Clinical trials: Carbon Dioxide
Anesthesia
A New and Innovative Method for CO2 Removal in Anesthetic Circuits
The drawbacks of chemical CO2 absorbers include the production of compounds harmful to patients that also lead into increased cost and environmental impact, as well as the daily disposal of compound special waste.
- Trial name
- memsorb (NCT03014336)
- Testing
- memsorb
- Where
- 2 sites in Canada
- Volunteers
- 286 people
- Sponsor
- DMF Medical Incorporated
Healthy, Hypercapnia
Role of Prostaglandins in the Regulation of Brain Blood Flow
This study will use magnetic resonance imaging (MRI) to examine the role of prostaglandins-a type of fatty acid with hormone-like actions-in the regulation of brain blood flow.
- Trial name
- NCT00006318
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Child, Only, Brain Diseases
Metabolic and Hemodynamic Reserve in Pediatric SCA
The purpose of this research study is to better understand how blood flow and metabolism change can influence brain development in the early decades of life.
- Conditions
- Child, Only, Brain Diseases, Sickle Cell Disease, Anemia, Sickle Cell
- Trial name
- NCT04406818
- Testing
- Carbon Dioxide
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Alopecia Areata
Efficacy of Fractional CO2 Laser as a Mono- or Adjuvant Therapy for Alopecia Areata
Alopecia areata is a non-scarring hair loss disorder that affects both sexes equally. Incidence of the disease varies for different populations and in different studies, with global incidence ranging from 0.57% to 3.8%.
- Trial name
- NCT04003376
- Testing
- fractional carbon dioxide laser alone, Triamcinolone Acetonide 10mg/mL, platelet rich plasma
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Respiratory Distress Syndrome, Preterm Birth
nHFOV vs nCPAP: Effects on Gas Exchange for the Treatment of Neonates Recovering From RDS
The purpose of this study is to compare the effects of two different techniques of non-invasive ventilation (nCPAP and nHFOV) on gas exchange in preterm infants recovering from respiratory distress syndrome.
- Trial name
- NCT02772835
- Testing
- Medin-cno
- Where
- 8 sites in Italy, Lithuania
- Volunteers
- 30 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Sleep Disorder; Breathing-Related, Central Apnea
Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular Disease
There is an unmet demand for the evaluation of nocturnal hypoventilation in children with NMD. An ambulatory screening tool that can reliably facilitate timely diagnosis and treatment in these children would be invaluable.
- Conditions
- Sleep Disorder; Breathing-Related, Central Apnea, Neuromuscular Diseases, Obstructive Sleep Apnea
- Trial name
- NCT03478566
- Testing
- Transcutaneous CO2 monitoring
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- The Hospital for Sick Children
Intubated Neonates That Require Conventional Ventilation
Comparison of Open Versus Masked Distal EtCO2 Monitoring of Neonates Ventilated With Conventional Ventilation
Primary: The purpose of this study is to assess the clinical implications of continuous distal CO2 monitoring when used for clinical decisions Sub Study: Evaluate the average life time (duration) of Standard Carinal VitaLine set…
- Trial name
- NCT01572272
- Where
- 3 sites in Israel
- Volunteers
- 66 people
- Sponsor
- Oridion
Intraoperative Ventilation
Arterial to End-Tidal Carbon Dioxide Difference During Pediatric Laparoscopic Surgeries
Studying the arterial to end-tidal carbon dioxide difference in children undergoing laparoscopic surgeries under different intra-abdominal pressures is of extreme importance.
- Trial name
- PaCO2-EtCO2 (NCT03361657)
- Where
- Egypt
- Volunteers
- 29 people
- Sponsor
- Assiut University
Neonatal Resuscitation, Neonatal Disease
Pedi-Cap CO2 Detector for Face-mask Ventilation in the Delivery Room
The goal of this study is to determine if using a Pedi-Cap (a type of colorimetric carbon dioxide detector) during face mask ventilation (PPV) for newborn infants in the delivery room will lower the time of PPV needed.
- Trial name
- CO2-Vent (NCT06258187)
- Testing
- Pedi-Cap
- Where
- United States
- Volunteers
- 632 people
- Sponsor
- University of Texas Southwestern Medical Center
Cervical Carcinoma, Dyspareunia
Fractional CO2 Laser Therapy in Minimizing Genitourinary Syndrome of Menopause in Gynecological Cancer Survivors
This randomized pilot trial studies how well fractional carbon dioxide (CO2) laser therapy works in minimizing genitourinary syndrome of menopause (GSM) in gynecological cancer survivors.
- Conditions
- Cervical Carcinoma, Dyspareunia, Endometrial Carcinoma, Ovarian Carcinoma
- Trial name
- NCT03372720
- Testing
- Laser Therapy, Questionnaire Administration
- Where
- 4 sites in United States
- Volunteers
- 19 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Anesthesia, Hypercapnia
End Tidal Carbon Dioxide Concentration and Depth of Anesthesia in Children
Carbon Dioxide (CO2) is a by-product of metabolism and is removed from the body when we breathe out. High levels of CO2 can affect the nervous system and cause us to be sleepy or sedated.
- Conditions
- Anesthesia, Hypercapnia, Hypocapnia
- Trial name
- NCT06303518
- Testing
- High normal ETCO2: ETCO2 50 mmHg (+/- 3mmHg), Normal ETCO2: ETCO2 40 mmHg (+/- 3mmHg), Low Normal ETCO2: ETCO2 30 mmHg (+/- 3mmHg)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia
Relationship Between EIT and Respiratory Status in Very Preterm Infants
Electrical Impedance Tomography (EIT) is a non-invasive imaging technique that can measure lung function in real time. This study will follow premature infants to see if EIT can help predict which infants will be successful in…
- Conditions
- Chronic Lung Disease of Prematurity, Bronchopulmonary Dysplasia, Premature Lungs
- Trial name
- NCT06609135
- Testing
- Sentec LuMon Device (EIT system), Sentec Digital Monitoring System (transcutaneous CO2 monitor)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lawrence Rhein
Critical Lower Limb Ischemia, Abdominal Aortic Aneurysms
The Use of Carbon Dioxide as a Contrast Media for Performing Endovascular Procedures
Prospective randomized comparison between endovascular procedures performed with iodinated contrast or carbon dioxide as intraarterial contrast.
- Trial name
- NCT01861327
- Testing
- CO2, Iodine contrast media
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Nelson Wolosker
Panic Disorder
CO2 Inhalation and Risk for Panic Disorder
Objective: To examine respiratory/physiological and subjective responding as well as genetic transmission among offspring of parents with a history of or current panic disorder (PD) diagnosis to determine whether…
- Trial name
- NCT00930657
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- National Institute of Mental Health (NIMH)
Squamous Intraepithelial Lesions, Laser Burn
Research of Laser Ablation for the Treatment of Lower Anogenital Tracts' Precancerous Lesions
Using multiple targeting CO2 laser ablation to treat the precancerous lesion of the female lower anogenital tracts and analyzing the data collected in the study, we aim to form the standard strategy of laser ablation method to…
- Trial name
- NCT05170620
- Testing
- laser ablation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tongji Hospital
Colonic Adenomatous Polyps
Effectiveness and Safety of the Colonoscopy With "Visualization" Balloon
Colonoscopy has become the "gold standard" in detection of colonic polyps and colon cancer. However, colonoscopy causes significant abdominal discomfort and abdominal pain during and after the procedure, requiring intravenous…
- Trial name
- NCT02117232
- Testing
- Visualization balloon, Traditional CO2 insufflation colonoscopy
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Mercy Medical Center
Carbon Dioxide Partial Pressure Determination, Transcutaneous
TCOM Ring Evaluation
Subjects that are currently on a transcutaneous carbon dioxide monitor (TCOM) to monitor the carbon dioxide level in their blood will be placed on an additional TCOM using a non-adhesive sensor application ring instead of the…
- Trial name
- NCT05640973
- Testing
- Evaluation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Gastrostomy
CO2 vs Air Insufflation in Children Undergoing PEG
Ap¬plications of CO2 insufflation for endoscopic procedures have been reported for the performance of routine colonoscopy, small bowel endoscopy, endoscopic retro¬grade cholangiopancreatography (ERCP) and endoscopic submucosal…
- Trial name
- NCT04714021
- Testing
- CO2, air
- Where
- 7 sites in Belgium, Croatia and 5 more
- Volunteers
- 120 people
- Sponsor
- University Medical Centre Ljubljana
Autologous Fat Graft Harvesting, SVF-gel Preparation and Filling, CO2 Fractional Laser Treatment by Using Acupulse Device
Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment
Background Adipose extracellular matrix/stromal vascular fraction gel（SVF-gel）, which contains adipose-derived stem cells, endothelial cells, smooth muscle cells, pericytes, and other cell components.
- Trial name
- NCT06116162
- Testing
- SVF-gel Filling and CO2 fractional laser
- Where
- 2 sites in China
- Volunteers
- 18 people
- Sponsor
- Xijing Hospital
Newborn Infant
Confirmation of Correct Tracheal Tube Placement in Newborn Infants - a Randomized Control Trial
Most premature babies have difficulty breathing at birth and need help (resuscitation). The treatment for this is to gently inflate their lungs with a resuscitation device and a facemask.
- Trial name
- NCT01870622
- Testing
- Flow waves, ECO2
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Alberta