Clinical trials: Calculi, Urinary, open to volunteers
Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy
Supine vs. Prone Mini-PCNL in Children
Percutaneous nephrolithotomy (PCNL) is an established intervention for large or ESWL-resistant renal stones in pediatric populations.
- Conditions
- Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy, Prone Mini Percutaneous Nephrolithotomy
- Trial name
- SUPRO-PED (NCT07887945)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Urinary Stone
Two Types of Single-use Flexible Ureteroscopies for the Treatment of Upper Urinary Tract Stones in Children
The single-use digital flexible Ureteroscopy (fURS) is commonly used for the treatment of upper urinary tract stones. The size of the outer diameter of the fURS can affect the safety, efficacy, and medical costs of the treatment.
- Trial name
- NCT06628765
- Testing
- 8.6 Fr single-use fURS (XFGC-FU-660RC), 6.3 Fr single-use fURS (Hugemed, HU30S)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Stone, Kidney
Evaluation of Retrograde Intra Renal Surgery in the T-tilted Position
To evaluate the effect of the T-tilted position on the stone-free rate compared to the standard lithotomy position in retrograde intrarenal surgeries.
- Trial name
- RIRS (NCT06860113)
- Testing
- T-tilting of the patient during surgery, standard lithotomy position
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pediatric Urolithiasis, Distal Ureteral Stone
Intravesical Aminophylline to Facilitate Ureteroscopic Access in Children With Distal Ureteral Stones.
This study will evaluate whether intravesical aminophylline can facilitate semi-rigid ureteroscopic access in children with distal ureteral stones when the first gentle attempt to enter the ureter is unsuccessful.
- Conditions
- Pediatric Urolithiasis, Distal Ureteral Stone, Ureteral Calculi
- Trial name
- NCT07617896
- Testing
- Aminophylline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Primary Hyperoxaluria Type 1, PH1
Phase I Exploratory Study of YOLT-203 in Patients With Primary Hyperoxaluria Type 1 (PH1)
This is a single-arm, open-label, single-dose dose-escalation study. It aims to evaluate the safety and tolerability of YOLT-203 in Chinese patients with Primary Hyperoxaluria Type 1 (PH1), and to preliminarily assess the effect…
- Trial name
- NCT07776626
- Testing
- YOLT-203
- Where
- China
- Volunteers
- 9 people
- Sponsor
- YolTech Therapeutics Co., Ltd
Pediatric Bladder Stones, Bladder Calculi
Vacuum-Assisted Mini-Percutaneous Versus Transurethral Cystolithotripsy in Pediatric Bladder Stones
This prospective randomized pilot study will compare vacuum-assisted mini-percutaneous cystolithotripsy with standard transurethral cystolithotripsy for the treatment of bladder stones in children.
- Conditions
- Pediatric Bladder Stones, Bladder Calculi, Pediatric Urolithiasis
- Trial name
- VAMPCL-Ped (NCT07614880)
- Testing
- Vacuum-Assisted Mini-Percutaneous Cystolithotripsy, Transurethral Cystolithotripsy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
Kidney Calculi
Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery
This prospective observational study aims to evaluate the association between anesthesia type and surgeon-perceived workload and surgical ergonomics in adult patients undergoing flexible ureteroscopy and retrograde intrarenal…
- Trial name
- RIRS-ERG (NCT07763600)
- Testing
- General Anesthesia (GA), Spinal Anesthesia (SA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Malatya Governor Research Hospital
Renal Calculi
Energy Ramping Versus Fixed Dose ESWL
This clinical trial compares two techniques of extracorporeal shock wave lithotripsy (ESWL) - energy ramping versus fixed dose - in adult patients with renal stones.
- Trial name
- NCT07334236
- Testing
- Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- mohammed Abdelhafez
Stones, Kidney, Ureter Stones
A Comparative Study Between the Usage of Flexible and Navigable Suction Ureteral Access Sheath Versus Traditional Access Sheath in Retrograde Intrarenal Surgeries
A comparative study between the Usage of Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus Traditional Access sheath in RIRS : Randomized controlled trial .
- Trial name
- NCT07076589
- Testing
- FURS
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Yosseif elhousseiny ammar ahmed
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Urinary Lithiasis
Stone Disease of the Urinary Tract in Children
The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management.
- Trial name
- Ped-Urolithia (NCT06032364)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Strasbourg, France
Bladder Calculi, Pediatric Bladder Stones
Dusting vs Fragmentation Laser Cystolithotripsy for Pediatric Bladder Stones
Bladder stones are a clinically relevant pediatric urological condition that may require endoscopic treatment. Transurethral Holmium:YAG laser cystolithotripsy is a minimally invasive option for selected children with bladder…
- Conditions
- Bladder Calculi, Pediatric Bladder Stones, Pediatric Urolithiasis
- Trial name
- DUST-FRAG-PED (NCT07623980)
- Testing
- Dusting Holmium:YAG Laser Cystolithotripsy, Fragmentation Holmium:YAG Laser Cystolithotripsy
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Primary Hyperoxaluria Type 1, PH1
Study of YOLT-203 in Children and Adults With Primary Hyperoxaluria Type 1 (PH1)
This study will be conducted to evaluate the efficacy and safety of YOLT-203 in children and adults with Primary Hyperoxaluria Type 1.
- Trial name
- NCT07587021
- Testing
- YOLT-203
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- YolTech Therapeutics Co., Ltd
Urinary Stones, Prostate Cancer
Development of an AI-Agent for Urological Disease Diagnosis and Treatment
Urological diseases such as urinary stones, prostate cancer, and bladder cancer are very common and often require highly specialized diagnosis and treatment.
- Conditions
- Urinary Stones, Prostate Cancer, Bladder Cancer
- Trial name
- NCT07721935
- Where
- 3 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Nephrolithiasis, Kidney Stone
Observational Approach Versus Surgical Intervention for Stones
The aims of the Observational Approach versus Surgical Intervention for Asymptomatic Stone (OASIS) trial are: 1) to determine whether observation compared to upfront surgery results in less healthcare-related life disruption due…
- Trial name
- OASIS (NCT07718802)
- Testing
- Surgery, Observation
- Where
- 4 sites in United States
- Volunteers
- 1,658 people
- Sponsor
- Children's Hospital of Philadelphia
Kidney Stone, Pain, Postoperative
Meditation Effects on Discomfort, Pain InTerference, and AnxieTy After urEteroscopy
The goal of this pilot clinical trial is to learn whether meditation can help improve recovery in children and adults having surgery for kidney stones.
- Conditions
- Kidney Stone, Pain, Postoperative, Anxiety Postoperative
- Trial name
- MEDITATE (NCT06783946)
- Testing
- Meditation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Urolithiasis, Stone, Kidney
Registry of MIUS for Urolithiasis (ReMIUS-U)
The purpose of this registry is to collect data on patients who have undergone minimally invasive treatments for urinary system stone disease, including percutaneous nephrolithotomy (PCNL), shock wave lithotripsy (SWL)…
- Conditions
- Urolithiasis, Stone, Kidney, Stone Ureter, Complication of Surgical Procedure
- Trial name
- ReMIUS-U (NCT06394908)
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Marmara University