Clinical trials: Child Development Disorders, Pervasive
Autism Spectrum Disorder
WMT for Autism Spectrum Disorder (ASD)
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD…
- Trial name
- NCT06030752
- Testing
- Washed Microbiota Transplantation
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Fragile X Syndrome
A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome
The purpose of this study is to determine whether NNZ-2566 is safe and well tolerated in the treatment of Fragile X Syndrome in adolescent and adult males.
- Trial name
- NCT01894958
- Testing
- NNZ-2566
- Where
- 17 sites in United States
- Volunteers
- 72 people
- Sponsor
- Neuren Pharmaceuticals Limited
Autism Spectrum Disorder
Social Motivation Intervention for Children With Autism Spectrum Disorder: Improving Peer Initiation
The purpose of this study is to investigate whether a social initiation motivation intervention (SIMI) focused on training children with ASD to initiate to peers during structured play activities will result in more frequent…
- Trial name
- NCT02360449
- Testing
- Social Initiation Motivation Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorders
Intranasal Oxytocin and Learning in Autism
The main objective of this study is to determine the safety and therapeutic potential of intranasal oxytocin in children and adolescents with autism spectrum disorder (ASD) when paired with a computer game intervention that is…
- Trial name
- NCT01417026
- Testing
- Intranasal Oxytocin (Trade name: Syntocinon)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Robert Schultz
Autism Spectrum Disorder
Food Selectivity Protocol for Children With Autism Spectrum Disorders
Food selectivity is a common challenge among children with Autism Spectrum Disorder (ASD), with significant impacts on their nutrition and well-being.
- Trial name
- NCT06179940
- Testing
- Pairwise food selectivity protocol, Individual food selectivity protocol
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Depressive Disorder
Feasibility, Acceptability, and Preliminary Effectiveness of Cognitive Behavioral Therapy for Depression in Autistic Youth in Clinical Settings
The goal of this clinical trial is to learn if Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY) can improve depressive symptoms and related mechanisms in autistic youth aged 11-17 years with depression…
- Conditions
- Autism Spectrum Disorder, Depressive Disorder, Anxiety Disorders
- Trial name
- CBT-DAY (NCT07755137)
- Testing
- CBT-DAY (Cognitive Behavioral Therapy for Depression in Autistic Youth), Treatment-as-Usual (TAU)
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Children's Hospital Los Angeles
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Autism
Risperidone Treatment In Children With Autism Spectrum Disorder And High Levels Of Repetitive Behavior
The proposed study attempts to deepen our understanding of repetitive behaviors in autism spectrum disorders (ASD) and its treatment by examining the changes in key neural circuits associated with risperidone treatment using…
- Trial name
- ProjectV (NCT01171937)
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder
Esketamine and Propofol for Children With Autism Spectrum Disorder Undergoing Colonoscopy
The purpose of this study is to examine the dose-response relationship of esketamine in combination with propofol for children with Autism Spectrum Disorder undering colonoscopy.
- Trial name
- NCT05951465
- Testing
- Esketamine, Propofol
- Where
- China
- Volunteers
- 46 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Autism Spectrum Disorder (ASD), Neurodevelopmental Disorders
Telepsychiatry in Children: Diagnostic Evaluation of Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder recognized as a major national cause in 2012. The French Autism Plan 2018-2022 emphasizes early diagnosis and intervention for better cognitive and behavioral…
- Trial name
- TELE-TSA (NCT06622395)
- Testing
- Remote diagnosys
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier St Anne
Autism
Interactive Massage Intervention in Toddlers With Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a 3-month maternal interactive massage intervention in toddlers aged 18-24 months with autism spectrum disorder (ASD).
- Trial name
- IMI-ASD (NCT07876245)
- Testing
- Maternal Interactive Massage, Behavioral
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder
A Virtual Dental Office Experience for Children With Autism Spectrum Disorder
The objective of this study is to evaluate the effectiveness of virtual reality (360° video) compared to a social story for reducing pre-visit dental anxiety for children with autism spectrum disorder (ASD) improve the dental…
- Trial name
- NCT05196230
- Testing
- Control Condition (Social Story), Experimental Condition (360° Video)
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
Pivotal Response Treatment (PRT) Telemedicine
The purpose of this study is to evaluate the application of a modified version of PRT designed specifically as a parent-training model via telemedicine, with the goal of increasing access to empirically validated care.
- Trial name
- PRT (NCT03045263)
- Testing
- Pivotal Response Treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Yale University
Autism Spectrum Disorder
Expediting Access to Services for Equity
The goal of this clinical trial is to assess whether telehealth-based Family Navigation (FN) expedites enrollment (e.g., reduces time in days) in community-based autism intervention for Black toddlers under the age of 4 after…
- Trial name
- EASE (NCT06291246)
- Testing
- Virtual Family Navigation, Educational Materials
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorders
Effectiveness and Mechanism of Online Peer Companion Intervention on Children With Autism Spectrum Disorders
The goal of this interventional study was to examine the effectiveness and mechanism of online peer companion intervention (OPCI) on the social abilities and mental health of ASD children.
- Trial name
- NCT06147141
- Testing
- Online Peer Companion Intervention, Wait-List
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University
Autism, Autism Spectrum Disorder (ASD)
Evaluation of the Social ABCs in Israel
The goal of this study is to evaluate the effectiveness of the Social ABCs program for young autistic children and their parents. The study will also explore predictors of treatment success and child outcomes.
- Trial name
- NCT07025603
- Testing
- The social ABCs
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Hebrew University of Jerusalem
Autism Spectrum Disorder, Sleep Disturbance
Telehealth Delivery of Treatment for Sleep Disturbances in Young Children With Autism Spectrum Disorder
Study Design: Ninety children with Autism Spectrum Disorder (ASD), between the ages of 2 to less than 7 years, and their parents will be recruited for this 10 week randomized clinical trial.
- Trial name
- NCT03668873
- Testing
- Sleep Parent Training, Sleep Parent Education
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- The Cleveland Clinic
Child Development Disorders, Pervasive
Risperidone Pharmacokinetics in Children With Pervasive Developmental Disorder (PDD)
The purpose of this research is to study the pharmacokinetics of risperidone in a group of pediatric patients with Pervasive Developmental Disorder (PDD).
- Trial name
- NCT00147394
- Testing
- Risperidone
- Where
- 5 sites in United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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