Clinical trials: Cancer-Related Condition
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma
This phase II trial studies how well an umbilical cord blood transplant with added sugar works with chemotherapy and radiation therapy in treating patients with leukemia or lymphoma.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia, Acute Lymphoblastic Leukemia
- Trial name
- NCT03096782
- Testing
- Anti-Thymocyte Globulin, Busulfan, Clofarabine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
Conscripts, Military Induction Board
Prevalence of ENT Diseseas
The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of…
- Conditions
- Conscripts, Military Induction Board, ENT Disease, Rhinosinusitis Chronic
- Trial name
- PrENT (NCT06105346)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Neoplasms, Fatigue
Self-Management of Cancer-Related Fatigue by Adolescents
This study will investigate self-management of cancer-related fatigue by adolescents through pilot study of an evidence based educational resource.
- Trial name
- NCT00862186
- Testing
- 'Fatigue Facts & Fixes'
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Seattle Children's Hospital
Breast Cancer
Study of Biomarkers in Tissue Samples From Patients With Breast Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT01004796
- Testing
- cytogenetic analysis, microarray analysis, mutation analysis
- Sponsor
- University of Wisconsin, Madison
Cardiovascular Diseases, B-cell Acute Lymphoblastic Leukemia
CAR T Cell Therapy Related Cardiovascular Outcomes
This will be a cohort study of all patients receiving Cluster of Differentiation 19 (CD19)-specific CAR T cell therapy for relapsed/refractory B cell haematological malignancies.
- Conditions
- Cardiovascular Diseases, B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma Refractory, B-cell Lymphoma Recurrent
- Trial name
- CARTCO (NCT05130489)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University College London Hospitals
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Dextromethorphan in Treating Patients With Fatigue Caused by Cancer
RATIONALE: Dextromethorphan may help relieve fatigue in patients with cancer. PURPOSE: This clinical trial is studying how well dextromethorphan works in treating patients with fatigue caused by cancer.
- Conditions
- Fatigue, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
- Trial name
- NCT00176540
- Testing
- dextromethorphan hydrobromide
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Pediatric Cancer, Nausea With Vomiting Chemotherapy-Induced
The Effect of Acupressure Chemotherapy-related Nausea Vomiting in Children
This study is carried out to evaluate and compare the efficiency of acupressure practice applied with pressure or sea-band and their placebo on managing the acute nausea-vomiting symptoms developing due to chemotherapy in…
- Trial name
- NCT04651608
- Testing
- manuel acupressure, sea-band acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Akdeniz University
Leukemia
Radiolabeled Monoclonal Antibody, Cyclophosphamide, and Total Body Irradiation Followed By Donor Stem Cell Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia
RATIONALE: Radiolabeled monoclonal antibodies can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00003868
- Testing
- cyclophosphamide, methotrexate, allogeneic bone marrow transplantation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Fred Hutchinson Cancer Center
Cancer, Cardiotoxicity
Role of Aerobic Exercise to Modulate Cardiotoxicity in Long Term Cancer Survivors Exposed to Anthracycline Therapy
Over 50% of the more than 270,000 childhood cancer survivors in the U.S. have been treated with anthracyclines and thus are at risk of developing cardiotoxicity.
- Trial name
- NCT04036032
- Testing
- Exercise program
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- Connecticut Children's Medical Center
Renal Cell Cancer
Conditioning Regimen in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Primary Objectives: 1. To compare the overall survival of metastatic renal cell carcinoma (RCC) patients undergoing HLA-matched related donor nonmyeloablative allogeneic hematopoietic stem cell transplantation (NST) using…
- Trial name
- NCT00429026
- Testing
- Fludarabine, Melphalan, Cyclophosphamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Cancer, EBV Infection
Relationship of EBV-positive Gastric Cancer and Multiple Genes Associated With Gastric Carcinogenesis
The data of 460 gastric cancer patients who underwent curative gastrectomy with D2 lymph node dissection between January 2017 and February 2022 were analyzed.
- Conditions
- Gastric Cancer, EBV Infection, MSI
- Trial name
- NCT05604378
- Testing
- Gastrectomy
- Where
- South Korea
- Volunteers
- 460 people
- Sponsor
- Saint Vincent's Hospital, Korea
Neoplasms
Determinants of Physical Activity Level in Pediatric Oncological Patients Treated With Cardiotoxic Therapy - a Study Protocol
Cancer treatment in children is generally effective, but unfortunately, it often comes with side effects-unwanted negative impacts.
- Trial name
- NCT06256068
- Volunteers
- 300 people
- Sponsor
- Medical University of Warsaw
Pulmonary Fibrosis, Breast Cancer
Trial of Concurrent Versus Sequential Tamoxifen With Radiotherapy in Breast Cancer Patients
Two hundred and sixty patients with breast cancer will be accrued into the study. After inclusion in the study, all the patients will be randomized into two arms.
- Trial name
- CONSET (NCT00896155)
- Testing
- Tamoxifen, Radiotherapy
- Where
- India
- Volunteers
- 260 people
- Sponsor
- Tata Memorial Hospital
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Pancreatic Cancer, Neoadjuvant
An Exploration of Candidates for Neoadjuvant Treatment in Resectable Pancreatic Cancer
An Exploration of Candidates for Neoadjuvant Treatment in Resectable Pancreatic Cancer
- Trial name
- NCT06129812
- Testing
- Neoadjuvant treatment
- Volunteers
- 1,132 people
- Sponsor
- Seoul National University Hospital
Cardiotoxicity, Acute Myeloid Leukemia in Children
Prevention of Chemotherapy Induced Cardiotoxicity in Children With Bone Tumors and Acute Myeloid Leukemia
Prevention and early detection of chemotherapy-induced cardiotoxicity in children with bone tumors and Acute Myeloid Leukemia by giving capoten
- Conditions
- Cardiotoxicity, Acute Myeloid Leukemia in Children, Bone Tumor
- Trial name
- NCT03389724
- Testing
- Capoten®
- Where
- Egypt
- Volunteers
- 245 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Breast Cancer
Association of Dihydropyrimidine Dehydrogenase (DPYD) Variants With Toxicity Related to Capecitabine
The goal of this laboratory research study is to identify possible differences in a gene among patients with breast cancer that cannot be treated by surgery.
- Trial name
- NCT00478686
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- M.D. Anderson Cancer Center
Lymphoma, Leukemia
Immunotherapy With NK Cell, Rituximab and Rhu-GMCSF in Non-Myeloablative Allogeneic Stem Cell Transplantation
The goal of this clinical research study is to find out if giving a boost of natural killer (NK) cells from a donor combined with Rituxan (rituximab), can help to control disease in patients who have already received an…
- Conditions
- Lymphoma, Leukemia, Transplantation, Stem Cell, Lymphoid Malignancies
- Trial name
- NCT00383994
- Testing
- GM-CSF, Rituximab, NK Cell Infusion
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- M.D. Anderson Cancer Center
HPV Infection, HPV-Related Cervical Carcinoma
A Randomized, Blinded, Placebo-controlled Phase I Clinical Trial Evaluating the Safety and Preliminary Immunogenicity of a 11-valent Recombinant Human Papillomavirus Vaccine (Hansenulapolymorpha) in Chinese Women Aged 9-45 Years
A total of 90 Chinese women aged 9-45 years old were divided into three age groups: 27-45 years old, 18-26 years old, and 9-17 years old. The experimental group and the placebo group were randomly assigned in a ratio of 2:1.
- Trial name
- NCT04083196
- Testing
- 11-valent recombinant human papilloma virus vaccine (Hansenula polymorpha)
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Vaccine and Serum Institute, China
Leukemia, Lymphoma
Interleukin-2 Following Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill cancer cells. PURPOSE: Phase I trial to study the effectiveness of interleukin-2 following bone marrow transplantation in treating patients who have…
- Conditions
- Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003962
- Testing
- aldesleukin
- Where
- United States
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins