Clinical trials: COPD Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
This is an open-label Phase II study assessing the PD of dexpramipexole 150 mg twice daily (BID) in participants with eosinophilic COPD.
- Trial name
- SUSPIRE-1 (NCT06533553)
- Testing
- Dexpramipexole Dihydrochloride
- Where
- 23 sites in United States
- Volunteers
- 30 people
- Sponsor
- Areteia Therapeutics
COPD
Prospective Dynamic Cohort Study of Phenotypic Profiles in Patients With Chronic Obstructive Pulmonary Disease
This prospective, multicenter, real-world observational cohort study will describe phenotypic profiles, patient characteristics, and treatments in adults with stable chronic obstructive pulmonary disease (COPD).
- Trial name
- COPD-BPCO 2 (NCT07627763)
- Testing
- Routine care / no study-specific intervention
- Where
- 7 sites in France
- Volunteers
- 500 people
- Sponsor
- Initiatives Bronchopneumopathie Chronique Obstructive (BPCO)
Pulmonary Disease, Chronic Obstructive, Smoking
Electronic Proactive Outreach for Smokers With COPD
Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases, with 90% of cases directly attributable to smoking. Unfortunately, many patients continue to smoke and have an urgent need to quit.
- Trial name
- NCT04462289
- Testing
- Proactive Outreach
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- VA Office of Research and Development
Protein; Disease
Pilot Study on Proteomics of Erythrocyte Proteins in Patients With COPD Based on TMT Technology
Chronic obstructive pulmonary disease (COPD), a common and complex disease characterized by persistent airflow limitation, is a leading cause of mortality worldwide. COPD and its comorbidity are associated with hypoxia condition.
- Trial name
- NCT05376618
- Testing
- no intervention
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Cancer, Heart Failure
Improving Pharmacological Transition of Palliative Care Patients From Inpatient to Outpatient Care
The transition of palliative care patients from inpatient to outpatient care is aimed to be improved through structured pharmaceutical discharge management by a trained pharmacist.
- Conditions
- Cancer, Heart Failure, COPD
- Trial name
- EntMedPall (NCT06648733)
- Testing
- Structured pharmaceutical discharge management
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Muenster
Chronic Obstructive Pulmonary Disease
Effects of IPV Assessed With Functional Imaging
In this study the invetigators seek an answer on the following hypothesis: What are the long term effects of an IPV treatment evaluated with classical outcome parameters? (FEV1, Raw) Is the possible effect noticeable on the novel…
- Trial name
- IPV (NCT01671540)
- Testing
- intrapulmonary percussive ventilation, standard treatment
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
COPD, Interstitial Lung Disease
Effects of an Oxymizer on Endurance Time in Patients With Chronic Lung Diseases
The Oxymizer pendant® is a special oxygen cannula that can be used to supply high flow long term oxygen therapy. It is compatible with a wide variety of oxygen sources.
- Trial name
- NCT01713413
- Testing
- Oxymizer, conventional nasal cannula
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Chronic Obstructive Pulmonary Disease
Infectious Etiology of Acute Exacerbations of COPD
To assess the infectious etiology related to acute exacerbation of COPD in Hong Kong
- Trial name
- NCT00441389
- Volunteers
- 500 people
- Sponsor
- Chinese University of Hong Kong
COPD, Physical Activity
Intervention Study to Investigate Supplemental Oxygen in COPD
The purpose of this trial is to study the effects on exercise capacity, physical activity, inflammatory markers and quality of life of supplemental ambulatory oxygen, to be used during physical activity, in patients with COPD who…
- Conditions
- COPD, Physical Activity, Sedentary
- Trial name
- NCT01783808
- Testing
- Supplemental oxygen
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- Uppsala University
Pulmonary Disease, Chronic Obstructive
Pharmacokinetic Study in Elderly Patients With Chronic Obstructive Bronchitis (COPD)
Study to evaluate the pharmacokinetics of tiotropium following 14 days of administration (18µg once per day) in elderly COPD patients.
- Trial name
- NCT02172326
- Testing
- Tiotropium inhalation capsules for oral inhalation
- Volunteers
- 29 people
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
Effect of Intravenous Iron (Ferinject®) on Exercise Capacity and Quality of Life of Stable COPD Patients
Disordered iron metabolism characterizes an important determinant of impaired exercise tolerance and work capacity. Iron-deficiency anemia commonly features impaired aerobic capacity caused by decreased oxygen carrying capacity…
- Trial name
- NCT02416778
- Testing
- Ferric carboxymaltose, Ferinject® 50mg Iron/ml Solution for Injection / Infusion
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Georg-Christian Funk
Chronic Obstructive Pulmonary Disease
Effects on PaCO2 Levels of Two Different Nasal Cannula in COPD Patients
High-flow nasal cannula (HFNC) therapy is increasingly used in the management of acute respiratory failure. Its clinical application has been expanded also in other specific settings In stable COPD patients and in those…
- Trial name
- CODUET (NCT05528289)
- Testing
- AIRVO 2, with conventional symmetric nasal cannula, AIRVO 2, the new asymmetric nasal cannula
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Obstructive Pulmonary Disease
Human Immunodeficiency Virus (HIV)and Chronic Obstructive Pulmonary Disease (COPD)
Highly active antiretroviral therapy (HAART) has considerably improved survival of HIV-infected patients. Opportunist diseases and cancers linked to immunodepression have largely regressed.
- Trial name
- HIV and COPD (NCT01639274)
- Testing
- COPD prevalence
- Where
- France
- Volunteers
- 639 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Diabetes, Cholesterol
Interprofessional Pharmacogenomics (IPGx) Registry and Repository
This program collects genetic and health information to help doctors choose the right medications for patients.
- Conditions
- Diabetes, Cholesterol, Cancer, Blood Pressure Disorders
- Trial name
- IPGx Registry (NCT06726590)
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Texas A&M University
Chronic Obstructive Pulmonary Disease (COPD)
Evaluation of the Effect of PUR118 on Ozone Induced Airway Inflammation in Healthy Normal Volunteers
This trial in healthy subjects will assess PUR118's effect on attenuating ozone induced airway inflammation. This trial will establish the tolerability of PUR118 in healthy normal volunteers.
- Trial name
- NCT01690949
- Testing
- PUR118
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pulmatrix Inc.
Chronic Obstructive Pulmonary Disease (COPD)
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations
The purpose of this Phase III study is to evaluate the efficacy and safety of tozorakimab Dose 1 and Dose 2 administered subcutaneously (SC) in adult participants with symptomatic COPD and history of ≥ 2 moderate or ≥ 1 severe…
- Trial name
- OBERON (NCT05166889)
- Testing
- Tozorakimab
- Where
- 212 sites in United States, Argentina and 19 more
- Volunteers
- 1,132 people
- Sponsor
- AstraZeneca
COPD,Pulmonary Disease, Chronic Obstructive ,Pulmonary Disease, Chronic Obstructive
Effect of Introducing Digital Multimedia Nursing on Improving With COPD
COPD is a progressive and irreversible lung disease characterized by persistent airflow limitation, dyspnea, chronic cough, and impaired daily functioning, often accompanied by comorbidities that reduce quality of life.
- Trial name
- COPD (NCT07419906)
- Testing
- E-book on Pulmonary Obstruction
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Fu Jen Catholic University Hospital
Chronic Obstructive Pulmonary Disease
The Short Physical Performance Battery in Chronic Obstructive Pulmonary Disease (COPD)
Patients with COPD often have limitations to physical performance. There are several tests for evaluating physical performance, unfortunately many of them can be time consuming and require specialized equipment an substantial…
- Trial name
- NCT02314338
- Testing
- Pulmonary rehabilitation
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- LHL Helse
Chronic Obstructive Pulmonary Disease (COPD)
Temple Health Chest Initiative (THCI 2.0)
Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to significant costs on healthcare…
- Trial name
- NCT06933758
- Testing
- Determine COPD prevalence utilizing spirometry along with CT scans and symptom assessments in the THCI lung cancer screening populatio
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Temple University
Emphysema or COPD
Improve Muscle Weakness in Patient With COPD
This randomized controlled trial investigated the effects of combining aerobic exercise with blood flow restriction (BFR) training in patients with emphysematous chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT07649850
- Testing
- Aerobic Exercise Combined with Blood Flow Restriction, Aerobic exercise
- Sponsor
- Al-Zaytoonah University of Jordan
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