Clinical trials: Cardiac Surgery Recovery
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Heart Surgery, Ischemic Heart Disease
Efficacy of Carbohydrate Loading in Diabetic Type 2 Patients Undergoing CABG Surgery on CPB
Enhanced recovery after surgery protocols aim to optimize perioperative care and improve surgical outcomes. Preoperative carbohydrate loading has demonstrated benefits in reducing insulin resistance and improving patient…
- Trial name
- CLDM-CABG (NCT06951308)
- Testing
- Carbohydrate loading before surgery
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Neonatal Disease, Post-Surgical Complication
Cardiac Surgery Recovery in Infants Assessed Using Neoneur Feeding System
A prospective non-randomized longitudinal design of 30-40 infants from initiation of oral feeding until discharge to track feeding changes as a potential indicator of surgical recovery.
- Conditions
- Neonatal Disease, Post-Surgical Complication, Cardiac Disease
- Trial name
- NCT06569641
- Testing
- Neoneur Feeding System
- Volunteers
- 35 people
- Sponsor
- Neoneur LLC
Complex Congenital Heart Disease, Enhanced Recovery After Surgery
The Application of Enhanced Recovery After Surgery (ERAS) for Cardiovascular Surgery in the Correction of Complex Congenital Heart Disease
This study is a multicenter, stepwise design, cluster randomized controlled trial. Random sequence is generated by computer, and each center enters the intervention expectation (Phase I) in random order to implement ERAS…
- Trial name
- NCT05914103
- Testing
- ERAS
- Where
- 2 sites in China
- Volunteers
- 3,030 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Heart Defects, Congenital, Hyperglycemia
SPECS: Safe Pediatric Euglycemia in Cardiac Surgery
Critically ill children, including children undergoing heart surgery, commonly develop elevated blood glucose (also known as "blood sugar") levels during their illness, which can lead to poor health outcomes and an increased risk…
- Trial name
- SPECS (NCT00443599)
- Testing
- Insulin, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 989 people
- Sponsor
- Boston Children's Hospital
Postoperative Pain
Paravertebral Block for Postoperative Analgesia in Children Undergoing Lateral Incision Cardiac Surgery With CBP
This study aims to compare the effect of paravertebral block and local infiltration anesthesia on postoperative analgesia in children undergoing lateral incision cardiac surgery with cardiopulmonary bypass.
- Trial name
- NCT06312904
- Testing
- paravertebral block, Local infiltration anesthesia
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease, Coronary Stenosis
Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG/OPCAB)
It has been assumed that some elements of the ERAS protocol may contribute to the reduction of complications and improve the satisfaction of patients undergoing coronary artery bypass surgery.
- Trial name
- NCT03956420
- Testing
- Premedication visit, Preoperative period, Postoperative period
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Silesian University of Medicine
Atrial Fibrillation
Biatrial Contractility Recovery After Maze
This study aimed at evaluating multiple aspects of biatrial contractility recovery after modified maze procedure during mitral valve surgery.
- Trial name
- NCT02303652
- Testing
- Radiofrequency maze procedure, Transthoracic echocardiography
- Volunteers
- 122 people
- Sponsor
- Centro Cardiologico Monzino
Neonatal Patients Undergoing Major Non-cardiac Surgery, Congenital Anomaly
Neonatal Enhanced Recovery After Surgery (ERAS) Outcomes Study
The goal of this observational study is to improve the way newborn babies are cared for before, during, and after major surgery. Surgery can be very stressful on a baby's body.
- Trial name
- NEO (NCT07771478)
- Testing
- Pre-nERAS Guideline Implementation Intervention, Multifaceted Implementation of nERAS Guideline Intervention
- Where
- 3 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Hospital for Sick Children
Coronary Artery Disease, Coronary Artery Bypass
Impact of Fluid Restriction Policy in Reducing the Use of Red Cells in Cardiac Surgery
The investigators' hypothesis is that restriction of circulating fluids in comparison to a liberal fluid administration policy would lead to a reduction of allogenic red blood cells exposure in patients undergoing cardiopulmonary…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Erythrocyte Transfusion
- Trial name
- NCT00600704
- Testing
- Fluid Restriction Policy, Free fluid infusion
- Where
- Greece
- Volunteers
- 192 people
- Sponsor
- Larissa University Hospital
Blood Transfusion, Cardiac Surgery
ICU Cell Saver to Reduce Blood Transfusions in Cardiac
PURPOSE: Autotransfusion devices may be employed in cardiac surgery to decrease allogenic blood requirements. Limitations of previous trials include the use of cell saver systems in selected high risk patients only or the lack of…
- Trial name
- NCT00950547
- Testing
- CARDIOPAT, Traditional Chest Drains
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Cardiochirurgia E.H.
Valvular Heart Disease
Prehabilitation and Heart Valve Surgery
To evaluate the impact of prehabilitation on quality of recovery in heart valve surgery. To evaluate the effects of Mild to moderate valvular diseases with Newyork Heart Association (NYHA) grade I and II .
- Trial name
- NCT04993963
- Testing
- Cycle Ergometery Training (Prehabilitation), Control Standard Group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Heart Defects, Congenital
Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
The staged surgical pathway to treat children with single ventricle heart defects culminates with the Fontan operation. In this procedure, systemic venous return is rerouted directly to the pulmonary arteries, which serves to…
- Trial name
- NCT00543309
- Testing
- nesiritide, milrinone
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- John M Costello
Transfusion
Use of Cell Salvage Post-operatively in Infants to Decrease Use of Allogeneic Blood Product Transfusions
Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators.
- Trial name
- cell salvage (NCT01211366)
- Testing
- Cell Saver RBCs, Conventional volume infusion
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Rochester
Cardiac Disease, Surgery
The Quality of Recovery-15 Survey After Cardiac Surgery
Patient reported outcomes are becoming increasingly recognized as an important metric to determine efficacy of interventions following recovery after cardiac surgery.
- Conditions
- Cardiac Disease, Surgery, Surgery-Complications, Cardiac Valve Disease
- Trial name
- NCT05602298
- Testing
- Quality of Recovery 15 survey
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of British Columbia
Laryngeal Injury, Swallowing Disorder
Laryngeal Disorders After Childhood Cardiac Surgery
Laryngeal disorders after childhood cardiac surgery is a complication well described in the literature. However, the long term progression of the affected children has never been studied (all the studies stopped before 2 years of…
- Conditions
- Laryngeal Injury, Swallowing Disorder, Voice Disorders in Children, Surgery--Complications
- Trial name
- RECUP-TML (NCT04638361)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Hospices Civils de Lyon
Enhanced Recovery After Surgery, Quality Improvement
Study to Evaluate the Impact of the Recovery Pathway on Postoperative Leght of Stay in Coronary Artery Bypass Surgery
This randomized and prospective trial aims to evaluate the implementation of a rapid recovery protocol for coronary artery bypass grafting (CABG) in a hospital serving patients from the Brazilian Unified Health System (Sistema…
- Trial name
- KAMAY (NCT06713096)
- Testing
- Tempos Certos protocol
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- University of Sao Paulo General Hospital
Open Heart Surgery Patients
Patient Education by Mobile Application
Cardiovascular diseases are among the important health problems that cause mortality and morbidity both in our country and in the World (Sidar vd 2013).
- Trial name
- NCT05094063
- Testing
- patient education by mobile application
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Betul Zeynep Yildiz
Infection
Salvage of Infected Cardiovascular Implantable Electronic Devices (CIED) by Localized High-dose Antibiotics
Following previous positive experience with regulated CITA-RNPT of infected CIEDs, we suggest increasing the number of recruited patients and that CITA-RNPT can be administered prophylactically to patients prior to replacement of…
- Trial name
- NCT01770067
- Testing
- CITA-RNPT, Extraction of infected CIED
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Congenital Heart Disease, Total Cavo-pulmonary Connection
Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children
Nesiritide, a recombinant human B-type natriuretic peptide, has favorable effects on patient symptoms, hemodynamics, and the neurohumoral profile in adults with decompensated congestive heart failure and in those recovering from…
- Trial name
- NCT03207295
- Testing
- Nesiritide, Normal saline
- Where
- China
- Volunteers
- 108 people
- Sponsor
- China National Center for Cardiovascular Diseases