Clinical trials: Caries Arrested
Early Childhood Caries
Silver Diamine Fluoride(SDF) Versus SDF Combined With Sodium Fluoride Varnish in the Arrest of Early Childhood Caries
Early childhood caries (ECC) is the most common chronic childhood disease worldwide. Early restorative intervention may treat the disease but this is often difficult especially with uncooperative children so it may be left…
- Trial name
- NCT05642494
- Testing
- SDF, NaF
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Alexandria University
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Dental Caries
Comparing Two Brands of Silver Diamine Fluoride for Stopping Cavities in Children
this study aims to evaluate two different materials used to stop dental caries in children. both materials are available at the market. both materials leave black stain after application.
- Trial name
- SDF (NCT07708883)
- Testing
- SDF, ToothMate®, Egypt, SDF, Advantage Arrest USA
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- National Research Centre, Egypt
Dental Health, Caries
Efficacy of Proximal Caries Infiltration
The goal of the project is to investigate the clinical efficacy of management of early caries lesions by resin infiltration and to further scrutinize the patient stress experiences.
- Trial name
- NCT01726179
- Testing
- Resin infiltration, Control
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- DMG Dental Material Gesellschaft mbH
Primary Teeth, Microbial Colonization
The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth
To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).
- Conditions
- Primary Teeth, Microbial Colonization, Caries, Dental Caries in Children
- Trial name
- NCT05221749
- Testing
- Nanosilver Fluoride (NSF), Silver diamine fluoride
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nour Ammar, BDS
Dental Caries
Pharmacokinetics of Advantage Arrest in Children
The purpose of this study is to characterize basic PK parameters (Cmax, t1/2, AUC) in healthy children to contribute to evidence for the safety of Advantage Arrest, consistent with Guidance for Industry--Exposure--Response…
- Trial name
- NCT04186663
- Testing
- Silver Diamine Fluoride
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Caries Arrested
Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride Solution
This study was conducted to assess the efficacy of 38% Silver Diamine fluoride and compare it with 5% sodium fluoride varnish in arresting interproximal caries in primary molars at 12 months follow-up.
- Trial name
- NCT05791669
- Testing
- Silver diamine fluoride, Sodium fluoride varnish
- Where
- India
- Volunteers
- 45 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Dentine Caries
Effectiveness of Single and Dual Silver Fluoride Application
This is a community-based, parallel-group, double-blinded randomised controlled trial aimed at evaluating the effectiveness of single and dual applications of 38% Silver Fluoride (SF) in arresting dentinal caries among Malaysian…
- Trial name
- NCT07658690
- Testing
- 38% Silver Fluoride (Riva Star Aqua)
- Where
- Malaysia
- Volunteers
- 148 people
- Sponsor
- University of Malaya
Early Childhood Caries
Arresting Early Childhood Caries With a Silver Diamine Fluoride Gel
The objective is to determine whether the efficacy of a 38% silver diamine fluoride (SDF) gel is non-inferior to a 38% SDF solution for arresting carious lesions in preschool children when applied at half-yearly intervals over a…
- Trial name
- NCT06241261
- Testing
- Silver diamine fluoride gel, Silver diamine fluoride solution
- Where
- China
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Dental Caries in Children, Satisfaction
Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress.
- Conditions
- Dental Caries in Children, Satisfaction, Cost Effectiveness, Oral Health
- Trial name
- NCT03480516
- Testing
- SDF, Fluoride varnish
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Caries Arrested
Clinical and Laboratory Assessments of Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Caries Among Children and Parental Satisfaction
Globally, it is estimated that 2.4 billion people suffer from caries of permanent teeth and 486 million children suffer from caries of primary teeth .
- Trial name
- NCT04642846
- Testing
- Silver Diamine Fluoride (SDF)
- Where
- Saudi Arabia
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Khalood Saeed Bahammam
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba
White Spot Lesions, Orthodontic Appliance Complication
Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment
Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances.
- Conditions
- White Spot Lesions, Orthodontic Appliance Complication, Caries Arrested, Smooth Surface Caries
- Trial name
- NCT05733676
- Testing
- Resin infiltration, Casein Phosphopeptide (CPP) - Amorphous Calcium Phosphate (ACP) - Fluoride
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Early Childhood Caries
The Caries-arresting Effect of Incorporating fTCP to NaF Varnish Applied Following AgNO3 in Preschool Children
The objective of this study is to compare the effectiveness of 25% AgNO3 solution plus 5% NaF varnish and 25% AgNO3 solution plus 5% NaF varnish with fTCP when applied semi-annually over 30 months in arresting dentine caries of…
- Trial name
- NCT03423797
- Testing
- 25% AgNO3 solution followed by 5% NaF, 25% AgNO3 solution followed by 5% NaF with fTCP
- Where
- China
- Volunteers
- 408 people
- Sponsor
- The University of Hong Kong
Dental Caries
Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03448107
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 3,345 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Oral Health Related Quality of Life, Early Childhood Caries
Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and Fill Technique
The clinical trial aims to compare children's oral health-related quality of life (OHrQL) following caries arrest technique using SDF versus conventional drill and fill in the children with ECC
- Trial name
- NCT05337449
- Testing
- silver diamine fluoride, conventional composite resin restoration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental
Arresting Carious Lesions With Minimal Intervention Techniques
A single-blinded randomized clinical trial with a split-mouth design that will assess the 12-month clinical and radiographic success of two minimally invasive treatment techniques, one using a chemo-mechanical caries removal…
- Trial name
- NCT06388746
- Testing
- BRIX3000®, Riva Star Aqua, SDI Limited, Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dental Caries
Effectiveness of SDF With Different Post-treatment Protocols in Arresting Dental Caries
To compare the effectiveness of the semi-annual application of 38% SDF with two post-treatment protocols in arresting dental caries in preschool children
- Trial name
- NCT05655286
- Testing
- 38% SDF treatment, not to rinse for at least 30 minutes after SDF treatment, rinse mouth immediately after SDF treatment
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Caries Arrest
Arresting Active Dentine Lesions and Quality of Life Among a Group of Preschool Children
Testing 3 different caries arresting techniques and the quality of life of a group of preschool children in Mansoura city, Egypt.
- Trial name
- NCT05314660
- Testing
- 38 % silver diamine fluoride, Atraumatic restorative technique, Ultra conservative dentistry
- Where
- Egypt
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mansoura University