Clinical trials: CAD-CAM
Mouthguard Use, Orofacial Injuries Prevention
Impact of 3D-Printed and Custom Mouthguards on Speech and Oral Functions in Children Practicing Contact Sports
This study aims to compare the effects of traditional and 3D-printed custom-made mouthguards on speech and oral functions in pediatric cases who practice contact sports by evaluating the comfort, fit, and performance of both…
- Conditions
- Mouthguard Use, Orofacial Injuries Prevention, 3D Printed Mouthguard, Traditional Custom-made Mouthguard
- Trial name
- Mouthguards (NCT06972823)
- Testing
- 3D printed custom-made mouthguards, Traditional custom-made mouthguards
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Relapse
CAD/CAM Fixed Retainers vs. Conventional Multistranded Fixed Retainers in Orthodontic Patients. Comparison of Stability, Retainer Failure Rate, Adverse Effects, Cost-effectiveness, and Patient Satisfaction. A Randomized Controlled Clinical Trial
Introduction: Orthodontic retainers are used after the completion of orthodontic treatment to assure dental occlusal stability and to maintain the achieved end-result.
- Trial name
- Retention (NCT04389879)
- Testing
- Bonding of either CAD/CAM or conventional multistranded stainless steel fixed retainer
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Mouthguard Use Orofacial Injuries Prevention 3D Printed Mouthguard Traditional Custom-made Mouthguard Occlusal Thickness Changes
Comparative Assessment of Thickness Changes in 3D-Printed vs. Custom-Made Mouth Guards for Children in Contact Sports
This study aims to compare changes in the thickness of traditional and 3D-printed custom mouth guards in pediatric athletes who participate in contact sports.
- Trial name
- NCT07000435
- Testing
- 3D printed custom-made mouth guards, Traditional custom-made mouth guards
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Speech, Denture, Partial, Removable
Intelligibility and Acoustic Speech Performance of CAD/CAM Milled Titanium Partial Dentures
Partial dentures play a crucial role in restoring oral function and aesthetics for patients with missing teeth. Traditionally, these prostheses have been fabricated using materials such as acrylic resin or cobalt-chromium alloys.
- Conditions
- Speech, Denture, Partial, Removable, CAD-CAM
- Trial name
- NCT06589570
- Testing
- Removable Partial Denture
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Occlusion, Prosthesis Durability
Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III Cases
This study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health…
- Trial name
- NCT07215208
- Testing
- CAD/CAM metallic partial denture frameworks, Conventional metallic partial denture frameworks
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH
This study will be performed to evaluate the clinical performance (Plaque accumulation, fracture of (restoration or tooth), postoperative sensitivity, secondary caries, marginal fit and discoloration) of two CAD/CAM fabricated…
- Trial name
- NCT05434884
- Testing
- occlusal veneer restorations, endocrown restorations
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Patient Satisfaction
Patient Centered Outcomes and Marginal Bone Changes in CAD/CAM Metallic and (PEEK) Partial Denture Frameworks
To compare PEEK to metallic partial denture frameworks in restoring mandibular Kennedy class I regarding patient satisfaction.
- Trial name
- NCT05622448
- Testing
- RPD with PEEK framework, RPD with metallic framework
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss, Dental Implant
A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort Study
The goal of this prospective cohort study is to evaluate the clinical performance of a new generation of customized CAD/CAM pre-fabricated root-analog dental implants over a 36-month period.
- Trial name
- NCT06576284
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Edentulous, Jaw
Passive Fit of CAD/CAM Screw-retained Metal Frameworks Versus Screwmented Ones
CAD/CAM (computer aided design/ computer aided manufacturing) constructed screw retained implant supported frameworks give solutions for the problems arising from the lost wax technique by improving accuracy, adaptation and…
- Trial name
- NCT04372901
- Testing
- Digitally constructed frameworks before implant placement, Digitally constructed frameworks after implant placement
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lefort I Osteotomy
Waferless One Stage Segmental Lefort I Maxillary Positioning in Transverse Deficiency
In Maxillary transverse deficiency, is waverless lefort I multiple pieces osteotomy using virtually planned patient specific titanium implants feasible and does it provide accuracy? This prospective case series study evaluating…
- Trial name
- NCT03884699
- Testing
- Accuracy of planned transverse Maxillary distance using Mimics software after fixation using Patient specific implant
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Denture, Complete, Jaw, Edentulous
Milled Versus Printed CAD/CAM Complete Dentures
A crossover clinical trial investigates two novel CAD/CAM techniques for complete removable dental prostheses for edentulous patients, milling and rapid prototyping (3D-printing) in a clinical setting of an undergraduate student…
- Trial name
- MILLPRINT (NCT04873219)
- Testing
- manufacturing a complete dental prosthesis
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Endodontic Treatment, Tooth Restoration
Endodontic Posts Using the CAD/CAM Digital Method.
This study investigates the survival and success rates of endodontic posts exclusively fabricated using the CAD/CAM digital method over a period of 5 years of intraoral use.
- Trial name
- NCT07297108
- Testing
- Lithium Disilicate CAD/CAM Post, Active Comparator: Polymer-Based CAD/CAM Posts
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Tooth Wear
Survival and Success of CAD/CAM Restorations After 5 Years of Intraoral Use
This study evaluates the survival and success rates of dental restorations fabricated exclusively using CAD/CAM technology over a period of 5 years.
- Trial name
- NCT07276269
- Testing
- CAD/CAM Digital Restoration Placement, Study of the Survival and Success of Endodontic Posts Using the CAD/CAM Digital Method After 5 Years of Intraoral Use
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Edentulous Jaw
Intraoral Scanning v.s Desktop Scanning
The aim of this study was to evaluate the effect of intraoral scanning versus desktop scanning on the retention and adaptation of maxillary denture bases in completely edentulous patients.
- Trial name
- NCT06509269
- Testing
- intraoral scanning, Desktop scanning
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Resin Cement
Evaluation of Marginal Integrity Using Bioactive Cement Incementation of Indirect Composite Blocks
The aim of this study is to evaluate of marginal integrity of indirect composite restoration after cementation by a bioactive cement in comparison to dual cure resin cement using Modified USPHS criteria
- Trial name
- NCT04557657
- Testing
- Active bio Activa, Resin Cement
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Hypomineralization, Incisor
Comparison of the Long-Term Success of Different CAD-CAM Blocks Used as Indirect Restorations in Molar Incisor Hypomineralized Teeth: A Split Mouth Study
This study is about the long-term survival success of different, externally prepared fillings (Indirect restoration, CAD-CAM blocks) used in teeth with reduced mineral structure, namely Molar Incisor Hypomineralization (MIH)…
- Trial name
- NCT07144605
- Testing
- CAD-CAM, indirect restorations
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Palatal Expansion Technique
Evaluation of Hard and Soft Tissue Change During Maxillary Expansion Using a Computer-aided Design / Computer-aided Manufacturing Appliance.
Hard tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance. Soft tissue changes during the transversal expansion of the maxilla using a CAD/CAM expansion appliance.
- Trial name
- NCT06246656
- Testing
- Maxillary Expansion
- Where
- Austria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Orthodontic Appliances, Fixed
Computer-aided Indirect Bonding Versus Traditional Direct Bonding of Brackets in Orthodontic Patients
Accurate bracket positioning is one of the keys for effective orthodontic treatment. Traditionally, orthodontic brackets are positioned one-by-one on the teeth of the patient, with the so-called direct bonding method.
- Trial name
- NCT04395625
- Testing
- Direct bonding of Orthodontic brackets, Indirect bonding of Orthodontic brackets
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Restoration of Primary Molars With CAD/CAM Crowns
Primary Molars Restoration Using Different Pediatric Crowns.
study aims to compare hybrid ceramic CAD/CAM and prefabricated zirconia ans stainless steel crowns restoring primary molars through In-vivo evaluation of the clinical outcomes in terms of; crown retention, stain resistance and…
- Trial name
- NCT04144062
- Testing
- CAD/CAM crowns
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nehal Salman