Clinical trials: Childhood Depression
Depression, Parent-Child Relations
Parent Encouragement And Coaching of Happiness in Youth
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1.
- Trial name
- PEACHY (NCT06725160)
- Testing
- Parent Coaching, Active Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Substance Abuse, Juvenile Delinquency
The Community Youth Development Study: A Test of Communities That Care
The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that were trained to use the CTC system improved public…
- Conditions
- Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior
- Trial name
- CYDS IV (NCT01088542)
- Testing
- Communities That Care
- Where
- United States
- Volunteers
- 52,323 people, healthy volunteers welcome
- Sponsor
- University of Washington
Adolescent Cancer Survivors, Childhood Cancer Survivors
IMpact of Mind-body Therapies (HYpnosis and Relaxation) on Anxiety in Children, Adolescents and Young Adults Who Had Been Treated in ONcology. Multicenter Study.
In France today, it is estimated that one in 850 people aged between 20 and 45 has been cured of cancer in childhood. Some descriptive studies have established that cancer diagnosis and treatment can affect psychological health…
- Conditions
- Adolescent Cancer Survivors, Childhood Cancer Survivors, Anxiety
- Trial name
- HARMONY-Impact (NCT07380672)
- Testing
- 10 mind-body therapy sessions (hypnosis or relaxation, depending on the patient's choice), 9 sessions of standard psychological care
- Where
- 5 sites in France
- Volunteers
- 558 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
Inflammatory Bowel Disease
Integrated Behavioral Health Innovations in Childhood Chronic Illness Care Delivery Systems
Study design: At baseline, all adolescents and young adults with IBD ages 12-21 years will be screened for anxiety and depression symptoms using the PHQ-9 and the Screen for Child Anxiety Related Disorders (SCARED) during a…
- Trial name
- NCT02740309
- Testing
- Integrated Brief Behavior Therapy (IBBT) Intervention, Treatment as usual
- Where
- United States
- Sponsor
- NYU Langone Health
Depression
Omega-3 and Therapy Study for Depression
Childhood depression warrants treatment research; including pharmacological and psychotherapeutic interventions. A recent study found fluoxetine to be the only medication with empirical support for decreasing depression in…
- Trial name
- OATS (NCT01341925)
- Testing
- Omega-3 Supplementation, Psychoeducational Psychotherapy (PEP)
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- L. Eugene Arnold
Cancer
DST in Reducing Depressive Symptoms, Enhancing Self-esteem, and Promoting Quality of Life Among CCSs
This study aims to examine the effectiveness of Digital storytelling (DST) in reducing depressive symptoms, enhancing self-esteem, and promoting quality of life among Chinese survivors of childhood cancer.
- Trial name
- NCT07052110
- Testing
- Digital storytelling
- Where
- Hong Kong
- Volunteers
- 248 people
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Change, Growth; Stunting, Nutritional
The Sugira Muryango Longitudinal & Spillover Study
The Early Childhood version of Sugira Muryango is a family-based, home-visiting intervention targeted at early childhood development and implemented with families living in extreme poverty in three districts of Rwanda.
- Conditions
- Cognitive Change, Growth; Stunting, Nutritional, Language, Depression
- Trial name
- NCT05405400
- Where
- 3 sites in Rwanda
- Volunteers
- 2,932 people, healthy volunteers welcome
- Sponsor
- Boston College
Anaesthesia, Neurodevelopment
Impact of Perinatal Anaesthesia and Analgesia on Neurocognitive Outcomes in Early Childhood
This study aims to determine the impact of perinatal exposure to anaesthesia and analgesia on neurocognitive outcomes in early childhood by analyzing neurocognitive data already obtained from the local prospective observational…
- Trial name
- PANO (NCT02184780)
- Where
- Singapore
- Volunteers
- 468 people
- Sponsor
- KK Women's and Children's Hospital
Depression
Activating and Connecting Teens (ACT) Study
National data indicate over 650,000 children and adolescents are exposed to physical, sexual, or emotional abuse or physical or emotional neglect each year.
- Trial name
- ACT (NCT03438656)
- Testing
- Behavioral Activation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Washington
Social Withdrawal of Childhood or Adolescence, Preterm Infant
The Effect of a Neonatologist's Standardized Guidance Intervention on Preterm Infants With Relational Withdrawal.
The objective of this project is to determine the effect of the verbal intervention on the decrease in sustained social withdrawal in late and moderately late preterm infants.
- Trial name
- NCT03212547
- Testing
- Verbal Intervention
- Where
- 2 sites in Chile
- Volunteers
- 110 people
- Sponsor
- Clinica Alemana de Santiago
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Depression, Anxiety
Short-term, Long-term and Cost-effectiveness of Treating Depression and Anxiety Disorders in Children and Adolescents
The current study will evaluate and compare the effectiveness of cognitive-behavioral and psychodynamic therapy. Therefore 420 children and adolescents (ages 8-16 years) with depression and/or anxiety disorder will be randomly…
- Trial name
- NCT03333239
- Testing
- psychodynamic psychotherapy, cognitive behavioral psychotherapy, psychodynamic family intervention
- Volunteers
- 420 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Childhood Depression, Childhood Anxiety
Integrative Coping Group for Children
The purpose of this study is to examine whether an integrative group-based intervention will help children experiencing psychological and physical distress.
- Conditions
- Childhood Depression, Childhood Anxiety, Pediatric Pain, Migraines
- Trial name
- ToPSY (NCT01813669)
- Testing
- Integrative Coping Group
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Duke University
Stunting, Obesity
Effects of Probiotics and Calcium Supplementation on Growth, Development, and Metabolic Parameters
Stunting is still a major problem in developing countries, including Indonesia, and has been associated with impaired development. Stunted children have also a higher risk of metabolic syndrome in adulthood.
- Conditions
- Stunting, Obesity, Cognitive Function 1, Social, Depression
- Trial name
- PROBIOCAL (NCT04046289)
- Testing
- Low Calcium Milk, Regular Calcium Milk, Probiotic 1
- Where
- Indonesia
- Volunteers
- 238 people
- Sponsor
- Universitas Indonesia
Adolescent Development, Stunting
The Nash-wo-Numa (Childhood Growth & Development) Study
The proposed study will be a cross-sectional study in the District of Matiari, Pakistan. Children ages 9-15 years will be identified from a Matiari District household census scheduled being conducted from December 2016- to May…
- Conditions
- Adolescent Development, Stunting, Depression, Micronutrient Deficiency
- Trial name
- NCT03647553
- Where
- Pakistan
- Volunteers
- 1,385 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Conduct Problems, Anxiety Symptoms
Testing the Effectiveness of Supportive Parents - Coping Kids
The aim of this clinical trial is to test the effectiveness of the parent training intervention Supportive Parents - Coping Kids (SPARCK) for prevention of childhood mental health problems.
- Conditions
- Conduct Problems, Anxiety Symptoms, Depressive Symptoms
- Trial name
- SPARCK (NCT05800522)
- Testing
- Behavioral parent or child directed intervention, Supportive Parents - Coping Kids
- Where
- Norway
- Volunteers
- 252 people
- Sponsor
- Norwegian Center for Child Behavioral Development
Anxiety, Anxiety Disorders
Transdiagnostic, Cognitive and Behavioral Intervention for in School-aged Children With Emotional and Behavioral Disturbances
Background Impairing emotional and behavioural problems are common in children and adolescents and mark a three-fold increased risk of mental disorder in young adulthood.
- Conditions
- Anxiety, Anxiety Disorders, Depressive Symptoms, Depressive Disorders
- Trial name
- MindMyMind RCT (NCT03535805)
- Testing
- Mind My Mind (MMM), Treatment as Usual (TAU)
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Depression
The Omega-3 Fatty Acid Paediatric Depression Trial
This study investigates the therapeutic efficacy and safety of omega-3 fatty acids rich in eicosapentaenoic acid / docosahexaenoic acid in pediatric depression in a nine months double-blind multi-centre study in 220 children and…
- Trial name
- Omega-3-pMDD (NCT03167307)
- Testing
- Omega 3 fatty acid
- Where
- 7 sites in Switzerland
- Volunteers
- 257 people
- Sponsor
- Gregor Berger
Anxiety, Depression
Detecting and Evaluating Childhood and Anxiety and Depression Effectively in Subspecialties
The DECADES trial seeks to determine the comparative effectiveness of specialist-centered management of anxiety and depression vs.
- Trial name
- DECADES (NCT02773706)
- Testing
- Automated Psychology Services, Notification of Subspecialist
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University