Clinical trials: Calculus
Urolithiasis, Kidney Stones
Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control
This is a prospective randomized trial to study the effect of assigning the control of the fluoroscopic x-ray activation to the surgeon as compared to the radiation technologist.
- Trial name
- NCT02224287
- Testing
- Technologist control of fluoroscopy, Surgeon control of fluoroscopy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Determine the Efficacy and Safety of SWL in Renal Stones Larger Than 2 cm in Pediatric Age Group
Extracorporeal Shock Wave Lithotripsy for Treatment of Large Pediatric Renal Pelvic Stone Burden More Than 2 cm
Extracorporeal shock wave lithotripsy (SWL) was first described for pediatric nephrolithiasis in 1986; SWL has been a mainstay of treatment for both renal and ureteral calculi in children .
- Trial name
- NCT05293613
- Testing
- extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Fibrodysplasia Ossificans Progressiva, FOP
A Study to Investigate the Safety, Pharmacokinetics (PK), and Efficacy of Garetosmab in Children and Adolescents With Fibrodysplasia Ossificans Progressiva (FOP)
This study is researching an experimental drug called garetosmab, referred to as "study drug". The study is focused on children and adolescent participants with FOP.
- Trial name
- OPTIMA-2 (NCT07559513)
- Testing
- garetosmab
- Volunteers
- 18 people
- Sponsor
- Regeneron Pharmaceuticals
Benign Prostate Hypertrophy(BPH), Renal Calculi
Stone and Laser Therapies Post-Market Study (SALT)
The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g.…
- Conditions
- Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary
- Trial name
- SALT (NCT06982235)
- Testing
- Ureteroscope system, Laser system
- Where
- 5 sites in United States
- Volunteers
- 238 people
- Sponsor
- Boston Scientific Corporation
Primary Hyperoxaluria Type 3
Natural History of Patients With PH3 and a History of Stone Events
This is a natural history study of adults, adolescents, and children (starting at birth) with genetically confirmed primary hyperoxaluria type 3 (PH3) who have a history of stone events during the last 3 years and/or the presence…
- Trial name
- PHYOX-OBX (NCT04542590)
- Where
- 6 sites in United States, Canada and 3 more
- Volunteers
- 7 people
- Sponsor
- Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Kidney Stone
SEARCH FOR OPTIMAL ANAESTHESIA IN RETROGRADE INTRARENAL SURGERY
Patients undergoing retrograde intrarenal surgery for kidney stones from November 2017 to May 2018 were prospectively recruited to participate in the study.
- Trial name
- NCT03999255
- Testing
- combined respiratory support (CRS)
- Where
- Russia
- Volunteers
- 38 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Calculi, Renal, PCNL
Preoperative Prophylactic Fosfomycin Trometamol Versus 5-day Levofloxacin in Prevention of Postpercutaneous Nephrolithotomy Infectious Complications and Sepsis.
A randomized controlled trial comparing the use of preoperative prophylactic single dose fosfomycin trometamol versus levofloxacin in prevention of post-PCNL infectious complications and sepsis.
- Conditions
- Calculi, Renal, PCNL, Infectious Complications
- Trial name
- NCT07355907
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Tanta University
Kidney Stone
Comparison of Efficacy of Intercostal Nerve Block vs Peritract Infiltration With 0.25% Bupivacaine in PCNL
Percutaneous nephrolithotomy (PCNL) is the preferred treatment for renal stones >2 cm or resistant to ESWL. Postoperative pain following this invasive surgery adds to the morbidity of patient which requires additional analgesia…
- Trial name
- NCT04835922
- Testing
- Intercostal Nerve Block, Peritract Infiltration
- Where
- Nepal
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Teen Pregnancy Prevention
Evaluation of Stepping Stones
The goal of this randomized trial is to learn if the Stepping Stones (StSt) intervention has a positive impact on the sexual health and relationship behaviors of sexually active youth between the ages of 12 and 22 years old who…
- Trial name
- StSt (NCT06574217)
- Testing
- Stepping Stones (StSt), Like
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The Policy & Research Group
Calculi
A Randomised Controlled Clinical Trial on the Use of a Dental Aerosol Box to Prevent Microbial Transmission During Dental Procedure
The study compares the use of a dental aerosol box in preventing microbial transmission during dental procedure. Subjects requiring scaling treatment (BPE 2) will be recruited.
- Trial name
- NCT05034705
- Testing
- Conventional suction system, Dental aerosol box with modified high volume evacuation system
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cholecystitis; Gallstone
Intraoperative Spillage of Bile and Gallstones During Laparoscopic Cholecysetectomy
1. determine the most important factors which is responsible for the outcome post bile and gallstones spillage during laparoscopic cholecystectomy 2. the management of complications of bile and gallstones spillage
- Trial name
- NCT04041726
- Volunteers
- 30 people
- Sponsor
- Assiut University
Pancreatic Duct Stone
Safety and Efficacy of P-ESWL and ERCP
To determine the types, incidence and risk factors of adverse events after pancreatic extracorporeal shock wave lithotripsy (P-ESWL) and endoscopic retrograde cholangiopancreatography (ERCP), define the grading criteria of…
- Trial name
- NCT05916547
- Testing
- pancreatic extracorporeal shock wave lithotripsy
- Where
- China
- Volunteers
- 2,071 people
- Sponsor
- Changhai Hospital
Gallbladder and Bile Duct Calculi
Early Versus Late Cholecystectomy After Clearance of Common Bile Duct Stones
Approximately 10-15% of all patients with gallstones have coexisting common bile duct (CBD) stones. However CBD stones can also be formed in the absence of gallbladder stones.
- Trial name
- ERCP (NCT02460315)
- Testing
- early cholecystectomy, late cholecystectomy
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Homeless Youth Study - Stepping Stone 2.0
Housing instability is both a cause and consequence of mental health problems. As such youth experiencing housing instability (e.g., homeless or marginally housed) have higher rates of mental health problems.Because of their…
- Trial name
- NCT03776422
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Cholelithiases
Does Early Laparoscopic Cholecystectomy After ERCP Reduce the Risk of Complications
Gallstones have been recognised since antiquity and have been found during autopsies of Egyptian mummies. Following the first successful open cholecystectomy in 1882, it was Eric Muhe, a German surgeon, who performed the first…
- Trial name
- NCT06311305
- Testing
- Early Laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Gallbladde Stones
Conventional SILS vs Harmonic Scalpel SILS
Single incision laparoscopic cholecystectomy is gaining widespread acceptance. there are some obstacles making this procedure more complex than conventional laparoscopic cholecystectomy.
- Trial name
- SILS (NCT01272505)
- Testing
- converntional SILC, Harmonic scalpel Single incision laparoscopic cholecystectomy
- Where
- Egypt
- Volunteers
- 137 people
- Sponsor
- Mansoura University
Stone;Renal
Flexible Ureteroscopy Versus Mini-Percutaneous Nephrolithotomy for Treatment of Renal Stones
Management of nephrolithiasis is evolving rapidly, and various minimally-invasive urological procedures are currently available for treating patients with renal stones, including extracorporeal shockwave lithotripsy (ESWL)…
- Trial name
- NCT03932370
- Testing
- Flexible ureteroscopy, mini-Percutaneus nephrolithotomy
- Where
- Egypt
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gallstone Disease
GallRiks ERC Anesthesia Study
Endoscopic retrograde cholangiopancreatography (ERCP) for common bile duct stones (CBDS) removal can be performed under varying levels of sedation.
- Trial name
- NCT07205380
- Testing
- Endoscopic Retrograde Cholangiopancreaticography
- Volunteers
- 121,252 people
- Sponsor
- Karolinska Institutet
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Renal Stones, Calculus
Comparison of ESWL and Mini-PCNL for High-Density Renal Stones in Children
Pediatric nephrolithiasis is an increasing health problem, with rising prevalence particularly in certain geographic regions. Management options for pediatric renal stones include extracorporeal shockwave lithotripsy (SWL)…
- Conditions
- Renal Stones, Calculus, Pediatric, Endoscopy
- Trial name
- NCT07360041
- Testing
- Miniaturized Percutaneous Nephrolithotomy (mini-PNL), Shock Wave Lithotripsy (SWL)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University