Clinical trials: Child Growth
Aflatoxin Ingestion
Mycotoxin Mitigation Trial
Multiple observational studies show an association between fetal and post-natal aflatoxin exposure and reduced linear growth. However, the effects of confounding factors such as socio-economic status, food insecurity and nutrient…
- Trial name
- MMT (NCT03940547)
- Testing
- Provision of flour, Promotion of flour
- Where
- Tanzania
- Volunteers
- 2,842 people
- Sponsor
- Cornell University
Malnourished Children, Stunting of Growth
Comprehensive Nutritional Support for Children in Zambia (ZamCNC) - A Pilot Investigation
In a recently completed intervention study, more than 50% of children in Lusaka were found to be stunted by age two, even when nutritional supplements were provided.
- Trial name
- ZamCnC (NCT07153913)
- Testing
- Intensive growth support
- Where
- Zambia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Günther Fink
Lead Poisoning
Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children
OBJECTIVES: Compare growth of lead-poisoned children receiving succimer (dimercaptosuccinic acid; DMSA) plus standard treatment to those receiving standard treatment only.
- Trial name
- NCT00004838
- Testing
- succimer
- Volunteers
- 175 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Loss of Chromosome 18q, Growth Hormone Deficiency
Growth Hormone and Chromosome 18q- and Abnormal Growth
We, the investigators at the University of Texas Health Science Center at San Antonio, want to learn if height and IQ (intelligence quotient) scores are improved by growth hormone (GH) treatment in children with chromosome 18…
- Trial name
- NCT00134420
- Testing
- Nutropin AQ, Arginine and Clonidine Stimulation Testing, Growth Factors Laboratory Testing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Child Nutrition, Stunting
Impact Evaluation of a Social Franchise Model for Improving Infant and Young Child Feeding and Child Nutrition in Vietnam
Alive \& Thrive is an initiative that aims to improve infant and young child feeding practices and reduce childhood stunting. In Vietnam, Alive \& Thrive's primary intervention is implemented through a social franchise linked…
- Conditions
- Child Nutrition, Stunting, Exclusive Breastfeeding, Complementary Feeding
- Trial name
- NCT01676623
- Testing
- Standard government health services, Alive & Thrive IYCF franchise services, Mass media campaign
- Where
- Vietnam
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Fractures in Children, Apophysitis
Total Genotype Score, Growth, Maturation and Loading Exposure as Risk Factors for Injury in Elite Male Youth Football
A total genotype risk score was generated based on the findings of previous research for non-contact injury, non-contact muscle injury, tendon injury, ligament injury, fracture injury and apophysitis injury.
- Conditions
- Fractures in Children, Apophysitis, Muscle Strain, Ligament Injury
- Trial name
- NCT05220969
- Testing
- Total Genotype Risk Score
- Where
- 2 sites in United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Growth Hormone Deficiency
Phase 2 Study of LUM-201 in Children With Growth Hormone Deficiency (OraGrowtH210 Trial)
This is a multi-national trial. The goals of the trial are to study LUM-201 as a possible treatment for Pediatric Growth Hormone Deficiency (PGHD) and investigate a predictive enrichment marker (PEM) strategy to select subjects…
- Trial name
- OraGrowtH210 (NCT04614337)
- Testing
- LUM-201, rhGH Norditropin® pen (34 µg/kg)
- Where
- 43 sites in United States, Australia and 4 more
- Volunteers
- 104 people
- Sponsor
- Lumos Pharma
Growth & Development, Child Development
Resident Surveillance of Pediatric Patient Developmental Status at the Two Month Preventive Care Visit
The purpose of this study is to evaluate the efficacy of individualized performance feedback coupled with an educational module in improving resident performance of the physical and developmental examination component of…
- Conditions
- Growth & Development, Child Development, Internship and Residency, Education, Medical
- Trial name
- NCT00465361
- Testing
- performance feedback with an educational module
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Children's Mercy Hospital Kansas City
Hypochondroplasia
An Interventional Study of Infigratinib in Children With Hypochondroplasia
ACCEL2/3 is a Phase 2/3 study. The purpose of the Phase 2 portion of the study (ACCEL2/3) is to evaluate the efficacy and safety of infigratinib in children with hypochondroplasia (HCH) receiving infigratinib at one of two doses…
- Trial name
- HCH (NCT06873035)
- Testing
- infigratinib 0.128 mg/kg/day, infigratinib 0.25 mg/kg/day
- Where
- 24 sites in United States, Australia and 8 more
- Volunteers
- 24 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Malnutrition, Stunting of Growth
Efficacy of Caterpillar Cereal for Complementary Feeding in the Democratic Republic of Congo
Two in every three infants in rural areas of the Democratic Republic of Congo (DRC) suffer from stunting of linear growth by 12 months of age.
- Conditions
- Malnutrition, Stunting of Growth, Iron Deficiency Anemia, Neurodevelopmental Impairment
- Trial name
- CAT02 (NCT01282788)
- Testing
- Caterpillar Cereal
- Where
- Republic of the Congo
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malnutrition, Child, Growth; Stunting, Nutritional
Samaki Salama: Small-scale Fisheries for Healthy Nutrition and Ecosystems
The purpose of this study is to test the effectiveness of a bundled intervention to address malnutrition and its intersections with nutrition security and fisheries sustainability in Kilifi, Kenya.
- Trial name
- NCT05254444
- Testing
- Social marketing, social marketing + gear modification
- Where
- Kenya
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Idiopathic Short Stature
A 4 Year Combination Therapy of Growth Hormone and (GnRH) Agonist in Children With a Short Predicted Height
Estrogens are responsible for the disappearance of growth cartilage in the long bones at the end of the pubertal growth spurt both in boys and in girls.
- Trial name
- ZomaTrip (NCT00840944)
- Testing
- somatropin, triptorelin
- Where
- 6 sites in Belgium
- Volunteers
- 44 people
- Sponsor
- Belgian Study Group for Pediatric Endocrinology
Nutrition Disorder, Child, Nutrition Disorders in Adolescence
Health and Nutrition Survey on Shenzhen Children
1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors.
- Conditions
- Nutrition Disorder, Child, Nutrition Disorders in Adolescence, Nutritional Deficiency, Nutrition, Healthy
- Trial name
- NCT05244785
- Where
- China
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Nutritional Stunting
Development of Appetite Measuring Tool and Appetite Status of Stunted Children
This study will provide a tool for researchers to measure important outcomes in relation to trial of intervention to reduce or prevent stunting.
- Trial name
- NCT02839148
- Testing
- Food supplementation
- Where
- Bangladesh
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Measles Infection
Additional Measles Vaccine at 4 Months of Age
Overall objective: To conduct a randomised controlled trial (RCT) to examine whether an early two-dose measles vaccination (MV) strategy at 4 and 9 months will reduce child mortality compared with the WHO strategy of one dose of…
- Trial name
- NCT01486355
- Testing
- Measles vaccine
- Where
- Guinea-Bissau
- Sponsor
- Bandim Health Project
Growth Disorders, Growth Failure
Randomized Clinical Trial of Two Different Initial Growth Hormone Doses in Children
A prospective, randomized, open-label single-blinded study of 50 subjects with growth hormone deficiency, ages 5 to 15 years in which 25 subjects will initiate rhGH therapy at 0.3mg/kg/week and the remaining 25 subjects will…
- Conditions
- Growth Disorders, Growth Failure, Growth Hormone Treatment, Growth
- Trial name
- NCT06103513
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Diarrhea
Slow Versus Rapid Rehydration of Severely Malnourished Children
The recommendation for correction of dehydration of severely malnourished children with diarrhoea includes oral rehydration and if parenteral rehydration is necessary (for example, in severe dehydration) to infuse intravenous…
- Trial name
- NCT02216708
- Testing
- Rapid dehydration, Slow rehydration
- Where
- Bangladesh
- Volunteers
- 208 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Chronic Disease
Effects of Delayed Growth on the Quality of Life of Children Treated for a Chronic Disease and Quality of Life Study of Their Parents and Siblings
Chronic childhood diseases have sometimes strong repercussions on the everyday life of patients and their families, because of strict daily treatment regimens, physical limitation or effects on social life for instance In…
- Trial name
- CROQUIE (NCT04733391)
- Testing
- Quality of life questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Child Development
LIFE Child (LIFE Leipzig Research Centre for Civilization Diseases)
The Leipzig Research Centre for Civilization Diseases (LIFE) Child Study is a prospective longitudinal population-based study with a life course approach to health and disease.
- Trial name
- NCT02550236
- Where
- Germany
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Growth Disorders
Growth Chart Parameters, Risk Factors
comparison between growth chart parameters and different risk factors which can cause abnormal growth chart parameter
- Trial name
- NCT05841264
- Testing
- good feeding, cleaning
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assiut University