Clinical trials: Child Allergy
Bronchial Asthma
Salbutamol Administration by Nebulizer Versus Metered Dose Inhaler With Spacer in Asthma in Children
Asthma is a problem that affects many children and affects their physical health in addition to having a social and financial burden on individuals, families and healthcare systems.
- Trial name
- NCT03816267
- Testing
- Nebulizer, Salbutamol, Metered dose inhaler and spacer
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Cow Milk Allergy
The Effect of Early Cow's Milk Elimination Diet on the Growth Pattern
This study aimed to survey the growth of children who were on elimination diet due to cow milk allergy in Turkey. 0-5 year aged children diagnosed with cow's milk allergy (CMA) and healthy age-sex-matched children as the control…
- Trial name
- NCT05038995
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Atopic Dermatitis
Pre-SunBeam TEWL AUC
Transepidermal Water Loss (TEWL) measurements are a valuable tool to determine the integrity of a person's skin barrier. In patients with skin conditions, like atopic dermatitis, skin barrier can be disrupted or weakened, leading…
- Trial name
- NCT04226092
- Testing
- GPSkin Barrier Pro, Aquaflux AF200
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Asthma
A Study to Determine the Effect of Montelukast Sodium as an Episode Modifier in the Treatment of Infrequent Episodic Asthma in Children (0476-165)
A 53-week study to determine the effect of montelukast sodium when given to children (with infrequent episodic asthma) at the earliest symptoms of an acute episode of asthma.
- Trial name
- NCT00140881
- Testing
- MK0476; montelukast sodium
- Volunteers
- 220 people
- Sponsor
- Organon and Co
Asthma, Lung Diseases
Immune Dysregulation in Children and Adults With Asthma
To immunize both normal and asthmatic subjects with a neoantigen, keyhole limpet hemocyanin (KLH) and observe the type of antibody and T cell response that develops.
- Trial name
- NCT00135681
- Testing
- nedocromil budesonide
- Sponsor
- University of New Mexico
Dermatitis, Atopic
Pimecrolimus Cream 1% Plus Topical Corticosteroid in Patients (2-17 Years of Age) With Severe Atopic Dermatitis
Atopic dermatitis, also called eczema, is characterized by redness, papulation (skin elevation) and pruritus (skin itching). The active ingredient of pimecrolimus inhibits the T-cell activation.
- Trial name
- NCT00121381
- Testing
- Pimecrolimus plus topical corticosteroid (TCS)
- Where
- 13 sites in United States
- Volunteers
- 400 people
- Sponsor
- Novartis
Asthma, Acute Asthma
Effect of Addition of Single Dose of Oral Montelukast to Standard Treatment in Acute Asthma in Preschool Children.
The purpose of this study is to determine if adding single dose of oral montelukast to the standard treatment of systemic glucocorticoids plus short acting beta-2 agonist for treatment of acute wheezing provide additional…
- Trial name
- NCT01304901
- Testing
- montelukast 4 mg granule
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kecioren Education and Training Hospital
Food Allergy
Improving Nutrient Intake and Growth in Children With Multiple Food Allergies
Hypothesis 1: Food allergies are associated with poor growth which can be corrected with nutrition intervention. More than 10% of children with multiple food allergies will have a weight-for-age z-score less than - 2 at…
- Trial name
- NCT01571830
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Medical College of Wisconsin
Asthma, Lung Diseases
Randomized Trial to Reduce Environmental Tobacco Smoke in Children With Asthma
The purpose of this study is to test the effects of reducing indoor environmental tobacco smoke (ETS) on unscheduled asthma visits, asthma symptoms, airway inflammation, and exposure to tobacco smoke measured using air nicotine…
- Trial name
- NCT00006565
- Testing
- HEPA Air Cleaner
- Volunteers
- 225 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Food Allergy, Cow's Milk Protein Allergy
GOAt Milk Formula-based Ladder Versus Cow's Milk Ladder
Children with immunoglobulin E (IgE)-mediated cow's milk allergy (CMA) who react to small amounts of baked cow's milk may require prolonged elimination.
- Conditions
- Food Allergy, Cow's Milk Protein Allergy, Cow's Milk Allergy
- Trial name
- GOAL (NCT07795957)
- Testing
- oral food challenge (OFC)
- Where
- 2 sites in Poland
- Volunteers
- 92 people
- Sponsor
- Medical University of Warsaw
Burn Injury
Amino Acid Supplementation in Recovery From Severe Burns
Exercise during recovery is now Standard of Care at Shriners Hospital for Children Galveston, since positive effects of exercise training were found on lean body mass and recovery after burns.
- Trial name
- ExAA (NCT01618630)
- Testing
- EAA Supplementation + Exercise Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Asthma
Bronchodilator Effect of CHF1535 pMDI Versus Free Combination of Beclometasone Plus Formoterol pMDI in Asthmatic Children
The purpose of this clinical study is to compare the improvement in breathing of single administration of CHF 1535 50/6 pMDI (fixed combination of a corticosteroid drug beclomethasone 50 µg + formoterol 6 µg/puff, 2 inhalations…
- Trial name
- PAED3 (NCT01584492)
- Testing
- beclomethasone+formoterol 50/6 (1 inhalation), CHF 1535 50/6 (2 inhalations), CHF 1535 50/6 (4 inhalations)
- Where
- 2 sites in Poland, Ukraine
- Volunteers
- 59 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Epilepsy in Children, Pharmaco-Resistant Epilepsy
Comparison of Microbiome Composition and Biomarkers in Pharmaco Resistant and Pharmaco-Sensitive Epilepsy
The purpose of this study is to determine stool microbiome composition and biomarkers that are differentially abundant and those that are associated with response to treatment (eg, anticonvulsant drugs).
- Trial name
- NCT04308252
- Where
- United States
- Sponsor
- Senda Biosciences
Allergic Rhinitis, Upper Respiratory Infection
Study Evaluating the Pharmacokinetics of Doxylamine Succinate in Children
The primary goal of this study is to characterize the pharmacokinetics of doxylamine succinate in children ages 2 to < 18 years.
- Trial name
- NCT00796315
- Testing
- Doxylamine Succinate USP
- Where
- 6 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Food Allergy in Children
Determine Immunoglobulin G4 (IgG4) Standards for Cow's Milk and Egg in Different Populations of Allergic and Non-allergic Children
The study objectives are : Determine standards of plasma levels of casein-specific immunoglobulin G4 (IgG4) and egg-specific immunoglobulin G4 (IgG4) as a function of age, in non-allergic children, in allergic children, and in…
- Trial name
- IgG4 (NCT03776474)
- Testing
- Blood collection
- Where
- France
- Volunteers
- 135 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma in Children
Study on Hospitalization of Children With Bronchial Asthma
Bronchial asthma is the most common chronic respiratory disease in children. At present, more attention has been paid to the treatment of airway inflammation and smooth muscle spasm, while the related research on the risk factors…
- Trial name
- NCT05800379
- Where
- China
- Volunteers
- 470 people
- Sponsor
- Beijing Children's Hospital
Asthma, Asthma in Children
Effectiveness of a Mobile Health Intervention in Improving the Technique of Inhaled Medications Among Children With Asthma
In this trial, the investigators aim to determine if a new mobile health intervention (BreatheSuite) can increase inhaler technique and adherence amongst participants aged 10-18.
- Trial name
- NCT03615248
- Testing
- BreatheSuite
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Memorial University of Newfoundland
Asthma
Usefulness of Exhaled Breath Condensate for Evaluation of Markers of Airway Inflammation in Children With Asthma
Exhaled breath condensate (EBC) has emerged as a novel noninvasive technique for assessment of airway inflammation, and it provides information on airway lining fluid composition.
- Trial name
- NCT00961155
- Testing
- cyklezonid, montelukast sodium, formoterol 12 mcg twice daily
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis
Tyrosine Allergoid Paediatric and Adult Study
The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial…
- Conditions
- Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis, Allergic Asthma
- Trial name
- NCT05186025
- Testing
- MATA trees or MATA grass
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- Allergy Therapeutics
Growth & Development, Obesity
Effects of Infant Egg Consumption on Child Health and Cognition Development
The objective of this study is to examine how infant egg consumption (age of introduction and frequency of intake) influences physical growth, obesity, cardio-metabolic health, risk of food allergy, and cognition development in…
- Conditions
- Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome
- Trial name
- NCT04345185
- Testing
- Infant egg consumption (i.e., age of introduction and frequency of intake)
- Where
- United States
- Volunteers
- 5,374 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
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