Clinical trials: Cardiac Bypass Patients
Heart Failure, CAD - Coronary Artery Disease
Risk Stratification of MACE in Heart Failure Patients Who Undergoing CABG
PROFILE-HF is a multicenter, observational, prospective study of the clinical course and outcomes of chronic heart failure (HF) and coronary artery disease (CAD) in patients undergoing coronary artery bypass grafting (CABG).
- Conditions
- Heart Failure, CAD - Coronary Artery Disease, CABG
- Trial name
- PROFILE-HF (NCT07480915)
- Where
- Russia
- Volunteers
- 160 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Ischemic Heart Disease, Atherosclerosis
Graft Patency as a Predictor of Health-related Quality of Life.
The health-related quality of life questionnaire "EQ-5D" has been collected in connection with several interventional and observational studies where the no-touch vein harvesting technique in CABG has been used.
- Trial name
- NCT02547194
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Örebro County Council
Children With Heart Defects
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass.
Heparin is an anticoagulant or "blood thinner". Heparin is always given to patients undergoing open-heart surgery to prevent blood from clotting when a patient is placed on the heart-lung machine.
- Trial name
- NCT00166140
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Emory University
Open-heart Surgery, Cardiopulmonary Bypass
Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery
Cardiopulmonary bypass is done with a machine that does the work of the heart and lungs during open-heart surgery. This study is to determine if intravenous (i.v.) phenoxybenzamine is safe.
- Trial name
- NCT00569855
- Testing
- Phenoxybenzamine
- Where
- United States
- Volunteers
- 785 people
- Sponsor
- University of Arkansas
Heart Surgery, Ischemic Heart Disease
Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB
Enhanced recovery after surgery protocols aim to optimize perioperative care and improve surgical outcomes. Preoperative carbohydrate loading has demonstrated benefits in reducing insulin resistance and improving patient…
- Trial name
- CLDM-CABG (NCT06951308)
- Testing
- Carbohydrate loading before surgery
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Cardiac Disease
FEIBA to Optimize Postcardiopulmonary Bypass Hemostasis in Pediatric Cardiac Patients
The purpose of this research is to understand if the medication called FEIBA helps to stop bleeding and decrease transfusion of blood products to small children operated on the heart.
- Trial name
- NCT05020483
- Testing
- FEIBA
- Sponsor
- Mayo Clinic
Cardiac Surgery, Cardiopulmonary Bypass
Pentastarch Use in Cardiac Surgery
Patients undergoing cardiac surgery with cardiopulmonary bypass require significant fluid administration. Fluids are used routinely to replace blood lost during and after surgery.
- Trial name
- NCT00182377
- Testing
- Pentastarch (displace either 500 ml or 1000 ml of pump prime with pentastarch)
- Where
- Canada
- Sponsor
- Hamilton Health Sciences Corporation
Acute Kidney Injury
Cost-effectiveness Analyses for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery in the UK
Multi-centre retrospective analysis of prospectively collected data with propensity matched scoring groups (AKI v/s non-AKI). Data collection from databases (or their equivalent): PATS Dendrite, Electronic Medical Records, TD-web…
- Trial name
- Cost-AKI (NCT07108634)
- Testing
- RenalGuard Therapy
- Where
- United Kingdom
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Congenital Heart Diseases
The Protective Effects of Sevoflurane in Pediatric Cardiac Surgery
During repair of a congenital heart defect the child is exposed to myocardial hypoxia. Recent studies have suggested that the paediatric myocardium is more sensitive to hypoxia and cardioplegic arrest than the adult.
- Trial name
- NCT01450956
- Testing
- Sevoflurane, Control
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Cardiopulmonary Bypass
Validation of Near Infrared Spectroscopy (NIRS) During Heart-Lung Bypass in Children
Non-invasive assessment of blood flow to organs has long challenged clinicians. Recently, near infrared spectroscopy (NIRS) has been recognized as a methodology that may achieve this goal.
- Trial name
- NIRS (NCT00745394)
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Surgical Wound Infection, Cystitis
The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study
All surgical procedures carry with them the risk of infection. Even a minor infection can extend the hospitalization after cardiac surgery. The average minimum increase in length of stay for a single infection is three days.
- Conditions
- Surgical Wound Infection, Cystitis, Bacteremia, Pneumonia
- Trial name
- NCT00164099
- Testing
- Synbiotic 2000
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Medical Center
Diabetes Mellitus, Kidney, CPB
Kidney Function in Diabetics During CPB (Cardio Pulmonary Bypass)
Filtration of urine in the kidney requires sufficient oxygen supply. The filtration of urine is greater in patents with diabetes.
- Trial name
- DM-ECC (NCT03405532)
- Testing
- DM-ECC
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
Coronary Artery Bypass Grafting, Preoperative Anxiety
Nurse Navigation Programs Affect to Anxiety, Perception of Quality Nursing Care and Stress Hormone Levels
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery…
- Trial name
- NCT07528989
- Testing
- Nursing navigation program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
Congenital Heart Disease, Sepsis
Pro-Calcitonin Levels Following Pediatric Cardiac Surgery
First, we, the researchers, hope to find out the PCT response to heart surgery in children by taking blood before surgery and each day for four days after surgery.
- Conditions
- Congenital Heart Disease, Sepsis, Infection
- Trial name
- NCT00284570
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Atrial Fibrillation
The Effect of Arrhythmia Surgery on Quality of Life in Patients With Atrial Fibrillation Undergoing Cardiac Surgery
Atrial fibrillation (AF) is connected with an increased morbidity and mortality. In addition, quality of life is diminished due to palpitations, dyspnea, dizziness and syncope.
- Trial name
- NCT00886080
- Testing
- Pulmonary vein isolation using microwave energy
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Lung Injury, Postoperative Complications
Ventilation During Cardiopulmonary Bypass
Postoperative pulmonary dysfunction (PPD) is a widely reported complication of cardiopulmonary bypass (CPB) although there is improvement in perioperative management, that leads to increased morbidity and mortality in cardiac…
- Conditions
- Lung Injury, Postoperative Complications, Pulmonary Collapse
- Trial name
- NCT04962542
- Testing
- ventilation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Coronary Artery Disease
CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries.
- Trial name
- NCT01686100
- Testing
- No touch technique, Conventional technique
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Örebro County Council
Coronary Artery Bypass
Stroke and Carotid-Cerebral Vascular Disease After CABG
Review the data of patients who underwent coronary artery bypass grafting (CABG) at the Department of Cardiovascular Surgery in Ruijin hospital from March 2020 to May 2022, including medical history, head and neck CTA, head CT…
- Trial name
- SCCAB (NCT05036044)
- Where
- China
- Volunteers
- 1,002 people
- Sponsor
- Ruijin Hospital
Cardiac Surgery, Thoracic Surgery
Heart Lung Machine Registry
The HeaLMe post-market clinical follow-up registry is undertaken to evaluate the safety and performance of the index devices Heart Lung Machine HL 40 and Temperature Probes TPO-D-HLM L1.8 Adult / Pediatric in patients undergoing…
- Conditions
- Cardiac Surgery, Thoracic Surgery, Vascular Surgery, Cardiopulmonary Bypass
- Trial name
- HeaLMe (NCT06159517)
- Where
- 3 sites in Italy, Spain
- Volunteers
- 184 people
- Sponsor
- Maquet Cardiopulmonary GmbH