Clinical trials: Cardiomyopathy, Congestive
DCM - Dilated Cardiomyopathy
Observational Study for Patients With Dilated Cardiomyopathy
Observational study on patients with dilated cardiomyopathy aims to investigate the correlation between cardiac fibrosis, as indicated by cardiac magnetic resonance, and the prognosis of patients with dilated cardiomyopathy, and…
- Trial name
- NCT04837612
- Testing
- No intervention nor exposure
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Guangdong Provincial People's Hospital
Dilated Cardiomyopathy
Pathophysiology of Dilated Cardiomyopathy
This will be a cross-sectional, observational study. Null hypothesis: There is no difference in the amount of extracellular volume (ECV or scarring) in the hearts of patients with heart failure as compared to control subjects.
- Trial name
- NCT02001961
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Dilated Cardiomyopathy
A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM)
This is a Phase 1 study to determine the safety and efficacy of allogeneic neonatal mesenchymal stromal cells (nMSCs) for the treatment of Dilated Cardiomyopathy.
- Trial name
- NCT06464588
- Testing
- Allogeneic Neonatal mesenchymal stromal cells (nMSCs)
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Emory University
Dilated Cardiomyopathy, Pediatric
Resynchronization Therapy in Young Patients With and Without CHD
Pacemakers can be attached to one or more than one of the heart chambers. After watching pacemakers work over time, doctors have found that the pacemakers that stimulate only one chamber of the heart sometimes lead to problems…
- Trial name
- NCT00208806
- Testing
- congestive heart failure patients
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Cardiomyopathy
New Horizons for the Treatment of Cardiomyopathy in Children
Collecting mono nuclear cells from the patient's blood after a course of granulocyte stimulation then injecting them into the weak heart muscle measuring the heart function at the beginning and after 2.4.6 months to assess the…
- Trial name
- NCT04893629
- Testing
- mono nuclear cells injection, Digoxin+furosemide+captopril
- Where
- Syria
- Volunteers
- 22 people
- Sponsor
- Damascus University
Lamin A/C Gene Mutation, Dilated Cardiomyopathy, Familial
The Deep Phenotype of Lamin A/C Cardiomyopathy
This study seeks to discover clinically useful tests to improve the diagnosis of a rare and serious heart muscle disease caused by mutations in a gene called 'Lamin'.
- Trial name
- NCT03860454
- Where
- 6 sites in United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University College, London
Duchenne Muscular Dystrophy, Duchenne Muscular Dystrophy-Associated Dilated Cardiomyopathy
Duchenne Muscular Dystrophy Heart Study
Retrospective cohort study including patients with genetically proven Duchenne muscular dystrophy, diagnosed from January 1993 to March 2020.
- Trial name
- DMD-HS (NCT03443115)
- Where
- France
- Volunteers
- 700 people
- Sponsor
- Hôpital Cochin
Zinc Deficiency
Zinc Deficiency in Dilated Cardiomyopathy
The aim of this study is to detect effect of oral zinc supplementation in pediatric patients with dilated cardiomyopathy.
- Trial name
- NCT04860921
- Volunteers
- 50 people
- Sponsor
- Assiut University
Heart Failure, Dilated Cardiomyopathy
Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated Cardiomyopathy
Paediatric clinical trial in 50 children, from 1 month to less than 12 years of age, suffering from heart failure due to dilated cardiomyopathy, to obtain paediatric pharmacokinetic and pharmacodynamic data of enalapril and its…
- Trial name
- LENA-WP08 (NCT02652728)
- Testing
- Enalapril Orodispersible Minitablet
- Where
- 6 sites in Austria, Hungary and 3 more
- Volunteers
- 50 people
- Sponsor
- Ethicare GmbH
Dilated Cardiomyopathy
Clinical and Genetic Examinations of Dilated Cardiomyopathy
This study is a descriptive study to investigate clinical and genetic features of dilated cardiomyopathy (DCM) patients and their relatives.
- Trial name
- NCT02148926
- Where
- Denmark
- Volunteers
- 554 people
- Sponsor
- University of Southern Denmark
Heart Failure, Congestive, Ventricular Dysfunction
Thoratec HeartMate II Left Ventricular Assist System (LVAS) for Bridge to Cardiac Transplantation
The purpose of this study is to determine the safety and effectiveness of the Thoratec HeartMate II Left Ventricular Assist System (LVAS) as a bridge to cardiac transplantation in end-stage heart failure patients who are listed…
- Conditions
- Heart Failure, Congestive, Ventricular Dysfunction, Cardiomyopathies
- Trial name
- NCT00121472
- Testing
- Thoratec HeartMate II Left Ventricular Assist System (LVAS)
- Where
- 36 sites in United States, Canada
- Volunteers
- 194 people
- Sponsor
- Abbott Medical Devices
Pediatric Dilated Cardiomyopathy
Potential Role of Water-soluble Ubiquinol in Complementary Therapy for Pediatric Dilated Cardiomyopathy
Pediatric dilated cardiomyopathy (PDCM) is the most common form fond in children. Water-soluble coenzyme Q10 (ubiquinol) is better absorbed than lipid-soluble coenzyme Q10 (ubiquinone) and is directly involved in the antioxidant…
- Trial name
- NCT02847585
- Testing
- Water-soluble Ubiquinol
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chung Shan Medical University
Muscular Dystrophy, Dilated Cardiomyopathy
The Cardiovascular Genetic and Therapeutic Implications of Muscular Dystrophy
This study will have significant impact on muscular dystrophy patients as it promotes early screening for heart disease. With early identification, beneficial medical therapy can be started sooner, resulting in restoring and…
- Conditions
- Muscular Dystrophy, Dilated Cardiomyopathy, Heart Failure
- Trial name
- NCT00518817
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy
The Genetics of Cardiomyopathy and Heart Failure
The purpose of this study is to determine the genetic basis of cardiomyopathies and heart failure.
- Conditions
- Dilated Cardiomyopathy, Hypertrophic Cardiomyopathy, Mitochondrial Cardiomyopathy, Noncompaction Cardiomyopathy
- Trial name
- NCT00703443
- Where
- United States
- Sponsor
- University of California, Irvine
Acute Heart Failure, Dilated Cardiomyopathy
Early Administration of Ivabradine in Children With Heart Failure
This is a monocentric, prospective, single arm, not for profit study. It is designed to study the early use of ivabradine in patients with dilated cardiomyopathy and Ejection Fraction (EF) < 45%.
- Trial name
- EASI-Child (NCT04405804)
- Testing
- Ivabradine 5Mg Tab
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Long QT Syndrome, Brugada Syndrome
Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations
The QUALIMYORYTHM trial is a multicentre controlled study, aiming to assess health-related quality of life (HRQoL) of 107 children aged 6 to 18 years old with inherited cardiac arrhythmia (long QT syndrome, Brugada syndrome…
- Conditions
- Long QT Syndrome, Brugada Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Arrhythmogenic Right Ventricular Dysplasia
- Trial name
- QUALIMYORYTHM (NCT04712136)
- Testing
- MRI
- Where
- France
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Heart Failure
the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients
the study to investigate the efficacy of empagiflozin in pediatric heart failure
- Trial name
- NCT07692256
- Testing
- Empagliflozin (EMPA), Standard medical treatment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Idiopathic Dilated Cardiomyopathy
Honey in Idiopathic Dilated Cardiomyopathy
Background: Honey, as a natural product produced by honey bees, has anti-oxidant, anti-microbial, anti-inflammatory and immunomodulator properties.
- Trial name
- NCT02987322
- Testing
- honey
- Volunteers
- 50 people
- Sponsor
- mamdouh abdulmaksoud abdulrhman
Long QT Syndrome, Brugada Syndrome
Physical Activity in Children With Inherited Cardiac Diseases
Use lay language. Current guidelines regarding physical activity in patients with inherited arrhythmia and cardiomyopathy are mostly dedicated to adult patients, with a special focus on sports competition.
- Conditions
- Long QT Syndrome, Brugada Syndrome, Catecholaminergic Polymorphic Ventricular Tachycardia, Hypertrophic Cardiomyopathy
- Trial name
- NCT04650009
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Montpellier
Cardiovascular Diseases, Heart Diseases
Epidemiology of Idiopathic Dilated Cardiomyopathy (Washington, DC Dilated Cardiomyopathy Study)
To identify risk factors for idiopathic dilated cardiomyopathy and to examine prognostic factors over a follow-up period of two to three years.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Diseases, Asthma
- Trial name
- NCT00005262
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)