Clinical trials: Carbon Dioxide
Laryngeal Diseases, Pharyngeal Diseases
ENT FiberLase CO2 Study
This study is intended to collect data regarding treatment with a new flexible fiber used to transmit laser emitted from a Carbon dioxide (CO2) laser to the transoral region.
- Trial name
- NCT01276418
- Testing
- CO2 laser
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 49 people
- Sponsor
- Lumenis Be Ltd.
Surgery--Complications
Association of the Arteriovenous Difference in Carbon Dioxide and Its Relation to the Difference in Arteriovenous Oxygen Content With the Occurrence of Postoperative Complication
Intra-operative hemodynamic management in high-risk surgery is a priority for the anesthesiologist. The current strategy is based on the continuous measurement of cardiac output and its maximization by vascular filling has many…
- Trial name
- CARBODAV (NCT03914976)
- Testing
- patient having to undergo a high risk programmed digestive surgery
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Scarring
Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face
The purpose of this study is to evaluate the efficacy of dHACM (Dehydrated Human Amnion Chorion Membrane) for reducing time to healing when used in post-laser recovery following ActiveFX™ and DeepFx™ fractionated ablative CO2…
- Trial name
- NCT01995604
- Testing
- Application of Sterile 0.9% Saline Solution, Application of dHACM
- Where
- United States
- Sponsor
- MiMedx Group, Inc.
Critical Illness, Ventilation Perfusion Mismatch
Arterial and End-Tidal CO2 Gradient as a Mortality Predictor in Critical Care Patients
Scoring systems (SOFA, APACHE-II etc.) are used to estimate the mortality rates of patients treated in the intensive care unit. . In the scoring systems used, the disfunction level of the organs of the patients is measured.
- Conditions
- Critical Illness, Ventilation Perfusion Mismatch, Shock, Pulmonary Embolism
- Trial name
- NCT05341258
- Testing
- EtCO2, PaCO2
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Breast Cancer, Mastectomy
Patient Activated Controlled Expansion (PACE) Trial
The purpose of this study is to determine whether a patient controlled tissue expander can improve the results and patient experience in breast reconstruction.
- Conditions
- Breast Cancer, Mastectomy, Breast Reconstruction
- Trial name
- PACE (NCT01009008)
- Testing
- Patient Activated Controlled Expansion Device
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- AirXpanders, Inc.
Asthma
The Asthma Breathing Record Study
The study involves a new device, called 'N-Tidal C', which uses a method that has the potential to predict when asthma attacks are about to happen. The device works by accurately measuring an individual's exhaled CO2 waveform.
- Trial name
- ABRS (NCT04504838)
- Where
- United Kingdom
- Volunteers
- 124 people
- Sponsor
- TidalSense
Gastro Intestinal Bleeding
The Value of End-tidal Capnography in Gastrointestinal Bleeding
Gastrointestinal bleeding is a condition that frequently presents to emergency departments and can be fatal if diagnosis and treatment are delayed.
- Trial name
- NCT06345456
- Testing
- End-tidal capnography
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people
- Sponsor
- Izmir Katip Celebi University
Colonic Adenoma, Water Exchange Colonoscopy
Adenoma Miss Rate With Water Exchange vs Carbon Dioxide Colonoscopy
This was an observational study comparing consecutive group of WE and CO2 insufflation in terms of right and proximal colon AMR by tandem colonoscopy.
- Trial name
- NCT03832322
- Testing
- Water exchange colonoscopy, CO2 insufflation colonoscopy
- Where
- Taiwan
- Volunteers
- 176 people
- Sponsor
- Evergreen General Hospital, Taiwan
Esophageal Motility Disorders
U-POEM vs CO2-POEM
Multicenter randomized trial comparing post-procedural pain intensity after Per-Oral endoscopic myotomy (POEM) between two types of standard of care insufflation methods (CO2 vs Underwater).
- Trial name
- U-POEM (NCT06918730)
- Testing
- U-POEM, CO2-POEM
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- AdventHealth
Hypoxemia
Capnography Monitoring During Intravenous Conscious Sedation Sedation With Midazolam for Oral Surgery
Dentists use sedation to help patients accept difficult procedures and to relieve anxiety. During sedation, the well-being of the patient is monitored by the dental team.
- Trial name
- NCT01949012
- Testing
- Capnography
- Where
- Ireland
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University College Cork
Ischemic Stroke, Acute, Thrombectomy
CO2 Modulation in Endovascular Thrombectomy for Acute Ischemic Stroke
Acute ischemic stroke due to large vessel occlusion is responsible of cerebral blood flow impairment with a progressive and extensive ischemic process.
- Conditions
- Ischemic Stroke, Acute, Thrombectomy, Anesthesia, General, Cerebrovascular Circulation
- Trial name
- COMET-AIS (NCT05051397)
- Testing
- HYPERCAPNIA, NORMOCAPNIA
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cardiovascular Disease
Accuracy of Non-invasive Effective Pulmonary Perfusion Measurement by CO2
Cardiac output monitoring is mandatory in most surgical and critical care patients. Many techniques to assess cardiac output are invasive and/or have many limitations, contraindications and drawbacks.
- Trial name
- NCT02382120
- Where
- Argentina
- Volunteers
- 30 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Vaginal Atrophy
A Clinical Clinical Observation of CO2 Fractional Laser in Female Vaginal Repair
1. Vaginal atrophy is the most common indication in the treatment of vaginal rejuvenation. Its main manifestation is vaginal relaxation syndrome, which may be the early symptom of female pelvic floor dysfunction.
- Trial name
- NCT04492176
- Testing
- CO2 fractional laser（ACUPULSE,Lumenis）
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Hypertension, Pulmonary, Hypertension;Pulmonary;Primary
Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension
Measurement of the endtidal carbon dioxide by capnography to exclude or to ensure the diagnosis pulmonary hypertension. The aim of the study is to obtain an endtidal carbon dioxide cut-off value for the diagnostic algorithm for…
- Conditions
- Hypertension, Pulmonary, Hypertension;Pulmonary;Primary, Chronic Thromboembolic Pulmonary Hypertension, Vascular Diseases
- Trial name
- EARLIER (NCT03388476)
- Testing
- Capnography
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Laser Burn
Vaginal Elasticity Assessment Before and After Vaginal Carbon Dioxide Laser Treatment.
Female patients with either stress urinary incontinence (SUI) or vaginal wall weakness and prolapse will be evaluated for vaginal elasticity using vaginal tactile imaging both before and after Carbon Dioxide laser treatment.
- Trial name
- NCT03630406
- Testing
- Vaginal Tactile Imaging
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Rambam Health Care Campus
Vulvovaginal Candidiasis, Genital, Laser Therapy
A Protocol for the Role of Fractional CO2 Laser in Consolidation Treatment of Recurrent Vulvovaginal Candidiasis
Background: Recurrent vulvovaginal candidiasis (RVVC) is a common obstinate vulvovaginal inflammation in gynecology. At present, the pathogenesis of RVVC is not clear.
- Trial name
- NCT04292704
- Testing
- the fractional CO2 laser, Clotrimazole
- Where
- China
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
Acute Respiratory Distress Syndrome
Low-Flow CO2 Removal for Mild to Moderate ARDS With PRISMALUNG
This pilot observational study will assess changes in pH /PaO2 /PaCO2, Respiratory Rate and device CO2 clearance in the first 24 hours of Extracorporeal CO2 removal (ECCO2R) following tidal volume (Vt), and plateau pressure…
- Trial name
- NCT02606240
- Testing
- CO2 removal with PRISMALUNG in ARDS
- Where
- 5 sites in France
- Volunteers
- 20 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Colonoscopy, Children
Insufflation in Children Undergoing Colonoscopy
Studies in adults have shown that post-procedural abdominal pain is reduced with the use of CO2 instead of air for insufflation during colonoscopy.
- Trial name
- NCT02407639
- Testing
- CO2, air
- Where
- Slovenia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Sleep Apnea, Elderly Adults
Sleep Apnea in Elderly
Sleep-disordered breathing (SDB or sleep apnea) is very common among elderly Veterans and leads to increased morbidity and mortality in this population.
- Trial name
- NCT02703220
- Testing
- Hyperoxia/oxygen, Acetazolamide, Finasteride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development