Clinical trials: Choice Behavior
Head Injury
Shared Decision Making in Parents of Children With Head Trauma: Head CT Choice
The investigators will test the impact of a decision aid, Head CT Choice, to determine if its use improves parents' knowledge and engagement in decision making and safely decreases healthcare utilization in children presenting to…
- Trial name
- NCT02063087
- Testing
- Head CT Decision Aid
- Where
- 7 sites in United States
- Volunteers
- 971 people
- Sponsor
- Mayo Clinic
Pediatric Cardiac Surgery
Influence of Inotropic Choice on Morbidity and Mortality in Complex Pediatric Heart Surgery
Our study is based on the observation that management of the cardiopulmonary by-pass withdrawal in pediatric heart surgery is quite variable between medical teams.
- Trial name
- CHUBpedCSino (NCT04380181)
- Testing
- dobu
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- Brugmann University Hospital
Consumer Behavior
Decoding the Interplay of Front-of-Pack Labels, Price, and Consumer Perceptions: Impact on Food Choices in Korea and Singapore
The global epidemic of obesity and chronic diseases has led to widespread use of front-of-package (FOP) nutrition labels. While existing research has established a link between FOP labels and consumer choices, the interplay…
- Trial name
- NCT07186270
- Testing
- Positively framed FOP labels (present versus absent) x Price (high versus low), Graded FOP labels (no label vs. high rating (grade A) vs. low rating (grade D)) x Price (average vs. premium)
- Volunteers
- 1,000 people
- Sponsor
- Duke-NUS Graduate Medical School
Ras/MAPK Pathway Vascular Anomalies, Vascular Anomalies
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs
The purpose of this study is to assess the effectiveness and safety of Trametinib (the "Study Drug") in patients with Ras/MAPK pathway driven vascular anomalies (VA). Trametinib has been approved by the U.S.
- Conditions
- Ras/MAPK Pathway Vascular Anomalies, Vascular Anomalies, Vascular Anomaly
- Trial name
- VATCH (NCT07549646)
- Testing
- Trametinib
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Hospital of Philadelphia
HIV Infections
Fuzeon (Enfuvirtide) Early Access Program for Patients With HIV-1 Infection
This study will determine the safety and tolerability of Fuzeon (enfuvirtide) used together with other treatments for HIV infection in patients with advanced HIV disease. Fuzeon is an antiretroviral drug.
- Trial name
- NCT00050856
- Testing
- Enfuvirtide T/20/Ro 29,9800, HIV-1 Infusion Inhibitor
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Metastatic, Locally Advanced or Unresectable Soft Tissue Sarcoma
Phase 3 Study to Treat Patients With Soft Tissue Sarcomas
The purpose of this study is to determine the efficacy and safety of aldoxorubicin in subjects with metastatic, locally advanced, or unresectable soft tissue sarcomas.
- Trial name
- NCT02049905
- Testing
- Aldoxorubicin, Investigator's Choice Treatment (Darcabazine, Pazopanib, Gemcitabine + Docetaxel, Doxorubicin, Ifosfamide)
- Where
- 74 sites in United States, Australia and 11 more
- Volunteers
- 433 people
- Sponsor
- ImmunityBio, Inc.
Thymic Epithelial Tumor
Intrathoracic Chemotherapy for TETs With Pleural Spread or Recurrence
Hyperthermic intrathoracic chemotherapy (HITOC) offers an additional treatment option for malignant pleural tumors after surgical cytoreduction.
- Trial name
- CHOICE (NCT05446935)
- Testing
- HITOC
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Shanghai Zhongshan Hospital
Substance-related Disorders
Project CHOICE: Efficacy Testing of CHOICE and CHOICE+Normative Feedback Interventions
This study will use a pilot test format to examine the efficacy of a brief Motivational Interviewing (MI) intervention developed by the investigator Dr.
- Trial name
- CHOICE (NCT02083523)
- Testing
- Motivational Interview with Normative Feedback, Motivational Interview
- Volunteers
- 48 people
- Sponsor
- University of Illinois at Urbana-Champaign
Choice Behavior
DÉCISION+, a Continuous Professional Development Program to Improve Optimal Drug Prescription : a Feasibility Study
The objective of this project is to evaluate the feasibility of a larger randomized trial of the efficacy of DECISION+, a continuous professional development program integrating multiple components, to promote shared decision…
- Trial name
- NCT00354315
- Testing
- Continuous medical education (CME)
- Where
- Canada
- Volunteers
- 642 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Polycystic Ovary Syndrome
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
This study aimed to understand whether metformin therapy can improve insulin resistance in adolescent PCOS patients, both during treatment and after discontinuation, and to evaluate its action on the hormonal and metabolic…
- Trial name
- NCT06015594
- Testing
- Metformin
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Teen Pregnancy Prevention, Contraceptive Usage
Federal Evaluation of Selected Programs for Expectant and Parenting Youth
Under contract to the U.S. Department of Health and Human Services (DHHS), Mathematica Policy Research is conducting an impact study of Healthy Families Healthy Futures in Houston, Texas for a Federal Evaluation of Programs for…
- Trial name
- PEPY (NCT03419728)
- Testing
- Healthy Families, Healthy Futures
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Mathematica Policy Research, Inc.
Pectus Excavatum
Lung Ultrasound for the Postoperative Diagnosis of Pneumothorax in Children
This study will be conducted to determine the advantages and limitations of sonography compared with chest radiography, in the detection of post procedure iatrogenic pneumothorax in patients underwent to Pectus Excavatum (PE)…
- Trial name
- ECO_NUSS (NCT03073616)
- Testing
- Lung ultrasound
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Nicola Disma, MD
Unintended Pregnancy, Contraception
Contraceptive Choice Center
The Contraceptive Choice Center will use an innovative-model of contraceptive care which was developed as a part of the Contraceptive CHOICE Project (CHOICE).
- Conditions
- Unintended Pregnancy, Contraception, Family Planning
- Trial name
- C3 (NCT02633631)
- Where
- United States
- Volunteers
- 2,664 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Laparotomy
PDS vs Polyamide for Midline Abdominal Closure
Within the last decade the customary trend of using non absorbable sutures has changed, with numerous studies and meta-analyses advocating the use of slowly absorbable sutures, claiming comparable wound strength with…
- Trial name
- PPMAC (NCT00514566)
- Testing
- Suture for midline abdominal closure
- Where
- India
- Volunteers
- 64 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma
Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)
This phase II Pediatric MATCH trial studies how well olaparib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with defects in deoxyribonucleic acid (DNA) damage repair genes that have…
- Conditions
- Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma, Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma, Low Grade Glioma
- Trial name
- NCT03233204
- Testing
- Olaparib
- Where
- 113 sites in United States, Puerto Rico
- Volunteers
- 6 people
- Sponsor
- National Cancer Institute (NCI)
Emergencies, Diabetes Mellitus
Geography of ED Use and Population Health
The goal of this study is to create predictive models of emergency care and metrics for population health that can be used to analyze how events like hospital closures or disasters like Hurricane Sandy affect health care…
- Trial name
- NCT03254524
- Testing
- Statewide Planning and Research Cooperative System Database
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Healthy Subjects, Behavior, Health
Switching Mediterranean Consumers to Mediterranean Sustainable Healthy Dietary Patterns
The population from Mediterranean countries is abandoning the Mediterranean diet (MD) traditional dietary and lifestyle pattern moving to unhealthier habits because of profound cultural and socio-economic driven lifestyle…
- Conditions
- Healthy Subjects, Behavior, Health, Family
- Trial name
- NCT06057324
- Testing
- AI-based Apps, Mediterranean-based diet toolkit and activities, Healthy plant-based snacks
- Where
- Spain
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Detention Under the Mental Health Act
Advance Choice Document Implementation
Advance Choice Documents (ACDs) are statements of preferences for mental health care and treatment made when service users have capacity to do so. This is done with their care team and others as desired, e.g.
- Trial name
- ACDI (NCT07284368)
- Testing
- Advance Choice Document Implementation
- Where
- United Kingdom
- Volunteers
- 374 people
- Sponsor
- King's College London
Malignant Solid Neoplasm, Recurrent Adrenal Gland Pheochromocytoma
Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment Trial
This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have recurred or spread to other places in the body (advanced), lymphoma, or histiocytic disorders, that have a…
- Conditions
- Malignant Solid Neoplasm, Recurrent Adrenal Gland Pheochromocytoma, Recurrent Ectomesenchymoma, Recurrent Ependymoma
- Trial name
- NCT04284774
- Testing
- Tipifarnib
- Where
- 172 sites in United States, Puerto Rico
- Volunteers
- 5 people
- Sponsor
- National Cancer Institute (NCI)
Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma
Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)
This phase II Pediatric MATCH trial studies how well selumetinib sulfate works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with MAPK pathway activation mutations that have spread to…
- Conditions
- Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma, Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma, Recurrent Childhood Central Nervous System Neoplasm
- Trial name
- NCT03213691
- Testing
- Laboratory Biomarker Analysis, Selumetinib, Selumetinib Sulfate
- Where
- 110 sites in United States, Puerto Rico
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)