Clinical trials: CAD
Hyperlipidemia, Familial Combined, Coronary Disease
Understanding the Genetic Basis of Familial Combined Hyperlipidemia in Mexican Individuals
Familial combined hyperlipidemia (FCHL) is an inherited disorder characterized by elevated levels of cholesterol and triglycerides; it often occurs in Mexican individuals with coronary heart disease (CHD).
- Trial name
- NCT00365235
- Where
- Mexico
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Coronary Artery Disease
Prognosis and Antiplatelet Strategies for Patients With PCI and High Bleeding Risk:A Study Protocol
Percutaneous coronary intervention (PCI) is an important treatment strategy for patients with coronary artery disease. Combined bleeding after PCI significantly increases the risk of death in patients.
- Trial name
- NCT05369442
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- West China Hospital
Coronary Artery Bypass Grafting, Off-pump Coronary Artery Bypass
Safety and Effectiveness of No-touch Technique for Ascending Aorta in MICS-CABG
The goal of this single-center prospective cohort study is to compare perioperative safety metrics and follow-up survival analyses in patients receiving Minimally Invasive Cardiac Surgery Coronary Artery Bypass…
- Conditions
- Coronary Artery Bypass Grafting, Off-pump Coronary Artery Bypass, Minimally Invasive Cardiac Surgery, Coronary Arterial Disease (CAD)
- Trial name
- NCT07172620
- Testing
- Non-extracorporeal multiple coronary artery bypass graft (CABG) performed under direct visualization through a small incision in the left side of the chest., Multi-branch coronary artery bypass grafting with conventional median open heart and off-pump circulation
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease
Hemodynamic Forces at Rest and Stress vs. Adenosine and Dobutamine Stress Cardiac Magnetic Resonance
Stress perfusion CMR has recently considered as one of the methods of choice for establishing the diagnosis of CAD based on its high diagnostic accuracy, lack of ionizing radiation as well as its ability to simultaneously assess…
- Trial name
- CMR (NCT04247698)
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Assiut University
Cardiovascular Diseases, Heart Diseases
Vascular Disease--Structure/Function
To investigate the relationship of non-invasively measured flow-mediated brachial artery dilation with coronary artery disease (CAD).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005506
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Lupus Cohort--Thrombotic Events and Coronary Artery Disease
To study longitudinally the incidence, pathogenesis, and risk factors for thrombotic events and coronary artery disease in a cohort of patients with systemic lupus erythematosus (SLE).
- Conditions
- Cardiovascular Diseases, Coronary Disease, Thrombosis, Heart Diseases
- Trial name
- NCT00005436
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Complete Denture
Clinical Assessment of CAD/CAM Monolithic Complete Denture
The aim of the study is to evaluate trueness, tooth position, retention, and patient satisfaction of CAD/CAM monolithic complete denture
- Trial name
- NCT07091552
- Testing
- CAD/CAM monolithic denture, Conventional denture
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Eman Assam
Cardiovascular Diseases, Cerebrovascular Accident
Low Cholesterol and Mortality in Blacks and Women
To determine and compare the long term (thirty year) relationship of total cholesterol and mortality in Blacks and whites in a predominantly urban Charleston, South Carolina cohort and a predominantly rural Evans County, Georgia…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Heart Diseases
- Trial name
- NCT00005430
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Arteriosclerosis
Multicenter Postmarket Surveillance Registry Evaluating Performance and Long Term Safety of the Presillion Stent
The purpose of this study is: To evaluate the safety and performance of the Presillion stent in routine clinical practice.
- Trial name
- NCT00968019
- Testing
- Presillion stent
- Where
- 13 sites in Portugal, Spain
- Volunteers
- 318 people
- Sponsor
- Johnson and Johnson, S.A.
Coronary Artery Disease, Heart Failure
Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes
To demonstrate that using continuous mechanical lung ventilatory support in combination with Positive End Expiratory Pressure (PEEP)during open heart surgery will improve lung function and decrease lung complications after…
- Trial name
- PEEP (NCT01522222)
- Testing
- continuous, mechanical ventilatory support
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Aurora BayCare Medical Center
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Cardiovascular Diseases, Heart Diseases
Genetic Epidemiology of Blood Lipids and Obesity - Ancillary to NGHS
To conduct a genetic epidemiologic study of the coronary heart disease (CHD) risk factors of blood lipids and obesity in Black and white girls who participated in the NHLBI-supported National Growth and Health Study (NGHS).
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Obesity
- Trial name
- NCT00005345
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Disease, Heart Diseases
VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis
To evaluate additional cardiovascular risk factors using data from the VA HDL Intervention Trial (VA-HIT).
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Carotid Artery Diseases
- Trial name
- NCT00035711
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Framingham Cycle V Offspring-Spouse Nutrition Studies
To examine the associations between diet, nutrition and coronary heart disease (CHD) incidence over seven years using the Cycle V Framingham Offspring/Spouse examination ; to examine the cross-sectional associations between…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Hypertension
- Trial name
- NCT00005347
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Significant Coronary Artery Disease
Coronary Hybrid Revascularisation Study
The purpose of the registry is to assess results of combined operative and catheter based (hybrid procedure) treatment of patients with significant coronary artery disease using essential clinical and angiographic parameters.
- Trial name
- NCT01496664
- Testing
- Combined CABG and PCI
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Disease
Using Intraoperative Coronary Bypass Graft Imaging to Improve Graft Patency
The primary objective of the proposed study is to determine if a strategy of intraoperative patency assessment and graft revision can decrease the rate of graft occlusion or significant stenosis (>50%) at 6-12 weeks after…
- Trial name
- GRIIP (NCT00187421)
- Testing
- Indocyanine green intraoperative angiogram and transit-time flowmetry
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- Sunnybrook Health Sciences Centre
Coronary Artery Disease
Ivabradine to Improve Endothelial Function in Patients With Coronary Artery Disease
This study evaluates the effect of ivabradine on endothelial function in patients with coronary artery disease (CAD) after complete revascularization with percutaneous coronary angioplasty (PCI).
- Trial name
- RIVENDEL (NCT02681978)
- Testing
- Ivabradine, Standard medical therapy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Campus Bio-Medico University
Cardiovascular Diseases, Coronary Disease
Coronary Calcification Progression Study
To investigate use of Fast Gated Helical Computed Tomography (FGHCT) measures of coronary artery calcium (CAC), FGHCT-CAC, for discrimination of coronary artery disease (CAD) and to quantify progression of coronary artery calcium…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00006526
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Registry to Evaluate Efficacy of Xience/Promus Versus Cypher in Reducing Late Loss After Stenting
The objective of this study is to evaluate the safety and long-term effectiveness of coronary stenting with the everolimus-eluting stent (EES) and to determine clinical device and procedural success during commercial use of EES…
- Trial name
- NCT00960648
- Testing
- Xience/Promus, Cypher
- Where
- 18 sites in South Korea
- Volunteers
- 3,056 people
- Sponsor
- Seoul National University Hospital
Aortic Valve Sclerosis
Relation Between Aortic Sclerosis &Severity of Coronary Heart Disease.
the goal of the study to identify the relation between aortic valve sclerosis and severity of coronary heart disease by performing transthoracic echo Doppler study for severity of aortic valve sclerosis in patient will undergo…
- Trial name
- NCT06965218
- Testing
- Trans thoracic echo doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University