Clinical trials: CardioPulmonary Resuscitation
Out-of-hospital Cardiac Arrest
The PulsePoint Randomized Controlled Trial
"Sudden cardiac arrest" occurs when someone's heart stops beating unexpectedly. Each year, more than 45,000 Canadians have a cardiac arrest.
- Trial name
- NCT01746290
- Testing
- PulsePoint notification
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Airway Aspiration, Cardiopulmonary Arrest
The Impact of Soiled Airway Management on CPR Quality
Regurgitation is an adverse event common during cardiopulmonary resuscitation (CPR) and occurs in 20%-32% of patients experiencing out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT05278923
- Testing
- SALAD simulation device
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Heart Arrest, Ventricular Fibrillation
AED Use in Out-of-Hospital Cardiac Arrest: A New Algorithm Named "One Shock Per Minute"
The aim of the trial is to evaluate a new AED algorithm that proposes a new timeline between the time devoted to administer a defibrillation shock, and the time devoted to chest compressions.
- Trial name
- DEFI2005 (NCT00139542)
- Testing
- One shock per minute AED protocol, Guidelines 2000 AED protocol
- Where
- France
- Volunteers
- 5,107 people
- Sponsor
- Fire Brigade Of Paris Emergency Medicine Dept
Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation
Cross-sectional Survey of Zhejiang ECMO Application
Extracorporeal lung oxygenation (ECMO) was first used in neonates in the 1970s and is now widely used to treat adult patients with intractable shock and respiratory failure who have failed various types of conventional life…
- Conditions
- Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation, Epidemiology
- Trial name
- NCT04979325
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Heart Arrest, Birth Asphyxia
SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Research question In newborn infants requiring CPR, does CC superimposed by sustained inflation compared to 3:1 compression to ventilation ratio improves return of spontaneous circulation? Overall objective: CC superimposed by…
- Conditions
- Heart Arrest, Birth Asphyxia, Bradycardia
- Trial name
- SURV1VE (NCT02858583)
- Testing
- CC+SI, 3:1 C:V
- Where
- 4 sites in Austria, Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Cardiac Arrest
Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT01806844
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
End of Life
Survey on Palliative Care and Law Perception
The primary objective of the current survey study is to obtain detailed information about European intensive care unit (ICU) clinicians' awareness of palliative care and relevant, local end-of-life (EoL) legislation.
- Trial name
- PCLAW (NCT06245525)
- Testing
- This is not an interventional study
- Where
- Greece
- Volunteers
- 523 people
- Sponsor
- University of Athens
Heart Arrest, Seizures
Prompt Diagnosis and Treatment of Subclinical Seizures After Cardiac Arrest
Non-convulsive seizures (NCS) following cardiac arrest are common and are associated with worse neurologic outcomes and increased mortality. More prolonged seizures (status epilepticus) are associated with worse outcomes.
- Trial name
- NCT02458820
- Testing
- DSA EEG
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
Intraoperative Cardiac Arrest
Cardiopulmonary Resuscitation in Operating Room
In the last ten years patient safety during routine surgical interventions has increased; however as there is an increase in the number of specialized surgical interventions and high risk patients like elderly and emergency…
- Trial name
- CPR (NCT02884271)
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Dokuz Eylul University
Cardiac Arrest, Sudden, Ventricular Tachycardia
Cardiopulmonary Resuscitation Performance of Professional Rescuers With a New Defibrillation Algorithm
In the Paris (France) Medical Emergency system, in the early phase of Out-of-hospital Cardiac Arrest (OHCA), the treatment of a Ventricular Fibrillation (VF) consists of delivering an External Electric Shock (EES) by a rescuer…
- Conditions
- Cardiac Arrest, Sudden, Ventricular Tachycardia, Ventricular Fibrillation, Sudden Cardiac Death
- Trial name
- DEFI-2022 (NCT04691089)
- Where
- France
- Volunteers
- 285 people
- Sponsor
- French Defence Health Service
Heart Arrest, Heart Arrest, Out-Of-Hospital
An Educational Program to Improve Cardiac Arrest Diagnostic Accuracy of Ambulance Telecommunicators
Cardiac arrest is the number one cause of death in Canada. It is often the first symptom of cardiac disease for the victims. Eighty-five percent of victims collapse in their own home.
- Conditions
- Heart Arrest, Heart Arrest, Out-Of-Hospital, Cardiac Arrest, Death, Sudden, Cardiac
- Trial name
- NCT03894059
- Testing
- Educational Intervention
- Where
- Canada
- Volunteers
- 12,224 people
- Sponsor
- Ottawa Hospital Research Institute
Out-Of-Hospital Cardiac Arrest, Emotional Distress
Does Bystanders Emotional State Influence Dispatcher-assisted Cardiopulmonary?Resuscitation
The study aims to investigate bystanders' emotional stress state in out-of-hospital cardiac arrest (OHCA) emergency calls and the association with the quality of dispatcher-assisted cardiopulmonary resuscitation (DA-CPR).
- Trial name
- NCT05113706
- Where
- Denmark
- Volunteers
- 1,100 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Cardiopulmonary Resuscitation
Optimization of Quality in Cardiopulmonary Resuscitation Through Monitor-defibrillator With Feedback System
AIM: To verify the effect of a feedback system on optimizing quality during CPR on mannequins. Hypothesis: The quality of CPR performed by healthcare professionals through a defibrillator monitor with a feedback system is higher…
- Trial name
- NCT04357548
- Testing
- FEEDBACK
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Outcome From Traumatic Cardiac Arrest
This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest.
- Trial name
- NCT05294575
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Pediatric ALL, Cardiac Arrest
Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA
Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest.
- Conditions
- Pediatric ALL, Cardiac Arrest, Cardiopulmonary Arrest, Resuscitation
- Trial name
- NCT05498402
- Testing
- i-gel ® device, bag-valve-mask ventilation
- Where
- 4 sites in Switzerland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
out-of Hospital Cardiac Arrest
Pre-Hospital Cerebral Oxygenation and End-Tidal CO2 During Cardiopulmonary Resuscitation (CPR)
Cerebral saturation will be measured pre-hospital during an out-of hospital cardiac arrest with O3TM regional oximetry for Root® (Masimo®).
- Trial name
- CopernicusIb (NCT02850237)
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Pulmonary Hypertension, Bronchopulmonary Dysplasia
Study of the Effect of Four Methods of Cardiopulmonary Resuscitation Instruction on Psychosocial Response of Parents With Infants at Risk of Sudden Death
OBJECTIVES: I. Describe the psychosocial response of parents and caretakers who learn cardiopulmonary resuscitation (CPR) techniques for infants at high risk for respiratory or cardiac arrest. II.
- Conditions
- Pulmonary Hypertension, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome
- Trial name
- NCT00004805
- Testing
- CPR instruction
- Volunteers
- 500 people
- Sponsor
- National Center for Research Resources (NCRR)
Cardiopulmonary Resuscitation
Optimizing Integration of CPR Feedback Technology With CPR Coaching for Cardiac Arrest
There is significant data showing that the quality of CPR performed is quite poor. Recent studies have shown that when real-time visual corrective feedback is available to CPR providers, quality (compression depth and rate)…
- Trial name
- NCT03204162
- Testing
- CPR Coaching
- Where
- 5 sites in United States, Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Cardiac Arrest
Comparison of Chest Compressions Performed With the Lower Limb and the Classical Method (Lower_limb_CPR).
Chest compressions, alongside early defibrillation, are the most important component of basic life support for adults. High-quality compressions give the patient a chance to survive cardiac arrest.
- Trial name
- Lower_limb_CPR (NCT07646496)
- Testing
- Instruction to perform chest compressions using the lower limb (foot)
- Where
- Poland
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Marcin Muża
Cardiac Arrest, Cardiopulmonary Arrest
Continuous Compressions With Asynchronous Ventilations Using I-gel Device Versus 30:2 Approach During Simulated OHCA
Paramedics and EMT will be recruited among four Emergency Medical Services (EMS) in Switzerland to manage a 10-minutes simulation-based adult out-of-hospital cardiac arrest scenario in teams of two.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Emergency Medical Services, Resuscitation
- Trial name
- NCT04736446
- Testing
- I-gel® supraglottic device, Face mask ventilation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances