Clinical trials: Cardiovascular Outcomes
Heart Failure
"A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
This is a pilot randomized clinical trial that have employed a motivational interviewing intervention to enhance self-care in heart failure patients.
- Trial name
- MITI (NCT07721909)
- Testing
- Motivational interviewing, Standard Care (Treatment as Usual)
- Where
- Oman
- Volunteers
- 60 people
- Sponsor
- Sultan Qaboos University
Low Flow Anesthesia, High Flow Anesthesia
Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels and Postoperative Patient Outcomes in Pediatric Cardiovascular Surgery
Low flow anesthesia; It is an anesthesia practice in which, after absorbing at least 50% of the exhaled air and carbon dioxide (CO2) using a semi-closed rebreathing system, the unused anesthetic gases are mixed with a certain…
- Trial name
- NCT06097806
- Testing
- low and high flow
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
ST Elevation Myocardial Infarction
Impact of Glycemic State on Patients ST Elevation Myocardial Infarction With Primary Percutaneous Coronary Angioplasty
ST-elevation myocardial infarction is a major cause of morbidity and mortality worldwide. ST-elevation myocardial infarction damages the regional myocardium that undergoes ischemia and necrosis, resulting in impairment of both…
- Trial name
- NCT03266978
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Cardiomyopathy, Hypertrophic
The Chinese Hypertrophic Cardiomyopathy Study(CHCS)
Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiac diseases, with a prevalence of ∼0.2%. Sudden cardiac death (SCD), heart failure and stroke are the major poor outcomes of HCM.
- Trial name
- CHCS (NCT02696135)
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- China National Center for Cardiovascular Diseases
Congenital Heart Defect
Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology
A randomized, blinded, controlled trial to evaluate growth velocity and clinical outcomes in infants with single ventricle physiology fed an exclusive human milk diet prior to, and throughout the post-operative period following…
- Trial name
- NCT02860702
- Testing
- Human Milk Derived Fortifier, Human/Bovine Milk
- Where
- 12 sites in United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Stroke
Clinical Charactaristics , Risk Factors and Outcomes of Stroke in Pediatric Patients at Assiut University Children's Hospital
Summary of the study is to recognize clinical picture , to identify risk factors and evaluate outcomes of stroke in pediatric patients
- Trial name
- NCT07120568
- Volunteers
- 45 people
- Sponsor
- Assiut University
Congenital Heart Disease
Procedural Outcomes of Percutaneous PDA Closure: Comparative Study Between Different Devices.
To compare safety, efficacy and procedural outcome of percutaneous PDA closure using different approaches for better characterization of device selection criteria.
- Trial name
- NCT04303793
- Testing
- Percutaneous PDA closure
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Ischemia, Phantom Limb Pain
Sciatic Perineural Versus Stump Catheter for Below Knee Amputation
The goal of this study is to determine if pre-operative placement of the continuous peripheral nerve block by an anesthesiologist using ultrasound technology is more effective than a continuous peripheral nerve block placed…
- Conditions
- Ischemia, Phantom Limb Pain, Vascular Disease, Chronic Pain
- Trial name
- NCT01608035
- Testing
- Sciatic catheter, Stump catheter
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- University of British Columbia
Cardiology, Nefrology
Telerehabilitation in Hemodialysis Patients.
Chronic kidney disease is the third most common cause of death, with a prevalence of 10-12%. Patients undergoing hemodialysis often exhibit low levels of physical activity, leading to various health issues, including poor quality…
- Trial name
- Teledialysis (NCT06891482)
- Testing
- Telerehabilitation
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Hartcentrum Hasselt
Coronary Artery Disease
Clinical and Procedural Outcomes of Ostial Left Anterior Descending Artery Intervention With or Without Crossover to Left-main
Prospective interventional study evaluating clinical and procedural outcomes of patients with ostial left anterior descending artery lesion PCI alone or crossover with left main artery
- Trial name
- NCT05933473
- Testing
- Percutaneous coronary intervention
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
Transposition of Great Vessels, Outcome, Fatal
Outcomes of Transposition of the Great Arteries After Arterial Switch Operation
Transposition of the great arteries (TGA) is a complex cyanotic congenital heart disease and patients suffer from a high mortality rate within one year of age without appropriate management.
- Trial name
- NCT05089773
- Testing
- The arterial switch operation
- Where
- 2 sites in China
- Volunteers
- 1,281 people
- Sponsor
- Children's Hospital of Fudan University
Infant,Premature
Prematurity Related Ventilatory Control (PRE-VENT) - Specific Aim 2
To determine if late (at or beyond postnatal day 14) mild permissive hypercapnia is associated with reduction in apnea, bradycardia, and hypoxemic episodes and with improved stability of oxygenation.
- Trial name
- NCT03333161
- Testing
- Cardiorespiratory monitoring
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Alpha-Thalassemia, Beta-Thalassemia
FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
FLOWER is a completely virtual, nationwide, real-world observational study to collect, annotate, standardize, and report clinical data for rare diseases.
- Conditions
- Alpha-Thalassemia, Beta-Thalassemia, Amyloidosis, Amyotrophic Lateral Sclerosis
- Trial name
- NCT06539169
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- xCures
Chronic Disease, HIV/AIDS
Observational Pharmaco-Epidemiology Research & Analysis
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management…
- Conditions
- Chronic Disease, HIV/AIDS, Liver Diseases, Inflammatory Bowel Diseases
- Trial name
- OPERA (NCT03813862)
- Testing
- Non-interventional (observational only)
- Where
- United States
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Epividian
Cardiac Arrest (CA), Pediatric ALL
Dutch Registry of Pediatric Cardiac Arrest
The goal of this observational study is to understand the long-term outcomes of children in the Netherlands who experience cardiac arrest, either in or outside of the hospital.
- Trial name
- PROGNOSE (NCT06938009)
- Where
- 7 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- Matthijs de Hoog
Congenital Heart Disease, Oral Aversion
Nasal vs. Oral Intubation for Neonates Requiring Cardiac Surgery
Often, infants struggle to feed orally after surgery for congenital heart disease and may require supplemental feeding interventions at discharge.
- Trial name
- NCT05378685
- Testing
- Endotracheal intubation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Virginia
Acute Coronary Syndromes, Coronary Artery Disease
Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes
This is a multi-centre UK study designed to evaluate if an educational intervention programme delivered to health care professionals can improve the use of evidence based treatments in the management of patients admitted to…
- Trial name
- NCT00716352
- Testing
- Educational intervention programme
- Where
- 37 sites in United Kingdom
- Volunteers
- 1,340 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Liver Cirrhosis, Venous Thromboembolism
Risk Factors and Outcomes of Acute Venous Thromboembolism in Cirrhotic
patient with liver cirrhosis was supposed to have autoanticoagulation which approved to be wrong, with absence of conventional method to detect all abnormalities in coagulation state.
- Trial name
- NCT03580577
- Testing
- thromboelastography
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gait, Hemiplegic, Quality of Life
Effect of Using a Lower Limb Robotic Device for Patients With Chronic Stroke
This study will investigate if a lower limb robotic device can be used in a community setting to increase the amount of physical activity that individuals undertake following stroke and consequently improve biomechanical…
- Conditions
- Gait, Hemiplegic, Quality of Life, Vascular Stiffness, Stroke
- Trial name
- NCT03104127
- Testing
- Alter G Bionic Leg, Normal therapy (physiotherapy)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Winchester