Clinical trials: Cesarean Sections
Dysbiosis, Prophylaxis
Lactobacillus Reuteri DSM 17938 in Gut Microbiota Development in Infant Born by Caesarean Section
The aim of this study is to assess influence of probiotic Lactobacillus reuteri DSM 17938 on formation of gut microbiota in infant born by Caesarean section.
- Trial name
- NCT03675048
- Testing
- BioGaia Protectis drops
- Where
- Russia
- Volunteers
- 97 people
- Sponsor
- BioGaia AB
Pregnancy, Obese
Self-Retaining Retractor in Obese Patients Undergoing Cesarean Section
The purpose of this study is to investigate the effects of the Alexis O C-section retractor in obese patients (BMI ≥30 kg/m2) who undergo Cesarean sections.
- Trial name
- Alexis (NCT01826604)
- Testing
- Alexis O C-Section Retractor, Control- Conventional retractors
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- St. Louis University
Pregnancy
Previous Cesarean Sections
This is a retrospective chart review. The purpose is to look at the outcomes for women and newborns who decided to attempt a trial of labor after 3 or more previous cesarean sections.
- Trial name
- NCT03024632
- Testing
- Trial of labor
- Sponsor
- St. Louis University
Wound
Staples Versus Suture for Cesarean Wound Closure
The objective of this randomized controlled trial is to compare wound morbidity (including disruption and infection) in surgical staples versus absorbable subcuticular suture for wound closure in cesarean deliveries.
- Trial name
- SVS (NCT01008449)
- Testing
- Surgical staples, Absorbable Surgical Suture
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of Alabama at Birmingham
Vaginal Delivery
Role of the Intrapartum Grobman Nomogram in the Indication of Attempted Vaginal Delivery After Cesarean Section
The rate of pregnant patients with a history of cesarean section is increasing. Caesarean section is a surgery which is not without risk and in particular concerning the risk of uterine rupture and malplacentation during a new…
- Trial name
- GPP (NCT06202768)
- Testing
- data collection
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Central Hospital, Nancy, France
Fetomaternal Transfusion
Effect of Placental Drainage of Fetal Blood at Cesarean Section on the Incidence of Feto-Maternal Transfusion
Study hypothesis: umbilical cord drainage of fetal blood after delivery of the infant would reduce the incidence of feto-maternal transfusion.
- Trial name
- NCT00470899
- Testing
- drainage of placenta of fetal blood
- Volunteers
- 86 people
- Sponsor
- Lester E. Cox Medical Centers
Neonatal Adaptation
Effect of Immediate Skin-to-Skin Contact on Neonatal Heart Rate Variability After Cesarean Secton
At birth, both the newborn and the mother experience adaptive stress, which can be measured using objective physiological methods.
- Trial name
- HRV-SCENE (NCT07109076)
- Testing
- skin-to-skin contact, routine care
- Where
- Slovenia
- Volunteers
- 80 people
- Sponsor
- University Medical Centre Ljubljana
Overweight and Obesity, Allergy
Effects of Vaginal Seeding on Infants' Body Mass Index and Allergy Risk for Caesarean-delivered Children
This is a single-blind randomized controlled trial, aiming to evaluate the effects of vaginal seeding on body mass index as well as allergy risk for cesarean-delivered infants.
- Trial name
- NCT03809390
- Testing
- Vaginal seeding
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Peking University
Pain, Postoperative
Efficacy of Bupivacain Local Infiltration for the Management of Pain During Cesarean Section
This study aims to evaluate the effect of local administration of bupivacain in the cesarean section incision for postoperative pain control, using the visual analogue pain scale (VAS) and assessing the need for rescue analgesia…
- Trial name
- NCT05404490
- Testing
- Bupivacain
- Where
- Panama
- Volunteers
- 202 people
- Sponsor
- Saint Thomas Hospital, Panama
Maternal Blood Loss During Cesarean Delivery
Uterine-Angle Clamping During Delayed Cord Clamping at Cesarean Delivery
This randomized controlled study evaluated whether temporary clamping of the lateral angles of the uterine incision during a standardized 60-second delayed umbilical cord-clamping period reduces maternal blood loss in women…
- Trial name
- UAC-DCC (NCT07866352)
- Testing
- Temporary Uterine-Angle Clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 248 people
- Sponsor
- Baskent University
Obesity
The Effect of Traxi Panniculus Retractor on Surgical Time at Non-emergent Cesarean Delivery in Obese Women
This is an unblinded, randomized control trial of obese women to evaluate the impact of the Traxi Panniculus Retractor (TPR) on the cesarean operative time and surgical blood loss when compared to silk tape.
- Trial name
- NCT04458415
- Testing
- Traxi Panniculus Retractor (TPR), Silk Tape
- Where
- United States
- Sponsor
- Geisinger Clinic
Previous Cesarean Section Scar
Clinical and Ultrasound Score for Evaluation of Previous Cesarean Section Scar
Cesarean delivery rates have increased dramatically worldwide. In the United States, cesarean section (CS) rates increased from 5% of all deliveries in 1970 to a high of 31.9% in 2016.Although efforts were made to reduce the…
- Trial name
- NCT04856254
- Testing
- Trial of labor after cesarean section
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Fecal Microbiota Transplantation, Cesarean Section
Health Outcomes in C-Section Infants With Fecal Microbiota Transplantation
This single-center randomized controlled trial evaluates whether donor-derived fecal microbiota transplantation (FMT) administered within 6 hours after birth can improve gut microbiota development and reduce the risk of…
- Conditions
- Fecal Microbiota Transplantation, Cesarean Section, Overweight and Obesity
- Trial name
- SISU-FMT (NCT06282952)
- Testing
- Donor-derived fecal microbiota transplantation
- Where
- Finland
- Volunteers
- 460 people
- Sponsor
- Oulu University Hospital
Epidural Top-up, Labour
Labour Epidural Top-up With Warmed Ropivacaine
The purpose of this study is to determine weather using warmed (body temperature) 0.75% Ropivicaine to convert labour epidural analgesia to surgical anaesthesia, reduces the onset time of surgical block, compared to standard room…
- Conditions
- Epidural Top-up, Labour, Caesarian Section, Ropivacaine
- Trial name
- LETWR (NCT02838329)
- Testing
- warming of ropivacaine for BT, Ropivicaine
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Pain
Does a Perioperative Course of Gabapentin Improve Analgesia After Cesarean Delivery?
Gabapentin has been very effective at treating pain after knee and hip operations, hysterectomies, and many other types of operations.
- Trial name
- NCT01848119
- Testing
- Gabapentin, lactose
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Short Interpregnancy Interval
Short Interpregnancy Interval After One Prior Cesarean Delivery and Risk of Intraoperative Maternal Morbidity
To determine if a short interpregnancy interval following a prior cesarean delivery is associated with an increased risk of intraoperative maternal morbidity (e.g., hemorrhage, visceral injury, prolonged surgery) during the next…
- Trial name
- NCT07525362
- Volunteers
- 80 people
- Sponsor
- Assiut University
Cesarean Section
Two Syringe Spinal Anesthesia Technique for Cesarean Section: A Simple Way to Achieve More Satisfactory Block and Less Hypotension
Background: Poor spinal anaesthesia block is common and is difficult to manage; so a technique to minimize its incidence is advisable. Hypotension is the commonest problem with spinal anesthesia.
- Trial name
- NCT02577432
- Testing
- fentanyl, Hyperbaric bupivacaine
- Volunteers
- 124 people
- Sponsor
- Dr. Soliman Fakeeh Hospital
Asphyxia Neonatorum, Fetal Hypoxia
Sustained Cord Circulation at Emergency Cesarean Section
The goal of this clinical trial is to evaluate if sustained cord circulation during resuscitation improves outcomes for term neonates born by emergency Cesarean section.
- Trial name
- SUCCECS (NCT06540222)
- Testing
- Sustained cord (≥ 180 seconds) resuscitation, Routine (< 60 seconds) cord clamping
- Where
- 12 sites in Sweden
- Volunteers
- 2,200 people
- Sponsor
- Region Skane
Placenta Accreta Spectrum
Risk Factors, Prognosis and Prediction Models for Placenta Accreta Without Prior Cesarean Section
1. Identify the risk factors for Placenta accreta spectrum (PAS) disorders in women without prior caesarean section (CS). 2. Clarify the prognostic factors of the disease and explore individualized treatment options to improve…
- Trial name
- NCT06383923
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Nurse's Role, Breastfeeding
Effect of Skin to Skin Contact on Sucking Efficiency of Newborns and Breastfeeding Self Efficacy of Mothers in Cesarean Deliveries
Due to the separation of the mother and the baby after the cesarean section, initiation of breastfeeding by the mother of the newborn in the first hour of life is delayed.
- Trial name
- NCT05697653
- Testing
- Skin-to-Skin contact.
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University