Clinical trials: Chiari Malformation Type 2
Keratoconus
Study of the Safety and Effectiveness of Photochemically Induced Collagen Cross-Linking in Eyes With Keratoconus.
This study is being conducted to assess the safety and effectiveness of photochemically induced collagen cross- linking (CCL) at irradiance of 18mW/cm2 in eyes with Keratoconus and Ecstasia.
- Trial name
- NCT02762253
- Testing
- Riboflavin drops
- Where
- 11 sites in United States
- Volunteers
- 320 people
- Sponsor
- Nvision Laser Eye Centers
Open Spina Bifida, Myelomeningocele
Fetoscopic Open Spina Bifida Repair Using the SAFER Technique
Children submitted to fetoscopic in utero myelomeningocele repair using the SAFER (Skin-over-biocellulose for Anternatal FEtoscopic Repair) technique will evaluate at 30 months or more, regarding ambulation, neurodevelopment…
- Conditions
- Open Spina Bifida, Myelomeningocele, Meningomyelocele, Chiari Malformation With Spina Bifida
- Trial name
- NCT04356703
- Testing
- Neuropsicomotor developmental test
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Israelita Albert Einstein
Myelomeningocele, Brain Malformation
The Role of CSF in Chiari II Brain Malformation
Spina bifida, particularly its most severe form known as open spina bifida (myelomeningocele), is a significant congenital disorder that results in profound neurological impairments, including Chiari II malformation.
- Conditions
- Myelomeningocele, Brain Malformation, Chiari Malformation Type 2
- Trial name
- NCT06560788
- Testing
- collection of cerebrospinal fluid
- Volunteers
- 18 people
- Sponsor
- University College, London
Unstable Corneas
Corneal Cross-Linking Comparing Variables
The purpose of this study is to evaluate the Safety and Efficacy of Corneal Cross Linking in a Continuous Beam versus Pulsed Treatments across epithelium on and epithelium off surfaces.
- Trial name
- NCT02095730
- Testing
- Epithelium-On Riboflavin, Epithelium-Off Riboflavin, UV Light - Continuous Beam
- Where
- 16 sites in United States
- Volunteers
- 500 people
- Sponsor
- Crowd Health Research, LTD
Fetal Anomaly, Spinal Dysraphism
An Audit of the Posterior Fossa Characterization in Open Spina Bifida Based on Tertiary Center Experience
Brain stem and posterior fossa measurements in spina bifida aperta fetuses to compare them with normal population. Additionally, Describe the difference between pre- and postoperative findings.
- Conditions
- Fetal Anomaly, Spinal Dysraphism, Chiari Malformation Type 2
- Trial name
- NCT03544970
- Where
- Belgium
- Volunteers
- 316 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven