Clinical trials: Cataract
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Macular, Congenital Cataract
Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the macular development.
- Trial name
- NCT04077489
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- yin ying zhao
Cataracts
Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL
Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Trial name
- NCT05991960
- Testing
- Intervention
- Where
- 12 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataract, Lens Opacities
A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses
This is a prospective randomised open-label study with the aim to compare the visual performance of the trifocal FineVision® IOL versus the extended range of vision Symfony® IOL after phaco-emulsification cataract surgery.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03974451
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Inflammation
Clinical Trial on Anti-inflammatory Effect of Low-Molecular Weight Heparin in Pediatric Cataract Surgery
The purpose of this study is to determine if intraocular infusion of low-molecular weight heparin (enoxaparin) influences postoperative inflammation following pediatric cataract surgery with intraocular lens (IOL) implantation.
- Trial name
- NCT00986076
- Testing
- Enoxaparin, Balanced Salt Solution
- Where
- India
- Volunteers
- 23 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Bilateral Cataract, Unilateral Cataract
Comparison of the Safety and Efficacy of Ophtesis Bio 3% With a Similar 3% Sodium Hyaluronate OVD
Prospective, randomized, subject/evaluator-masked post market clinical study at up to 2 sites at Gemini eye clinic in Czech Republic. Randomization will be done by the eye surgeon.
- Trial name
- NCT05832749
- Testing
- Ophtesis Bio 3% ophthalmic viscosurgical device, Healon Endocoat 3% ophthalmic viscosurgical device
- Where
- 3 sites in Czechia
- Volunteers
- 296 people
- Sponsor
- Gemini Eye Clinic
Congenital Cataract
Iridocorneal Angle and Anterior Segment Structure in Eyes of Children With Cataract
The aim of this study is to evaluate the morphology of iridocorneal angle and anterior segment structure in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- ACA (NCT03778086)
- Testing
- gonioscopy
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
May-Hemalin, Fechtner Syndrome (Disorder)
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia
The research involves the establishment of a cohort including as much as possible cases of macrothrombocytopenia related to a "MYH9 syndrome" and the study of mutations and polymorphisms of MYH9 gene in all these patients.
- Conditions
- May-Hemalin, Fechtner Syndrome (Disorder), Epstein Syndrome (Disorder), MYH9 Related Disorders
- Trial name
- MAGIC-MYH9 (NCT00925236)
- Where
- France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University
Age Related Cataracts
Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens
This is a two-part, multi-center, investigator-initiated clinical study comparing visual outcomes and patient satisfaction in subjects receiving bilateral implantation of either the Clareon PanOptix intraocular lens (IOL) or a…
- Trial name
- NCT07006428
- Testing
- Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
- Where
- 3 sites in United States
- Volunteers
- 290 people
- Sponsor
- Argus Research Center, Inc.
Cataract, Artificial Intelligence
Validation of the Utility of Rare Disease Intelligence Platform
The prevention and treatment of diseases via artificial intelligence represents an ultimate goal in computational medicine. The artificial intelligence for systematic clinical application has not yet been successfully validated.
- Trial name
- NCT02748044
- Testing
- CC-Cruiser
- Where
- 4 sites in China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
The Incidence and Risk Factors of Glaucoma After Congenital Cataract Surgery
Correlative Study on Incidence and Risk Factors of Glaucoma-related Adverse Event at Various Durations After Congenital Cataract Surgery
A retrospective chart review of 264 eyes from 177 patients was performed who underwent congenital cataract surgery before the age of 14 years.
- Trial name
- NCT04521907
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Wenzhou Medical University
Congenital Cataract, Pediatric Cataract
Five-Year Visual Function and Refractive Outcomes After Congenital Cataract Surgery
This prospective multicenter observational study aims to evaluate the 5-year visual function and refractive outcomes in children undergoing surgery for congenital cataract.
- Trial name
- NCT07070037
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Aphakia Cataract
Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study
This is an observational, follow up study of subjects previously enrolled in the "RxSight Light Adjustable Lens (LAL) and Light Delivery Device (LDD) New Enrollment Study".
- Trial name
- NCT07347379
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD)
- Where
- 6 sites in United States
- Volunteers
- 108 people
- Sponsor
- RxSight, Inc.
Pediatric Cataract
Outcome of Capsular After Pediatric Cataract Surgery With Primary Intraocular Lens Implantation
The aim of this study is to evaluate the outcome of capsular in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- Capsular (NCT04357249)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Primary Angle-Closure Glaucoma
Predicting the Risk of Partial Ciliary Block After Cataract and Goniosynechialysis Surgery in Primary Angle-Closure Disease
Primary angle-closure disease (PACD) is a major cause of vision loss, often treated with a combined surgery that removes the eye's natural lens (cataract surgery) and physically opens the eye's drainage system…
- Trial name
- PCB-Risk (NCT07549438)
- Volunteers
- 1,150 people
- Sponsor
- Peking University People's Hospital
Cataract, Healthy
Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts
This study will use a newly developed instrument called dynamic light scattering device (DLS) to examine age-related changes in the human lens and to study the causes and development of cataracts.
- Trial name
- NCT00007215
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract
Comparison of Artificial Intelligent Clinic and Normal Clinic
In this study, the investigators provide participants≤14 years old the artificial intelligent clinic or normal clinic in the purpose of seeking out a better way to make a definite diagnosis with high efficiency and accuracy, and…
- Trial name
- NCT03240848
- Testing
- artificial intelligent clinic, normal clinic, experts diagnose
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Congenital Cataract
Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery
Previously, we have developed a minimal invasive lens surgery in the purpose of reduce post-operative complications of congenital cataract.
- Trial name
- NCT03230799
- Testing
- minimal invasive lens surgery, traditional cataract surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract
Capsulorhexis Size and Capsular Outcome
Different capsulorhexis size results in different capsular outcome when treating pediatric cataract, and there should be an appropriate capsulorhexis size for the best capsular outcome.
- Trial name
- NCT02158325
- Testing
- anterior capsulorhexis sizes
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Sun Yat-sen University