Clinical trials: CORE
Spondylarthritis, Spondylarthropathies
Core Stabilization Training in Juvenile Spondyloarthropathy
Core stabilization exercises developed by McGill have been shown to be one of the physiotherapy techniques aimed at reducing pain, increasing aerobic capacity, enhancing muscle strength, and thereby improving bone health in…
- Conditions
- Spondylarthritis, Spondylarthropathies, Juvenile Idiopathic Arthritis
- Trial name
- NCT06546293
- Testing
- core stabilization exercises, daily physical activity program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Idiopathic Adolescent Scoliosis, Scoliosis Idiopathic
Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic…
- Trial name
- CSE RAB IS (NCT07601893)
- Testing
- Core Stabilization Exercises, Standard Care (in control arm)
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Antibiotic Side Effect, Behavioral Changes
Improving Antibiotic Use in Urgent Care Facilities
This study will implement a comprehensive outpatient stewardship program targeting a large network of Urgent Care (UC) clinics within Intermountain Helathcare.
- Trial name
- SCORE_UC (NCT03932708)
- Testing
- CDC Core Elements of Outpatient Stewardship
- Where
- United States
- Volunteers
- 700,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Preterm Birth
PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol]
PLATIPUS is an adaptive platform trial aimed at improving the health of infants born preterm (before 37 weeks' gestation). PLATIPUS will compare how different treatments and care provided to pregnant women and people at risk of…
- Trial name
- PLATIPUS (NCT06461429)
- Testing
- Erythromycin, Amoxicillin and Erythromycin, Azithromycin
- Volunteers
- 100,000 people
- Sponsor
- University of Melbourne
Scoliosis Idiopathic Adolescent
BSPTS and Core Stabilization Exercises in Adolescents With Idiopathic Scoliosis
This study aims to investigate the short-term effects of adding core stabilization exercises to Barcelona Scoliosis Physical Therapy School (BSPTS) exercises in adolescents with idiopathic scoliosis.
- Trial name
- NCT07761260
- Testing
- BSPTS Plus Core Stabilization Exercise, BSPTS Exercise
- Volunteers
- 36 people
- Sponsor
- Istinye University
Scoliosis Idiopathic Adolescent, Body Image
Body Awareness in Adolescent Idiopatic Scoliosis
Scoliosis is a three-dimensional deformity of the spine, and Adolescent Idiopathic Scoliosis (AIS) is the most common subtype of scoliosis.
- Trial name
- NCT06118814
- Testing
- Body Awareness Therapy Exercise, Virtual Reality Exercise, Core Stability Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hitit University
Neuromuscular Disease, Malignant Hyperthermia
The Prevalence of RYR1-related Disease
The skeletal muscle ryanodine receptor (RYR1) gene encodes an important calcium channel in skeletal muscle, with an important role in muscle contraction. Mutations (i.e.
- Conditions
- Neuromuscular Disease, Malignant Hyperthermia, Congenital Myopathy, Multiminicore Disease
- Trial name
- NCT06791369
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- King's College London
Autistic Disorder
Treating Oxidative Stress in Children With Autism
An open label trial was undertaken in 40 autistic children to determine whether treatment with metabolic precursors methylcobalamin and folinic acid would improve plasma biomarkers of oxidative stress and measures of core…
- Trial name
- NCT00692315
- Testing
- Methylcobalamin (methylB12)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Image-guided Biopsy, Complications
Renal Parenchymal Core Needle Biopsy
Percutaneous image-guided parenchymal renal biopsy has been used to detect the different pathologies of renal parenchyma, to define the degree of reversible changes, and to define when the medical treatment fails.
- Conditions
- Image-guided Biopsy, Complications, Kidney Glomerulus
- Trial name
- NCT02758535
- Testing
- coaxial renal biopsy, noncoaxial renal biopsy
- Where
- Iran
- Volunteers
- 166 people
- Sponsor
- Modarres Hospital
Diplegic Cerebral Palsy, Diaplegia
Core Stabilization and Kinesthetic Training in Diplegic CP
This randomized controlled trial aimed to compare the effects of core stabilization exercises (CSE) and kinesthetic training (KT) on postural control in children with spastic diplegic cerebral palsy (GMFCS Level III), aged 4-8…
- Trial name
- NCT07568808
- Testing
- Core Stabilization Exercises, Kinesthetic Training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- University of Lahore
Childhood Obesity
Mountain West Prevention Research Center Core Research Project
This hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial will assess the impact of integrating population health management (PHM) strategies-text messaging and enrollment in Building Healthy…
- Trial name
- MW-PRCCRP (NCT07479498)
- Testing
- Text Message-based recruitment, Active outreach follow-up
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Paul Estabrooks
Scoliosis Idiopathic Adolescent
Effect of a 16-Week Physiotherapeutic Corrective Exercise Program on Spinal Deformities in Adolescent Idiopathic Scoliosis
Brief Summary Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that may progress during adolescence and lead to postural asymmetry, spinal rotation, pelvic imbalance, reduced spinal mobility, and…
- Trial name
- SPINE-AIS16 (NCT07736456)
- Testing
- Structured Physiotherapeutic Corrective Exercise Program, Standard Physiotherapy Exercise Program
- Where
- Kosovo
- Volunteers
- 68 people
- Sponsor
- Alma Mater Europaea - Slovenia
Sports Physical Therapy
Effects of Pilates and Burpees Exercises in Core Strengthening and Dynamic Balance.
This study will be a randomized clinical trial will be conducted in Ayub national park cricket club Sample size will be 48 to evaluate the effects of Pilates and Burpees exercises training among cricket players with an age range…
- Trial name
- NCT06196970
- Testing
- Pilate exercises, Burpees exercises
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Landing Biomechanics, Jumping Performance
Effectiveness of Core Training on the Biomechanics of Jump Landing in Amateur Female Basketball Players
The goal of this clinical trial is to evaluate the effectiveness of a core training intervention on jump-landing biomechanics in female amateur basketball players.
- Conditions
- Landing Biomechanics, Jumping Performance, Trunk Stability
- Trial name
- NCT06633237
- Testing
- Core training program in female amateur basketball players
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Attention Deficit Disorder
Neurofeedback and Working Memory Training for Children and Adolescents With ADHD
The purpose of this study is to investigate if neurofeedback and working memory training improves core symptoms of ADHD in children and adolescents.
- Trial name
- KITE (NCT01841151)
- Testing
- SCP training, Live Z-score training, WM training
- Where
- Sweden
- Volunteers
- 202 people
- Sponsor
- Karolinska Institutet
Oral Disease, Bacterial Disease
El Paso Public Health Biorepository
The prevalence of tooth decay and other oral diseases are overlooked indicators of overall public health. To improve the understanding of oral health in El Paso, the City of El Paso Health Department will work with Texas Tech…
- Trial name
- EPB (NCT03123705)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Autism Spectrum Disorder
Evaluation of Theta Burst Transcranial Magnetic Stimulation in Children With Autism Spectrum Disorder
The goal of this clinical trial is to evaluate Theta Burst Transcranial Magnetic Stimulation as an adjunct to standard therapy in improving core function deficits in children 5-15 year age with Autism Spectrum disorder.
- Trial name
- NCT06040775
- Testing
- Theta Burst Transcranial magnetic Stimulation using real MCF-B65 coil
- Volunteers
- 82 people
- Sponsor
- All India Institute of Medical Sciences
AML, Childhood, Relapse/Recurrence
Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation
The purpose of this study is to evaluate the efficacy and safety of avapritinib in relapsed or refractory pediatric core binding factor acute myeloid leukemia with KIT mutation.
- Conditions
- AML, Childhood, Relapse/Recurrence, Refractory AML, Core Binding Factor Acute Myeloid Leukemia
- Trial name
- NCT06316960
- Testing
- Avapritinib, Azacitidine Injection, Decitabine Injection
- Where
- 12 sites in China
- Volunteers
- 50 people
- Sponsor
- Children's Hospital of Soochow University
Down Syndrome
Weight Bearing Exercises With and Without Jaffrey's Core Stability Exercise Training in Children With Down Syndrome.
Down syndrome also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21.
- Trial name
- NCT05719662
- Testing
- Weight bearing exercises, Jaffrey's core stability exercises
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Sports Physical Therapy
Investigation of the Relationship Between Core Endurance and Awareness of Injury Prevention in Adolescent Basketball Players
Injuries occurring during adolescence can lead to serious long-term problems. Such injuries can cause athletes to take breaks from their sports and physically strain themselves.
- Trial name
- NCT06475833
- Testing
- Prone plank test, Side plank test, The Awareness of Sports Injuries Scales
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University