Clinical trials: Caries Arrested
Dental Caries
Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03448107
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 3,345 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Dental Caries in Children, Satisfaction
Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress.
- Conditions
- Dental Caries in Children, Satisfaction, Cost Effectiveness, Oral Health
- Trial name
- NCT03480516
- Testing
- SDF, Fluoride varnish
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Dental Caries
Stopping Cavities Study: Diammine Silver Fluoride
This study is being conducted to test whether the use of diammine silver fluoride (also called silver diamine fluoride) hardens the cavity sufficiently so that it arrests.
- Trial name
- NCT02536040
- Testing
- 38% diammine silver fluoride, Water
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Advantage Dental Services, LLC
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba
Dental Caries
Fluoride Application on Preventing and Arresting Root Caries in Fluoridated and Non-fluoridated Areas
This study was a randomized clinical trial lasting for 24 months in two study sites, Hong Kong (water fluoridated) and Guangzhou (non-fluoridated area).
- Trial name
- NCT02742142
- Testing
- silver diammine fluoride
- Where
- 2 sites in China
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Early Childhood Caries
Effectiveness of SDF in Arresting Dental Caries in Preschool Children
Background: Tooth decay in children (Early childhood caries, or ECC) is a common childhood disease. Poor dentition significantly affects the nutrition, growth, development and general health of children.
- Trial name
- NCT02385474
- Testing
- 12% SDF, 38% SDF
- Where
- China
- Volunteers
- 888 people
- Sponsor
- The University of Hong Kong
Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization
Resin Infiltration and Fluoride Varnish Lesion Arresting Efficacy on Non-cavitated Proximal Lesion
Protection of dental hard tissues is one of the most important points of cariology. For this purpose, oral hygiene training (effective brushing and motivation), non-invasive approaches such as flouride varnish applications and…
- Conditions
- Dental Caries on Smooth Surface Limited to Enamel, Tooth Demineralization, Dental Caries, Dentistry, Operative
- Trial name
- NCT05202665
- Testing
- ICON DMG Resin Infiltration (micro-invasive approach), ClinproTM White Varnish, 3M ESPE Fluoride Varnish (non-invasive approach)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Caries in Children
Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries
The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative…
- Trial name
- NCT03063307
- Testing
- Atraumatic Restorative Treatment, Silver Diamine Fluoride
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Caries Arrested
Clinical and Laboratory Assessments of Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Caries Among Children and Parental Satisfaction
Globally, it is estimated that 2.4 billion people suffer from caries of permanent teeth and 486 million children suffer from caries of primary teeth .
- Trial name
- NCT04642846
- Testing
- Silver Diamine Fluoride (SDF)
- Where
- Saudi Arabia
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Khalood Saeed Bahammam
Dental Caries, Quality of Life
Silver Diamine Fluoride: A Randomized Controlled Trial on Its Effectiveness As A Caries Arresting Agent
The aim of the study is to assess the effectiveness of 38% Silver Diamine Fluoride (SDF) solution and to determine if it is superior to 5% NaF varnish in arresting carious lesions in the primary teeth of young children attending…
- Trial name
- NCT05008718
- Testing
- 38% SDF group, 5% NaF group
- Where
- Malaysia
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Dental Caries, Tooth Discoloration
Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment
This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth.
- Trial name
- NCT07886255
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Root Caries, NaF
The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial
The aim of this study is to summarize the current level of evidence on the prevalence of root caries in elderly population, evaluate the prevalence of root caries in elderly patients living in Canton Bern, Switzerland and to…
- Conditions
- Root Caries, NaF, SDF, Tooth Mousse
- Trial name
- NCT05765058
- Testing
- Group A, Group B, Group C
- Where
- Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Cavities of Teeth
Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions
This trial is a Phase III, multisite, randomized, placebo-controlled trial, with two parallel groups. The groups are SDF or placebo and they are applied every 6 months.
- Trial name
- NCT03649659
- Testing
- Silver Diamine Fluoride
- Where
- 3 sites in United States
- Volunteers
- 830 people
- Sponsor
- University of Michigan
Early Childhood Caries
Silver Diamine Fluoride Effectiveness Versus Atraumatic Restorative Treatment in Arresting ECC
The study was conducted to evaluate the effectiveness of the biannual application of 38% silver diamine fluoride in arresting early childhood caries when compared to atraumatic restorative treatment.
- Trial name
- NCT04514094
- Testing
- SDF, ART
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Hams Hamed Abdelrahman
Caries Roots, Flouride Varnish
Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults
Dental caries is a multifactorial, progressive disease which is the major causes of dental pain, infection and tooth loss. Dental caries can substantially compromise the quality of life in older adults 1 2.
- Conditions
- Caries Roots, Flouride Varnish, Caries; Dentin, Caries Arrested
- Trial name
- NCT04255251
- Testing
- Silver Diammine Fluoride, Fluoride Varnishes
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of New England
Dental Caries
Pharmacokinetics of Advantage Arrest in Children
The purpose of this study is to characterize basic PK parameters (Cmax, t1/2, AUC) in healthy children to contribute to evidence for the safety of Advantage Arrest, consistent with Guidance for Industry--Exposure--Response…
- Trial name
- NCT04186663
- Testing
- Silver Diamine Fluoride
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Dental Caries, Quality of Life
Comparative Effectiveness of School-based Caries Prevention
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03442309
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 7,418 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Incipient Caries
Clinical and Cost-Effectiveness of Silver Diamine Fluoride and Silver Fluoride, With or Without Application of LED, in Arresting Incipient Permament Molar Caries
The study aims to compare the effect of international brand ammonia based 38% SDF, water based silver fluoride solution (AgF), an aqueous silver fluoride solution, and local brand ammonia based SDF with and without LED light…
- Trial name
- SDF and AgF (NCT07366645)
- Testing
- International Sliver Diamine Fluoride, Local brand Egyptian Silver Diamine Fluoride, Silver Fluoride
- Volunteers
- 366 people
- Sponsor
- Cairo University
Oral Health Related Quality of Life, Early Childhood Caries
Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and Fill Technique
The clinical trial aims to compare children's oral health-related quality of life (OHrQL) following caries arrest technique using SDF versus conventional drill and fill in the children with ECC
- Trial name
- NCT05337449
- Testing
- silver diamine fluoride, conventional composite resin restoration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University