Clinical trials: Chest Syndrome
Post-Mastectomy Chronic Pain Syndrome
Radiofrequency Thoracic Sympathectomy for Chronic Postmastectomy Pain; Randomized Placebo Controlled Study
Postmastectomy pain syndrome (PMPS) is a neuropathic pain that can follow surgical treatment for breast cancer, The antineuropathic medications (antidepressants and anticonvulsants) are disappointing and have low success rate.
- Trial name
- NCT03494426
- Testing
- radiofrequency thoracic sympathectomy, pregabalin ,tramadol,and tricyclic antidepressants
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Sickle Cell Disease, Asthma
Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial
Acute and chronic pulmonary complications with concomitant inflammatory response are a leading cause of morbidity and mortality in children with sickle cell disease (SCD).
- Conditions
- Sickle Cell Disease, Asthma, Acute Chest Syndrome
- Trial name
- NCT02187445
- Testing
- Budesonide inhalation suspension
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Vanderbilt University
Marfan Syndrome, Turner Syndrome
National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions
The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) was initiated in 2006 by the National Heart, Lung, and Blood Institute (NHLBI) and the National Institute of…
- Conditions
- Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome
- Trial name
- GenTAC (NCT01322165)
- Where
- 7 sites in United States
- Volunteers
- 3,706 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myasthenia Gravis, Autoimmune Diseases of the Nervous System
Predictors and Prognostic Factors of Myasthenia Gravis Outcome
This study aims to characterize the clinical features, frequency of different subgroups of MG, and identify predictors of treatment responsiveness among different subgroups of MG.
- Conditions
- Myasthenia Gravis, Autoimmune Diseases of the Nervous System, Neuromuscular Junction Diseases, Thymoma
- Trial name
- NCT05214612
- Testing
- Drug treatment of myasthenia gravis and treatment of crisis
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Diaphragm Ultrasound, Electrical Cardiometry
Diaphragmatic Ultrasound and Thoracic Fluid Content for Prediction of Non-Invasive Ventilation Failure in Neonates
This research assessed diaphragmatic ultrasound and thoracic fluid content (TFC) as potential early predictive tools for detecting NIV failure in preterm neonates.
- Conditions
- Diaphragm Ultrasound, Electrical Cardiometry, Non Invasive Ventilation (NIV), RDS of Prematurity
- Trial name
- NCT07148102
- Testing
- Diaphragmatic US, EC
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Lamiaa Khaled Zidan
Sickle Cell Disease
Quantifying the Presence of Lung Disease and Pulmonary Hypertension in Children With Sickle Cell Disease
The proposed research study is a cross-sectional study enrolling young children with sickle cell disease between 5 and 12 years of age.
- Trial name
- NCT01895998
- Testing
- Albuterol
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Respiratory Distress Syndrome, Newborn, Neonatal Respiratory Distress
Chest Ultrasound as Diagnostic and Prognostic Tool in Neonatal RDS
This cross-sectional study aims to evaluate the diagnostic accuracy of chest ultrasound in neonatal respiratory distress syndrome and to assess its potential prognostic value compared with chest X-ray.
- Trial name
- NCT07857304
- Volunteers
- 82 people
- Sponsor
- Assiut University
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Thoracic Insufficiency Syndrome
A Retrospective Review of Early Onset Spinal Deformity Patients Treated With the Ellipse MAGEC System
The purpose of this study is to determine the safety profile and probable benefit of the Ellipse Technologies Inc. MAGEC System in subjects with early onset spinal deformity associated with thoracic insufficiency syndrome.
- Trial name
- NCT01716936
- Where
- 15 sites in Egypt, Finland and 5 more
- Volunteers
- 54 people
- Sponsor
- Ellipse Technologies, Inc.
Sickle Cell Disease, Acute Chest Syndrome
Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome
This study evaluates the safety of defibrotide in subjects with sickle cell disease (SCD)-associated acute chest syndrome (ACS).
- Trial name
- NCT03805581
- Testing
- Defibrotide
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York Medical College
RDS of Prematurity
Sustained Lung Inflation With CPAP in Preterm Neonates (SI-CPAP)
Neonatal respiratory distress syndrome (RDS) is the most common cause of respiratory failure in the first few days in life. It is characterized by the tendency of alveoli and terminal bronchioles to collapse due to the lack of…
- Trial name
- SI-CPAP (NCT03916523)
- Testing
- Sustained lung inflation, Continuous positive airway pressure (CPAP), Mechanical ventilation
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Graft Versus Host Disease, Leukemia
Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases
RATIONALE: Umbilical cord blood transplantation may be able to replace cells destroyed by chemotherapy or radiation therapy. PURPOSE: Phase II trial to study the effectiveness of umbilical cord blood transplantation in treating…
- Conditions
- Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Thymic Carcinoma
- Trial name
- NCT00003662
- Testing
- anti-thymocyte globulin, busulfan, cyclophosphamide
- Where
- 15 sites in United States
- Volunteers
- 90 people
- Sponsor
- Roswell Park Cancer Institute
Aortic Arch, Aortic Arch Aneurysm
Outcome of a Triple Inner Branched Aortic Arch Stentgraft. A Prospective, Multicenter Registry.
Outcome of a triple inner branched aortic arch stentgraft. A prospective, mulitcenter registry.
- Conditions
- Aortic Arch, Aortic Arch Aneurysm, Dissection of Aortic Arch, Triple Branch
- Trial name
- triple_branch (NCT05530304)
- Testing
- Triple inner branched arch stentgraft
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Muenster
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
Valiant Thoracic Stent Graft With the Captivia Delivery System in the Treatment of Descending Thoracic Aortic Diseases (VALIANT CAPTIVIA France)
The objective of this study is to assess the benefits of endovascular technique in terms of efficacy and safety of Valiant Thoracic Stent Graft with the Captivia Delivery System in the treatment of thoracic aortic disease, in a…
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Penetrating Ulcer, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT01775046
- Testing
- DTA patients (Valiant)
- Where
- 17 sites in France
- Volunteers
- 160 people
- Sponsor
- Medtronic Cardiovascular
Children, Only, Upper Crossed Syndrome
Effect of Mat Pilates on Pain and Postural Alignment in School Going Children With Upper Crossed Syndrome.
This randomized control clinical Trial is to evaluate the effect of mat Pilates on postural alignment and pain levels in school-going children with Upper Crossed Syndrome.
- Trial name
- NCT07244068
- Testing
- Mat Pilates and Routine Physical Therapy, Routine Physical Therapy (RPT)
- Where
- Pakistan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Thoracic Aortic Aneurysm, Thoracic Aorta Injury
CTAG Dissection/Trauma Post Marketing Surveillance Japan
Post Marketing Surveillance of the Conformable GORE® TAG® Thoracic Endoprosthesis
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aorta Injury, Thoracic Aortic Dissection
- Trial name
- NCT05414318
- Testing
- Conformable GORE® TAG® Thoracic Endoprosthesis
- Volunteers
- 55 people
- Sponsor
- W.L.Gore & Associates
Aortic Dissection, Aortic Diseases
Antibiotic Prophylaxis for TEVAR
The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of…
- Conditions
- Aortic Dissection, Aortic Diseases, Aortic Aneurysm, Thoracic, Coarctation of Aorta
- Trial name
- NCT05405790
- Testing
- thoracic endovascular aortic repair
- Where
- China
- Volunteers
- 457 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Cancer, Metastatic, Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and…
- Conditions
- Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
- Trial name
- NCT03452774
- Testing
- Clinical Trial Matching
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 50,000 people
- Sponsor
- Massive Bio, Inc.
Sickle-Cell Disease Nos With Crisis
Pulmonary Ultrasound in the Diagnosis of Acute Thoracic Syndrome in Vaso-occlusive Sickle Cell Crisis
ATS (acute thoracic syndrome) refers to acute pulmonary involvement in a sickle cell patient. The diagnosis is based on the association of clinical signs (fever or respiratory symptoms) with a recent pulmonary infiltrate on the…
- Trial name
- ECHO-STA (NCT03971136)
- Testing
- pulmonary ultrasound
- Where
- 4 sites in France
- Volunteers
- 190 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Chest Pain, Acute Coronary Syndrome
The Evaluation and Management of Patients With Acute Chest Pain in China
The purpose of this study is to describe the characteristics, evaluation, management and outcomes of acute chest pain, and to provide opportunities for future initiatives to improve the emergency care for patients experiencing…
- Trial name
- NCT02384863
- Where
- 7 sites in China
- Volunteers
- 18,000 people
- Sponsor
- Yuguo Chen