Boston Children's Hospital
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Cerebral Palsy, Dysarthria
Speech Motor Treatment in Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor disability worldwide, with a prevalence of 2-2.5 per 1000 live births. Children with CP may experience a variety of difficulties with communication including speech.
- Trial name
- NCT04189159
- Testing
- PROMPT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Fondazione Stella Maris
Prader-Willi Syndrome
Follow-up of Prader Willi Syndrome Infants Treated by Oxytocin and Comparison With Not-treated Infants.
The objective of this study is to collect data on tolerance and effects of early treatment with oxytocin in children with Prader Willi Syndrome aged from 3 to 4 years and to compare these infants with not treated age-matched…
- Trial name
- OT2SUITE (NCT03081832)
- Testing
- Oxytocin, Control
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Developmental Dyscalculia
tRNS Combined to Cognitive Training in Children With Dyscalculia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyscalculia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT04242680
- Testing
- Brainstim DLPFC, Brainstim PPC, Cognitive Training
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Refractive Errors, Amblyopia
Performance of 2WIN Photoscreener With Corneal Reflex Compared to School Bus Retinoscopy by AAPOS Guidelines
Pediatric eye patients receive infrared photoscreener screening and skiascopy as a part of routine examination to compare ability to detect amblyopia risk factors.
- Conditions
- Refractive Errors, Amblyopia, Strabismus, Development Delay
- Trial name
- 2WINbus (NCT03668067)
- Testing
- 2WIN photoscreener
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- Alaska Blind Child Discovery
Encephalopathy, Birth Defect
Clinical Utility of Pediatric Whole Exome Sequencing
The investigator aims to examine the clinical utility of WES, including assessment of a variety of clinical outcomes in undiagnosed pediatric cases.
- Conditions
- Encephalopathy, Birth Defect, Intellectual Disability, Multiple Congenital Anomaly
- Trial name
- NCT03525431
- Testing
- Whole Exome Sequencing
- Where
- 4 sites in United States
- Volunteers
- 529 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder, Autism Spectrum Disorder (ASD)
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
This observational study evaluates the real-world use of intranasal insulin in children and young adults with autism spectrum disorder (ASD) utilizing the ViaNase™ device developed by Kurve Therapeutics.
- Conditions
- Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language
- Trial name
- IN-INS-AUT (NCT07521371)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Amyotrophic Lateral Sclerosis, Brain Stem Stroke
Real World Testing of a Brain-Computer Interface
The goal of this project is to test a new AAC-BCI device comparing gel and dry electrode headgear used for communication while providing clinical care.
- Conditions
- Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury
- Trial name
- NCT04026581
- Testing
- Speech generating device (SGD) evaluation including BCI access, Training and treatment
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Developmental Delay, Cerebral Palsy
Mobility Training to Improve Motor Behavior in Toddlers With or at Risk for Cerebral Palsy: A Pilot Study
Background: People who have cerebral palsy often have difficulty walking and moving their legs. Cerebral palsy is sometimes not identified until a child is almost 2 years of age, which means that early motor skill development can…
- Trial name
- NCT01253083
- Testing
- mobility training with dynamic body weight support
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Aphasia
Analysis of Brain Activity to Uncover Brain-behavior Relationships Related to Therapy Outcomes in Aphasia
Aphasia is a loss of language due to stroke or other brain injury. Word-finding in conversation is a universal and persistent difficulty in aphasia.
- Trial name
- NCT03550092
- Testing
- Abstract Semantic Association Network Training (AbSANT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Penn State University
Refractory Epilepsy, Development Delay
European Non-interventional Study on Refractory Epilepsy With Developmental Delay
This is a multinational, multicentre, non-interventional, retrospective data collection (manual Medical Chart Review).
- Trial name
- NCT04398667
- Where
- 19 sites in France, Germany and 2 more
- Volunteers
- 93 people
- Sponsor
- Zogenix, Inc.
Reading Disorder
A Multisensory Music Intervention for Children With Reading Disorders (RitMoZ)
With this study, we wish to test how effective/ beneficial music activities can be for children with dyslexia.
- Trial name
- NCT05137353
- Testing
- Music Training (RitMoZ Training), Spelling Training
- Where
- Hungary
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Research Centre for Natural Sciences
Swallowing Disorder, Perinatal Asphyxia
Effect of Non-nutritive Sucking on Transition to Oral Feeding in Infants With Asphyxia
The transition period to full oral feeding in infants with perinatal asphyxia is important in predicting long-term outcomes. The transition to independent oral feeding is accepted as a discharge criterion by the American Academy…
- Conditions
- Swallowing Disorder, Perinatal Asphyxia, Feeding; Difficult, Newborn, Feeding Disorder of Infancy or Early Childhood
- Trial name
- NCT05687708
- Testing
- Non-Nutritive Sucking
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medipol University