Clinical trials: Chatbot, open to volunteers
Epilepsy, Seizure
AI-Based Mobile Intervention on Medication Non-Adherence and Transition
This study aims to examine whether the AI-personalized version of the Medilepsy® app is more effective than the non-AI (standard version without AI personalization) can improve key outcomes, such as medical adherence and…
- Trial name
- NCT07445074
- Testing
- Medilepsy® Chatbot AI-Enhanced, Medilepsy® Chatbot Standard
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Central Florida
Prevenir el Embarazo Adolescente
"Educational Intervention 'Be Yourself': Digital Innovation to Prevent Teenage Pregnancy"
Introduction: Adolescent pregnancy and early initiation of sexual activity is a serious global public health problem, every year, around sixteen million adolescents between 15 and 19 years of age give birth, representing 11% of…
- Trial name
- BYE-Chat (NCT06824922)
- Testing
- "Be yourself", educational intervention with chatbot to promote self-determined motivation and prevent adolescent pregnancy: pilot trial protocol, Conventional Sex Education
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
HPV Vaccination Rates, HPV Vaccine Awareness
Effectiveness of Large Language Model-Based Chatbot Among Parents of Junior High School Girls in Improving Human Papillomavirus (HPV) Vaccine Awareness, Intention and Vaccination Rates
This is an interventional study targeting parents of junior high school girls. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates among parents' junior high…
- Conditions
- HPV Vaccination Rates, HPV Vaccine Awareness, HPV Vaccination Intention
- Trial name
- NCT07525245
- Testing
- Scientific videos, Vaccine chatbot
- Volunteers
- 18,000 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Internet Gaming Disorder, Social Media Addiction
Chatbot Intervention to Reduce Common Digital Addictions, Sedentary Behaviors and Mental Distress Among Adolescents
The goal of the study is to investigate the efficacy of a secondary low-intensity stage of change (SoC) and motivational interviewing (MI)-based Chatbot-assisted intervention in reducing digital addictions in adolescents with…
- Trial name
- NCT06821373
- Testing
- Chatbot, Control
- Where
- Hong Kong
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
AI-CBT Intervention Group, Waitlist Control Group
AI-Based CBT Chatbot for Adolescent Social Anxiety
The goal of this clinical trial is to learn if a CBT-based AI chatbot works to reduce social anxiety in teenagers. It will also look at how the chatbot works, including changes in thinking patterns, emotion management, and safety…
- Trial name
- NCT07897084
- Testing
- AI-CBT intervention group
- Volunteers
- 120 people
- Sponsor
- Central China Normal University
Eating Disorders, Anorexia Nervosa
Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders
The goal of this study is to develop and refine an artificial intelligence (AI)-powered Exposure Therapy for Eating Disorders chatbot web-app that effectively engages adolescents and young adults and decreases anxiety about…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT07237607
- Testing
- "Exp-ED" Digital Exposure-Therapy Chatbot app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Adolescent Idiopathic Scoliosis (AIS), Psychological Health
Evaluation of a Chatbot-Delivered Structured Psychological Intervention for Teenagers With Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis is the most common spinal deformity in children and can significantly impact the psychological health of affected teenagers.
- Trial name
- NCT06698952
- Testing
- Intervention Group, control group
- Volunteers
- 52 people
- Sponsor
- The Hong Kong Polytechnic University
Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources
AI-Based Personalized Health and Self-Care
The goal of this clinical trial is to learn if the DAPHNE chatbot can improve caregiver engagement, usability, and integration of social care support tools into clinical workflows in caregivers of pediatric patients receiving…
- Conditions
- Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources, Primary Health Care and Access to Primary Care, Technology Use to Support Caregivers
- Trial name
- NCT07168382
- Testing
- DAPHNE Chatbot Intervention, Standard HRSN Screening and Referral (Usual Care)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Emre Sezgin
Anxiety, Depression in Adolescence
Co-designing Adaptations of a Digital Mental Health Intervention (Wysa) for Adolescent Girls With Anxiety or Depression in Rural India
The goal of this study is to culturally and contextually adapt Wysa, an evidence-based AI-powered digital mental health intervention (DMHI), for adolescent girls (ages 13-18) with symptoms of anxiety and/or depression in rural…
- Conditions
- Anxiety, Depression in Adolescence, Anxiety Disorder of Adolescence
- Trial name
- NCT07595029
- Testing
- Digital psychosocial tool
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Wysa
Smoking Cessation
Optimizing Chatbot Reminder Timing in a Chatbot Cessation Service: A Micro-Randomized Trial
The goal of this study is to learn whether the timing of weekly chatbot reminders affects user engagement with the chatbot cessation service.
- Trial name
- NCT07826884
- Testing
- Chatbot Cessation Service With Randomized Reminder Timing
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- The University of Hong Kong
Depression, Suicidal Ideation
Social Media Intervention for Online Victimized Youth
This feasibility pilot trial seeks to examine the feasibility and target engagement of a coping skills and psychoeducational intervention delivered via an automated conversational chatbot named SMILEY in reducing frequency and…
- Trial name
- SMILEY (NCT06835985)
- Testing
- Chatbot Intervention, Brief Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Pittsburgh
Therapeutic Communication
Culturally-Tailored AI Chatbot Simulation for Therapeutic Communication and Empathy in Psychiatric Nursing Students
Therapeutic communication and empathy are core competencies in psychiatric nursing, yet students often have limited opportunities to practise them safely with culturally realistic patients and families.
- Trial name
- AI-CHAT-PSY (NCT07905469)
- Testing
- Culturally-Tailored AI Chatbot Simulation, Instructor-Facilitated Peer Role-Play
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Non-suicidal Self-injury (NSSI)
Acceptance and Commitment Therapy-Based Chatbot for Non-suicidal Self-Injury in Adolescents
The purpose of this study is to evaluate the feasibility and effectiveness of a self-guided digital Acceptance and Commitment Therapy (ACT) intervention for adolescents who engage in non-suicidal self-injury (NSSI).
- Trial name
- NCT07848620
- Testing
- ACT-Based Chatbot
- Volunteers
- 100 people
- Sponsor
- Central China Normal University
Depressive Symptoms, Mental Health (Depression)
Using a School-Based Depression Literacy Psychoeducation Program With AI Chatbot to Improve Depression Literacy and Help-Seeking Among High School Students
The primary purpose of this randomized controlled trial is to evaluate the effectiveness of an AI chatbot enhanced school-based depression literacy psychoeducational program, combined with a resource navigation booklet, on high…
- Trial name
- NCT07790731
- Testing
- school-based depression literacy program
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Chang Hsiu-Ju
Chatbot, Large Language Model
Effects of a Large Language Model-Driven Chatbot on Reproductive Concerns After Cancer
Reproductive health has emerged as a critical yet overlooked concern among Adolescent and Young Adult (AYA) cancer survivors, given their compromised potential for biological parenthood in prime childbearing years.
- Conditions
- Chatbot, Large Language Model, Adolescent and Young Adult Cancer Survivors, Reproductive Health
- Trial name
- NCT07741266
- Testing
- Chatbot, Electronic brochure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
HIV Infections, Breast Cancer
The MARVIN Chatbots to Provide Information for Different Health Conditions
This research is a continuation of a usability study with the MARVIN chatbot. The investigators aim to adapt the MARVIN chatbot to open it to other health domains (e.g. breast cancer) and populations (e.g. pharmacists).
- Conditions
- HIV Infections, Breast Cancer, Pediatric Emergency Medicine
- Trial name
- NCT05789901
- Testing
- MARVIN, MARVIN-Pharma, MARVINA
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
HPV Vaccine
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy
The goal of this clinical trial is to learn if a chatbot powered by artificial intelligence works to improve HPV vaccination among females aged 15 to 45 in China.
- Trial name
- NCT07200570
- Testing
- LLM-Powered HPV Vaccine Chatbot
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Fudan University
AI Chatbot, Nursing Education
The Effect of Artificial Intelligence-Supported Intramuscular and Subcutaneous Injection Training on Nursing Students
The complexity of healthcare services and technological advances today have necessitated the adoption of innovative approaches in nursing education.
- Conditions
- AI Chatbot, Nursing Education, AI (Artificial Intelligence), Nursing Skills
- Trial name
- NCT07253571
- Testing
- Training of IM and SC injection skills via Chatbot
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Body Image Disturbance, Disordered Eating Behaviors
Adolescent Chatbot
The purpose of this study is to test an eating disorders prevention digital chatbot program in a diverse group of adolescents.
- Conditions
- Body Image Disturbance, Disordered Eating Behaviors, Eating Disorder Prevention
- Trial name
- EMBody (NCT07094503)
- Testing
- Wysa Digital Chatbot Program
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Washington University School of Medicine
Perinatal Opioid Use Disorder, Opioid Use Disorder
Adapting the Penny Chatbot for Perinatal OUD Patients: COPILOT
To address both loneliness and engagement in perinatal and OUD care among perinatal women, the investigators plan to adapt an existing texting support chatbot, Penny, to make it appropriate for use by women who are pregnant and…
- Trial name
- PENNY-COPILOT (NCT06969261)
- Testing
- Penny COPILOT
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania