Clinical trials: Cerebral Palsy, Dyskinetic
Cerebral Palsy, Dyskinetic, Secondary Dystonia
Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects
The primary objective of the proposed study is to evaluate the safety of ExAblate Transcranial MRgFUS as a tool for creating bilateral or unilateral lesions in the globus pallidus (GPi) in patients with treatment-refractory…
- Trial name
- NCT06036199
- Testing
- Focused Ultrasound Pallidotomy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's National Research Institute
Cerebral Palsy, Gait Disorders
The Effects of Exoskeletal Robot-Assisted Gait Training on Children With Cerebral Palsy: A Pilot Study
Cerebral Palsy (CP) is a complex neurodevelopmental disorder caused by early brain injury, leading to motor impairments such as muscle weakness, stiffness, and gait instability, which impact daily functioning.
- Conditions
- Cerebral Palsy, Gait Disorders, Gait Disorders in Children, Gait Disorders, Neurologic
- Trial name
- NCT05759182
- Testing
- Powered Exoskeleton Gait Training
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- COSMO ROBOTICS CO., Ltd
Cerebral Palsy, Dyskinetic
A Study to Test if TEV-50717 is Safe and Effective in Relieving Abnormal Involuntary Movements in Cerebral Palsy
Study TV50717-CNS-30081 is a 55-week study in which participants who have successfully completed the parent study (Study TV50717-CNS-30080) may be eligible to enroll in this study.
- Trial name
- NCT04200352
- Testing
- TEV-50717
- Where
- 30 sites in United States, Denmark and 7 more
- Volunteers
- 44 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic
Functional Benefits of Multisite Surgery for the Upper Limb of Children With Cerebral Palsy
The aim of the study is to investigate the impact of individualized multisite neuro-orthopedic surgery of the upper limb in children with Cerebral Palsy on unilateral functional capacities and bimanual performance.
- Conditions
- Cerebral Palsy, Spastic, Cerebral Palsy, Dyskinetic, Infantile Hemiplegic Cerebral Palsy
- Trial name
- NCT04395729
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Cerebral Palsy
Efficacy of Axial Stability on Improving Gait and Balance Performance in Children With Dyskinetic Cerebral Palsy
The aim of this study will be to evaluate the effect of TheraTogs orthotic undergarment and strapping system on increasing axial stability that will reflect on improving balance and walking performance in children with dyskinetic…
- Trial name
- NCT03037697
- Testing
- TheraTogs Arm, Traditional Treatment
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Dyskinetic Cerebral Palsy Due to Perinatal Hypoxia
Effect of DBS on Quality of Life in Dyskinetic Cerebral Palsy
There are limited therapeutical options for patients with secondary dystonia due to cerebral palsy. Pharmacotherapy is often without effect, or side effects are severe.
- Trial name
- STIM-CP (NCT02097693)
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- University Hospital of Cologne
Cerebral Palsy (CP)
Effects of Body Weight Supported Treadmill Training on Motor Development in Patients With Dyskinetic Cerebral Palsy
This randomized controlled trial will evaluate motor development outcomes in children aged 5-12 years with dyskinetic cerebral palsy.
- Trial name
- BWSTT DCP (NCT07263542)
- Testing
- BODY WEIGHT SUPPORTED TREADMILL TRAINING, BOBATH THERAPY
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Dyskinesia, Cerebral Palsy
Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy
The primary objective of this study is to evaluate the efficacy of valbenazine versus placebo on improving chorea in pediatric and adult participants who have dyskinesia due to cerebral palsy (DCP) with choreiform movements.
- Trial name
- NCT05206513
- Testing
- Valbenazine
- Where
- 38 sites in United States, Argentina and 8 more
- Volunteers
- 86 people
- Sponsor
- Neurocrine Biosciences
Cerebral Palsy, Dyskinetic
Family-Centered Physiotherapy in Dyskinetic Cerebral Palsy
This study aimed to examine the impact of family centered, goal-oriented physiotherapy and rehabilitation on body function, activity, participation, and quality of life in severely affected children with dyskinetic cerebral palsy…
- Trial name
- NCT06532513
- Testing
- Family-Centered Goal-Oriented Physiotherapy and Rehabilitation Application
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Hacettepe University
Cerebral Palsy, Dyskinetic
A Study of TEV-50717 (Deutetrabenazine) for the Treatment of Dyskinesia in Cerebral Palsy in Children and Adolescents
CP (cerebral palsy) refers to a group of neurological disorders that appear in infancy or early childhood and permanently affect body movement and muscle coordination.
- Trial name
- RECLAIM-DCP (NCT03813238)
- Testing
- TEV-50717
- Where
- 70 sites in United States, Belgium and 10 more
- Volunteers
- 63 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Athetoid CP, Cerebral Palsy (CP)
Comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children With Athetoid Cerebral Palsy: A Randomized Controlled Trial
This is an RCT aiming to explore the comparison of Sensory Integration Therapy and Conventional Physical Therapy on Gross Motor Function in Children with Athetoid Cerebral Palsy
- Trial name
- NCT07611565
- Testing
- Sensory Integration Therapy and Conventional Physical Therapy, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Ibadat International University, Islamabad
Dyskinetic Cerebral Palsy, Dystonic Cerebral Palsy
Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults
The purpose of this study is to test the safety of placing Deep Brain Stimulators (DBS) in a part of the brain called the cerebellum and using electrical stimulation of that part of the brain to treat movement symptoms related to…
- Trial name
- NCT06122675
- Testing
- DBS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Pediatric Disorder, Genetic Predisposition
Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy
This study looks at how a medicine called trihexyphenidyl works in children with dystonic cerebral palsy. The study aims to understand how trihexyphenidyl is broken down and used in the body of pediatric patients and whether this…
- Conditions
- Pediatric Disorder, Genetic Predisposition, Dystonia, Secondary, Dystonia
- Trial name
- TRIKE2 (NCT06554288)
- Testing
- Trihexyphenidyl
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's Mercy Hospital Kansas City