Clinical trials: COPD Chronic Obstructive Pulmonary Disease
Pulmonary Disease, Chronic Obstructive
Pharmacovigilance Study to Evaluate Safety of SERETIDE in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Primary objective: Evaluation of the safety of Seretide discus administration in subjects with COPD. Treatment duration: 2 years. Study has 3 phases: Screening phase (visit 1), treatment phase (visits 2-5.
- Trial name
- NCT00662805
- Testing
- Salmeterol/Fluticasone propionate
- Volunteers
- 762 people
- Sponsor
- GlaxoSmithKline
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Chronic Obstructive Airway Disease
Continuous Versus Interval Walking Training in Patients With COPD - a Pilot Study
This study will investigate the effects of interval walking training versus continuous walking training in patients with chronic obstructive pulmonary disease.
- Trial name
- NCT02209207
- Testing
- Treadmill, walking training
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Pulmonary Disease
Physical Activity Counseling During Pulmonary Rehabilitation
This randomized controlled trial will assess the effect of adding intensive physical activity counseling to an outpatient pulmonary rehabilitation program.
- Trial name
- PAC (NCT00948623)
- Testing
- physical activity counseling program
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- KU Leuven
Chronic Respiratory Disease, Asthma
Remote Monitoring of Respiratory Health
Recently, interest in ways to monitor and care for patients remotely has significantly increased due to concerns for infection control as well as a way to increase access to regular clinic visits that may be limited for…
- Conditions
- Chronic Respiratory Disease, Asthma, Copd
- Trial name
- NCT04739943
- Testing
- Mobile Monitoring
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pulmonary Disease, Chronic Obstructive
Pharmacokinetic Study in Elderly Patients With Chronic Obstructive Bronchitis (COPD)
Study to evaluate the pharmacokinetics of tiotropium following 14 days of administration (18µg once per day) in elderly COPD patients.
- Trial name
- NCT02172326
- Testing
- Tiotropium inhalation capsules for oral inhalation
- Volunteers
- 29 people
- Sponsor
- Boehringer Ingelheim
COPD, Copd Bronchitis
Muco-ciliary Cleansing of Lungs in COPD With and Without a Salt Particle Inhaler
Cross-over trial of the effect of a salt particle inhaler on pulmonary muco-ciliary cleansing in COPD patients as measured by lung scintigraphy.
- Trial name
- NCT03927365
- Testing
- Inhalation from a salt particle inhaler with or without content
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Liita Care ApS
COPD
Dyspnea Threshold During 6 Minutes Walk Test
In view of the multiple limitations and restrictions relative to CPET (technical, time, physical…), determination of individualized training threshold from this evaluation is today not possible for a lot of patients.
- Trial name
- SD6 (NCT02082925)
- Testing
- Patient has to get up his hand when he defined his dyspnea threshold during 6MWT
- Where
- France
- Volunteers
- 82 people
- Sponsor
- 5 Santé
Chronic Obstructive Pulmonary Disease
Telehealth Monitoring in Chronic Obstructive Pulmonary Disease
The the aim of this study is to determine the benefits of Telehealth monitoring in the management of patients with chronic obstructive pulmonary disease.
- Trial name
- NCT01522859
- Testing
- Telehealth monitoring system (Honni Med)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- South Eastern Health and Social Care Trust
COPD, Non Invasive Ventilation
Prospective Cohort of Respiratory Insufficiency Outcome
The Respiratory Insufficiency Outcome (RIO) project consists in a french multicenter prospective cohort of patients with chronic obstructive pulmonary disease (COPD) undergoing domiciliary noninvasive positive pressure…
- Trial name
- RIO (NCT01192451)
- Where
- 4 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Chronic Obstructive Pulmonary Disease
Evaluation of Consumption of Sevoflurane in Chronic Obstructive Pulmonary Disease Patients
All the Patients undergoing General Anesthesia and the patients who are having Chronic Obstructive Pulmonary Disease will be considered for this study.
- Trial name
- SevoCOPD (NCT06108973)
- Testing
- Capnography
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Employee's State Insurance Corporation, New Delhi
Lung Cancer, Precancerous Condition
Screening for Lung Cancer in Current or Past Smokers With Chronic Obstructive Pulmonary Disease
RATIONALE: Screening tests or exams may help doctors find lung cancer sooner, when it may be easier to treat. PURPOSE: This randomized clinical trial is studying screening tests or exams to see how well they work compared to…
- Trial name
- NCT00512746
- Testing
- cytology and cytometry specimen collection procedure, Chest x ray, Autofluorescence bronchoscopy
- Where
- 10 sites in United Kingdom
- Volunteers
- 1,569 people
- Sponsor
- University College, London
Chronic Obstructive Pulmonary Disease, COPD
The Effect of Breathing Helium-Hyperoxia During Pulmonary Rehabilitation in Patients With COPD
The purpose of this study is to examine whether breathing helium-hyperoxia during exercise in a pulmonary rehabilitation program can improve the exercise tolerance and health related quality of life of patients with Chronic…
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Emphysema, Lung Diseases
- Trial name
- NCT00406705
- Testing
- Helium-Hyperoxia
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Paediatric Asthma
Design, Development and Evaluation of a Digital Health Assistant for Paediatric Asthma
This study is to evaluate the efficacy of the digital health assistant (DHA) "Alex" in improving asthma control in asthmatic children and adolescents aged 10 to 19 compared to their baseline values.
- Trial name
- ALEX (NCT07472283)
- Testing
- Phase I (months 1-3): DHA core functionality, Phase II (months 3-6): platform augmentation, Embedded qualitative study
- Where
- 5 sites in Romania
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital Basel
Respiratory Tract Diseases
Evaluation and Reconditioning of Marginal Lung Donors to Transplantation by ex Vivo Lung Perfusion
Only about 15% of the potential candidates for lung donation are considered suitable for transplantation. A new method for ex vivo lung perfusion (EVLP) has been developed and can be used for evaluation and reconditioning of…
- Trial name
- NCT01353105
- Testing
- Ex vivo lung transplantation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- InCor Heart Institute
Pulmonary Disease, Chronic Obstructive
Special Drug Use Investigation for ADOAIR DISKUS COPD (Salmeterol and Fluticasone)
To investigate possible problems or questions in safety and effectiveness of salmeterol and fluticasone in patients with chronic obstructive pulmonary disease (bronchitis chronic / emphysema).
- Trial name
- NCT01332409
- Testing
- Salmeterol and Fluticasone
- Where
- Japan
- Volunteers
- 2,000 people
- Sponsor
- GlaxoSmithKline
Chronic Obstructive Pulmonary Disease
Vitamin D as Treatment for Chronic Obstructive Pulmonary Disease (COPD)
This project aims to explore the relationship between Vitamin D deficiency and COPD progression via a prospective randomized placebo-controlled study.
- Trial name
- NCT00666367
- Testing
- D-cure
- Where
- 2 sites in Belgium
- Volunteers
- 182 people
- Sponsor
- KU Leuven
Chronic Obstructive Pulmonary Disease
Effects of an Inpatient Rehabilitation for Patients With Chronic Obstructive Pulmonary Disease (COPD) III/IV
The purpose of this study is to determine if there is a change in the CAT-score after an inpatient rehabilitation of three weeks and if it correlates with other common parameters.
- Trial name
- NCT01418768
- Testing
- inpatient rehabiliation
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Emphysema or COPD
Chartis Collateral Ventilation Measurement: Conscious Sedation Versus General Anesthesia
Rationale: The Chartis® ( Pulmonx, CA, USA) measurement system is a tool to assess interlobar collateral ventilation during bronchoscopy.
- Trial name
- NCT03205826
- Testing
- Type of sedation used
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen