Clinical trials: Cardiac Transplant
Heart Transplant Recipients
Autonomic Cardiovascular Control After Heart Transplantation
The purpose of this prospective study is to investigate denervation (ie. surgical cutting of autonomic nerves) and re-innervation (ie. growth of autonomic nerves) in heart transplant recipients. More specifically, we focus on: 1.
- Trial name
- AccHeart (NCT01759966)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Periodontal Diseases, Heart Transplantation
Periodontal Status and Dental Behavior of Heart Trasplant Recipients and Healthy Controls
Forty heart transplant recipients and forty age and sex mathced systemically healthy patients were included. Periodontal examination was performed and a questionnaire was applied to record demographic data, systemic health and…
- Trial name
- NCT03809676
- Testing
- periodontal examination
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
Internal Mammary Artery Syndrome, Vasodilation
Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow
Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention…
- Trial name
- NCT06301880
- Testing
- The topical application of a vasodilator on the LIMA graft
- Where
- Syria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Damascus University
Solid Organ Transplantation, Pregnancy
Long-term Follow-up of the Offspring Born to Mothers With a Solid Organ Transplant, Transplantlines Next Generation
Background Pregnancy after all types of solid organ transplantation (SOT) is possible, although these have higher risk of pregnancy complications for mother and child, such as preeclampsia and preterm birth.
- Conditions
- Solid Organ Transplantation, Pregnancy, Long-term Follow-up, Kidney Transplant
- Trial name
- NCT07291258
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Coronary Artery Disease
Decision Support Tool for Revascularisation Options in Coronary Artery Disease
Together with patients and healthcare professionals, we want to design a Decision Support Tool (DST) that will help people with coronary artery disease to understand and choose treatments that best reflect their preferences and…
- Trial name
- DECIDE-CAD (NCT06567626)
- Testing
- Decision Support Tool (DECIDE-CAD)
- Where
- 2 sites in United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Ischemic Heart Disease, Atherosclerosis
Graft Patency as a Predictor of Health-related Quality of Life.
The health-related quality of life questionnaire "EQ-5D" has been collected in connection with several interventional and observational studies where the no-touch vein harvesting technique in CABG has been used.
- Trial name
- NCT02547194
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Örebro County Council
Transplant, Heart, Magnetic Resonance Imaging
Heart Transplantation - Renewal
Heart transplantation (HTx) is a well-established life-saving procedure but is associated with severe complications. Regular monitoring of heart transplant recipients is thus important for the early detection of these…
- Trial name
- HeartRenewal (NCT05521399)
- Testing
- MRI Sequencing, MRI Testing (pediatric), MRI Testing
- Where
- 2 sites in United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Angina, Coronary Artery Disease
Exercise-training Before Coronary Artery Bypass Graft (CABG)
The aim is to evaluate the effect of exercise training upon endothelial function in the mammary artery of patients who are scheduled for CABG, as well as study the functional properties of single cells isolated from a small…
- Trial name
- NCT00218985
- Testing
- Exercise training
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cardiac Transplant Failure, Cardiac Transplant Rejection
Outcomes AlloMap Registry: the Long-term Management and Outcomes of Heart Transplant Recipients With AlloMap Testing
The objective of this registry is to observe short and long term clinical outcomes in heart transplant recipients who receive regular AlloMap testing as part of allograft rejection surveillance.
- Conditions
- Cardiac Transplant Failure, Cardiac Transplant Rejection, Heart Diseases
- Trial name
- OAR (NCT01833195)
- Where
- 36 sites in United States
- Volunteers
- 2,444 people, healthy volunteers welcome
- Sponsor
- CareDx
Coronary Artery Bypass Grafting, Preoperative Anxiety
Nurse Navigation Programs Affect to Anxiety, Perception of Quality Nursing Care and Stress Hormone Levels
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery…
- Trial name
- NCT07528989
- Testing
- Nursing navigation program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
Cardiac, Surgery (Cardiac)
AI-Generated Video Feedback to Improve Technical Skills in Coronary Artery Bypass Grafting
This study aims to evaluate whether targeted video feedback generated by an artificial intelligence (AI)-based surgical performance assessment model can support improvement in technical skills among cardiac surgeons performing…
- Conditions
- Cardiac, Surgery (Cardiac), Education, Artificial Intelligence (AI)
- Trial name
- NCT07400172
- Testing
- AI-Guided Video Feedback Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Arteriosclerosis of Arterial Coronary Artery Bypass Graft
Long Term Follow-up of Open Versus Endoscopic Radial Artery Harvest With CT Angiography
The objectives of the study are two-fold: 1. To determine the mean 5 year patency rate of the radial artery graft (Open vs. Endoscopic) of patients who have already had CABG surgery and who previously participated in the centre's…
- Trial name
- NCT01559376
- Where
- 2 sites in Canada
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Orthotopic Heart Transplant
Motivational Interviewing and Group Heart Transplant Exercise and Education: A Pilot Study
The aim of this 16-week group aerobic training program, delivered remotely via video-conferencing, is to assess program feasibility, and determine if program increases physical activity in adolescents after heart transplant.
- Trial name
- MIGHTEE (NCT05398744)
- Testing
- Group Exercise Program
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Transplant Failure, Cardiac Transplant Rejection
Utility of Donor-Derived Cell Free DNA in Association With Gene Expression Profiling
Plasma donor-derived cell-free DNA (dd-cfDNA) is measured as a % of the total plasma cfDNA in association with the measurement of AlloMap, a non-invasive gene expression test to aid in heart transplant management.
- Conditions
- Cardiac Transplant Failure, Cardiac Transplant Rejection, Heart Diseases
- Trial name
- D-OAR (NCT02178943)
- Where
- 28 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- CareDx
Chest Pain, Coronary Occlusion
Advanced Cardiovascular Imaging Consortium
The ACIC is a Collaborative Quality Improvement (CQI) program involving the collection of data related to: indications for Coronary Computed Tomography (CCTA), patient health characteristics, acquisition techniques of CCTA scans…
- Conditions
- Chest Pain, Coronary Occlusion, Coronary Artery Disease
- Trial name
- ACIC (NCT00640068)
- Where
- 50 sites in United States
- Volunteers
- 42,926 people, healthy volunteers welcome
- Sponsor
- Corewell Health East