Clinical trials: Breast Cancer Risk Factors
Metabolic Disturbance, Sedentary Behavior
Multiple Risk Factor Intervention Trial in Breast Cancer Survivors
This study aims to produce new evidence on the efficacy of exercise and diet for cardiometabolic risk reduction in BC survivors.
- Conditions
- Metabolic Disturbance, Sedentary Behavior, Breast Cancer Female
- Trial name
- MsFITBC (NCT06454864)
- Testing
- Guidelines-based healthy eating, Guidelines-based physical activity, Stretching exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of Toronto
Colorectal Cancer, Breast Cancer
Case Control Study to Identify Modifiable Risk Factors for Colorectal and Breast Cancer in Nigeria
This project is a case-control study which seeks to identify modifiable risk factors for breast and colorectal cancer in Nigeria.
- Trial name
- NCT05044689
- Testing
- Questionnaire, Bioimpedance/Body Composition Unit
- Where
- Nigeria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital
Breast Cancer Females
Chronic Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. Despite the evidence that aromatase inhibitor therapy is associated with increased risk of cardiovascular events, potentially related to…
- Trial name
- STRIVE-Chronic (NCT06776458)
- Testing
- N/A - Usual Care
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer
Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer
RATIONALE: 1. . To compare the effects on breast cancer of three different combinations of drugs which are commonly used to treat this disease. 2. . It is not yet known which treatment regimen is most effective for breast cancer.
- Trial name
- NCT00014222
- Testing
- epoetin alfa, filgrastim, cyclophosphamide
- Where
- 78 sites in United States, Canada
- Volunteers
- 2,104 people
- Sponsor
- NCIC Clinical Trials Group
Breast Cancer
Nutrition-Related Biomarkers in Predicting Breast Cancer Risk in Women
RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about nutrition-related changes that identify biomarkers related to cancer.
- Trial name
- NCT00900367
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, spectroscopy
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Bone Metastases, Breast Cancer
Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases
Bone is the most common site of distant breast cancer recurrence, and 65-75% of women with advanced breast cancer will develop bone metastases during the course of their disease.
- Trial name
- PROVISTII (NCT01144481)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Breast Cancer, Breast Reconstruction
Implant-based Breast Reconstruction in Post-bariatric Women - a Registry-based National Study
The goal of this national registry-based study is to investigate the prevalence of reconstructive breast surgery and risk factors for surgical complications in women who have had weight loss surgery previously.
- Conditions
- Breast Cancer, Breast Reconstruction, Bariatric Surgery, Breast Implant
- Trial name
- NCT07059104
- Testing
- Breast augmentation, Breast reconstruction after mastectomy
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer
Genes and Other Risk Factors for Second Primary Breast Cancer in Women With Breast Cancer and Their Female Family Members and Friends
RATIONALE: Studying samples of blood, urine, and tumor tissue in the laboratory from patients with cancer and their female relatives and friends may help doctors learn more about changes that occur in DNA and identify biomarkers…
- Trial name
- NCT00896818
- Testing
- DNA analysis, genetic linkage analysis, loss of heterozygosity analysis
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cancer Research UK
Breast Cancer Females
Short-term Impacts of Endocrine Therapy on Cardiovascular and Brain Health Outcomes in Breast Cancer
Aromatase inhibitors are the most used endocrine therapy for hormone-positive breast cancer. While there is a clear linear relationship between the duration of aromatase inhibitor use and the cumulative incidence of…
- Trial name
- STRIVE (Acute) (NCT06781762)
- Testing
- N/A (Usual Care)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Metastatic Breast Cancer
Palbociclib Induced Neutropenia; Risk Factors and Treatment Outcome in Metastatic Breast Cancer Patients
Aim of the study to assess the neutropenia induced by Palbociclib in patient receiving Palbociclib in combination with hormonal treatment as first-line therapy in metastatic hormone receptor- positive HER2 negative breast cancer.
- Trial name
- NCT06076772
- Testing
- Palbociclib
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- Assiut University
Breast Cancer, Insulin Resistance
Alternative Physical Activity Strategies for Breast Cancer Survivors
The primary aim of this study is to compare the acute glycemic effects of two novel, alternative physical activity (PA) strategies (dispersed post-meal PA, PA snacks) to a no PA condition and to exercise sessions representing the…
- Conditions
- Breast Cancer, Insulin Resistance, Cardiometabolic Risk Factors
- Trial name
- PACE (NCT06633380)
- Testing
- Standard Physical Activity - Fasted, Standard Physical Activity - Post-Meal, Dispersed Physical Activity
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stroke, Transient Ischemic Attack
The "COSMOS"-Study (Copeptin in Osmoregulation and Stress Assessment)
Sodium imbalance is common and an adverse prognostic factor in hospitalized patients. However, identifying the causes of sodium imbalance is challenging in clinical practice.
- Trial name
- NCT00390962
- Where
- Switzerland
- Volunteers
- 469 people
- Sponsor
- University Hospital, Basel, Switzerland