Clinical trials: Cardiometabolic Health
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Dysbiosis, Cardiometabolic Health Indicators
Pulse Education and Children
This parallel-arm, randomized controlled trial will evaluate the effectiveness of a 6-week pulse-focused nutrition intervention in school-aged children (6-13 years).
- Conditions
- Dysbiosis, Cardiometabolic Health Indicators, Education on Feeding and Health Status, Gut Motility
- Trial name
- NCT07648446
- Testing
- Education Only, Education + Pulse Provision, Cooking Class
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
In Utero Drug Exposure
Cardiometabolic Health of Children Exposed to Anti-retroviral Therapy (ART) in Utero
The Human Immunodeficiency Virus (HIV) has been recently linked to increased risk for cardiovascular diseases (CVDs). The prevalence of cardiovascular diseases and its risk factor, hypertension, are very high in African…
- Trial name
- ARTMOMSBABES (NCT04763668)
- Testing
- Pregnant HIV positive women on ARTs, Babies born to HIV positive mothers on ARTs
- Where
- South Africa
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Walter Sisulu University
Sleep, Body Composition
Nutrition, Body Composition, and Sleep
The purpose of the research is to determine if protein and omega-3 fatty acid supplementation improve sleep, improve body composition, and improve markers of metabolic health in postmenopausal women.
- Conditions
- Sleep, Body Composition, Strength, Insulin Sensitivity
- Trial name
- SHAPE (NCT03603041)
- Testing
- Whey protein, Omega-3 fatty acids
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
Adiposity, Insulin Sensitivity
The Sweet Kids Study (Stevia on Weight and Energy Effect Over Time)
This is an 8 to14-week three-arm randomized controlled in children 8 to 12 years old. The main purpose of the study is to evaluate if stevia has benefits for weight control and metabolic function relative to caloric sweeteners…
- Conditions
- Adiposity, Insulin Sensitivity, Weight Gain, Blood Pressure
- Trial name
- NCT05992688
- Testing
- Sucrose sweetened beverage, Stevia sweetened beverages, Calorie free flavored water beverage
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Bone Health, Muscle Function
Effects of Milk Protein and Vitamin D on Children's Growth and Health
The purpose of D-pro is to investigate the combined and separate effects of milk protein and vitamin D on bone health, growth, muscle function, body composition and cardiometabolic health in 6-8-year-old children.
- Conditions
- Bone Health, Muscle Function, Cardiometabolic Health, Appetite Regulation
- Trial name
- D-pro (NCT03956732)
- Testing
- Milk Protein (high), Vitamin D, Milk Protein (medium)
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cardiometabolic Health Indicators, Whole-body Antioxidant Capacity
Effect of Watermelon on Cardiometabolic Health
The purpose of this study is to determine whether consumption of 355 ml of watermelon juice will: 1. improve cardiovascular and overall metabolic health markers like blood pressure, heart rate, stiffness/flexibility of arteries…
- Trial name
- NCT07006636
- Testing
- Watermelon Juice + liquid meal test at baseline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Vitamin D Deficiency
The Effect of Vitamin D Supplements on Vitamin D Status, Cardiometabolic Health and Immune Defense in Danish Children
The main purpose of this study is to investigate whether and in which doses vitamin D intake is needed in order to maintain an adequate vitamin D status in 4-8 year-old Danish children during wintertime.
- Trial name
- ODIN Junior (NCT02145195)
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Dysbiosis, Cardiometabolic Health Indicators
Almonds, Gut Microbiome and Kids
This 8-week parallel-arm randomized controlled trial (N=70; ages 6-13) will determine the impact of daily almond butter consumption on gut microbiome composition and function, intestinal barrier integrity, and cardiometabolic…
- Trial name
- NCT07636850
- Testing
- Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Florida State University
Transgender, Transgenderism
Cardiometabolic Health in Transgender Males
Transgender individuals are those with a gender identity opposite the sex they were assigned at birth. Approximately 1% of the population is transgender, equating to ~60,000 transgender Wisconsinites.
- Trial name
- NCT04977765
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Cardiometabolic Health, Cognitive Function
The Effect of Oily Fish and Poultry on Children's Cardiometabolic Health and Cognitive Function
The purpose of FiSK Junior is to investigate whether intake of oily fish compared to poultry affects cardiovascular risk markers, cognitive function, and behaviour in healthy children.
- Trial name
- FiSK Junior (NCT02809508)
- Testing
- Oily fish, Poultry
- Where
- Denmark
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Health Behavior
An Integrated Closed-loop Feedback System for Pediatric Cardiometabolic Disease
The high prevalence and burden of cardiometabolic disease underlie the urgent need to identify novel approaches to managing and preventing cardiometabolic disease and risk.
- Trial name
- STRIVE (NCT02659163)
- Testing
- mHealth wristband, mHealth scale, EMA
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diet, Food, and Nutrition, Exercise
The NutriNet-Santé Study
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between…
- Conditions
- Diet, Food, and Nutrition, Exercise, Diseases Category, Cohort Studies
- Trial name
- NCT03335644
- Where
- France
- Volunteers
- 170,000 people, healthy volunteers welcome
- Sponsor
- University of Paris 13
Sedentary Behavior, Physical Activity
MOVI-OLE! [Open Learning Environments]
This study will evaluate the effectiveness of MOVI-OLE! (Open Learning Environment), a school-based intervention designed to reduce sedentary time and enhance multiple aspects of child development, including cognitive function…
- Conditions
- Sedentary Behavior, Physical Activity, Cognitive Function, Mental Health
- Trial name
- MOVI-OLE! (NCT07103343)
- Testing
- MOVI-OLE intervention
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Focus of Study: Work Conditions
Evaluating the Health Benefits of Workplace Policies and Practices - Phase II
Although the prevalence of "family-friendly" policies in US workplaces has increased dramatically, few have been studied using scientifically sound designs.
- Trial name
- WFHS (NCT02050204)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 2,753 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Vitamin D Deficiency
Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]
The purpose of this research is to determine what supplemental doses of vitamin D may be necessary to raise serum levels to optimal levels and how vitamin D supplementation and changes in vitamin D status impact cardiovascular…
- Trial name
- NCT01537809
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 691 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers
Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents
Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as…
- Conditions
- Cardiometabolic Health Indicators, Vascular Function in Healthy Volunteers, Inflammation
- Trial name
- NCT07125001
- Testing
- Ataulfo mango
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cardiometabolic Health Indicators, Child Health
Non-Invasive Assessment of Early Health Determinants in Children and Adolescents
LONGEVITY-NEXT is a single-center, non-profit observational study designed to assess early non-invasive determinants of cardiometabolic, functional, behavioral, and environmental health in children and adolescents aged 6 to 17…
- Trial name
- LONGEVITY-NEXT (NCT07861516)
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Adolescent Behavior
H2 Physical Education: Promoting Cardiometabolic Health by 2 High Intensity Intervallic Training Protocol, Twice a Week at Physical Education
Several risk factors associated with cardiovascular disease could be prevented or treated by means of physical activity from childhood.
- Trial name
- H2PE (NCT05544370)
- Testing
- Intensive high intensity intervallic training group, Extensive high-intensity intervallic training
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Polycystic Ovary Syndrome, Exercise
The Effects of High-intensity and Moderate-intensity Exercise on Polycystic Ovary Syndrome
This study will investigate the impact of high- and moderate-intensity exercise on the cardiometabolic and brain health of women with Polycystic Ovary syndrome (PCOS).
- Conditions
- Polycystic Ovary Syndrome, Exercise, Cerebrovascular Circulation
- Trial name
- NCT05394935
- Testing
- High-Intensity Exercise, Moderate-Intensity Exercise
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cardiff Metropolitan University