Clinical trials: Choice Behavior, open to volunteers
Complicated Urinary Tract Infection, Infection
Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children
Urinary tract infections (UTI) are commonly encountered in children, with 7% diagnosed with at least one UTI by the age of 19 years.
- Conditions
- Complicated Urinary Tract Infection, Infection, Pediatric Infectious Disease
- Trial name
- CHOICE UTI (NCT04876131)
- Testing
- Benzylpenicillin - single dose, Benzylpenicillin - three days, Gentamicin - single dose
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 396 people
- Sponsor
- Murdoch Childrens Research Institute
Ras/MAPK Pathway Vascular Anomalies, Vascular Anomalies
24VA021; VATCH Trametinib for Ras/MAPK Pathway VAs
The purpose of this study is to assess the effectiveness and safety of Trametinib (the "Study Drug") in patients with Ras/MAPK pathway driven vascular anomalies (VA). Trametinib has been approved by the U.S.
- Conditions
- Ras/MAPK Pathway Vascular Anomalies, Vascular Anomalies, Vascular Anomaly
- Trial name
- VATCH (NCT07549646)
- Testing
- Trametinib
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Children's Hospital of Philadelphia
Water, Child Nutrition
Water is K'é: Multi-level Intervention to Promote Healthy Beverage Choices Among Navajo Families
The goal of this clinical trial is to understand if a cultural intervention for Navajo families will improve healthy beverage habits, health outcomes, and family cohesion.
- Conditions
- Water, Child Nutrition, Family Dynamics, Healthy Nutrition
- Trial name
- NCT06020027
- Testing
- Water is K'é
- Where
- United States
- Volunteers
- 1,160 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Health Behavior, Wellness, Psychological
Teen Health Choices & Wellness
The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older.
- Conditions
- Health Behavior, Wellness, Psychological, Substance Use
- Trial name
- THC&W (NCT06822569)
- Testing
- Cue reactivity paradigm
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Brown University
Group 1: Carrier Care (CC) Followed by Skin-to-Skin Care (SSC) Followed by Family Choice, Group 2: Skin-to-Skin Care (SSC) Followed by Carrier Care (CC) Followed by Family Choice
Carrier Care: An Innovative Approach to Support Small Babies in the NICU
The significance of skin-to-skin care (SSC) for neonatal infants is well-documented, highlighting its benefits for both the infant and the caregiver.
- Trial name
- NCT07142564
- Testing
- Carrier Care (CC)
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Low-grade Glioma, Pediatric Low-grade Gliomas
FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration
An open-label, randomized, multi-center phase III clinical study: Aim to evaluate the efficacy and safety of FCN-159 monotherapy versus the treatment by investigator's choice in patients with pediatric low-grade glioma harboring…
- Conditions
- Low-grade Glioma, Pediatric Low-grade Gliomas, pLGG With BRAF Alteration
- Trial name
- NCT07004075
- Testing
- Luvometinib, Chemotherapeutic Agent COG-V/C Carboplatin + Vindesine, Carboplatin, Temozolomide
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Retinoblastoma, Chemotherapy Effect
Topotecan and Melphalan for Retinoblastoma
The purpose of this study is to evaluate topotecan and melphalan for retinoblastoma patients.
- Trial name
- NCT04799002
- Testing
- Topotecan, Melphalan
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Contraception Behavior, Sexual Behavior
Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
This is a prospective study involving two phases: 1) adaptation and 2) intervention, in adolescents aged 14-21 experiencing homelessness.
- Conditions
- Contraception Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- CHOICE-AYA (NCT05022134)
- Testing
- CHOICE-AYA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Rectal Neoplasms
Choice of the Optimal Treatment Strategies for Mid-low REctal Cancer
The purpose of this study is to compare the efficacy, prognosis, health economics of different treatment modalities of mid-low rectal cancer in different centers in China, and to conduct cost utility analysis (CUA) on the…
- Trial name
- COMREC (NCT05871762)
- Testing
- Registry study, no specific intervention
- Where
- China
- Volunteers
- 3,705 people
- Sponsor
- Peking Union Medical College Hospital
HIV/AIDS, HIV/AIDS Prevention
Peer-led Dynamic Choice HIV Prevention for Women: The Peer-led DCP Randomized Trial
This Hybrid Type 1 cluster randomized trial will test the Peer-led Dynamic Choice HIV Prevention (DCP) intervention compared to standard of care.
- Trial name
- NCT07787988
- Testing
- Peer-led Dynamic Choice HIV Prevention (DCP) intervention
- Where
- Uganda
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Food Preferences, Food Selection
Increasing Food Literacy in Preschoolers to Reduce Obesity Risk
The goal of this clinical trial is to examine the effects of a nutrition education program on preschool children's food literacy and food acceptance, and to examine the added influence of a healthy eating curriculum and parent…
- Conditions
- Food Preferences, Food Selection, Eating, Healthy, Obesity, Childhood
- Trial name
- NCT05977348
- Testing
- Healthy Eating Curriculum, Improving the Classroom Food and Mealtime Environment, Parent Education
- Where
- United States
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Penn State University
Long Term Care Homes, Malnutrition Elderly
CHOICE+ Quality Improvement for Long Term Care Homes
CHOICE+ is an eLearning program that empowers staff to improve the mealtime experience of long-term care (LTC) residents. This program is based on principles that align with relationship-centered care and promote resident quality…
- Conditions
- Long Term Care Homes, Malnutrition Elderly, Malnutrition Risk in Elder
- Trial name
- CHOICE+ (NCT07505407)
- Testing
- CHOICE+ virtual training program
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Waterloo
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Program Engagement, Treatment Adherence and Compliance
Choice and Autonomy in Learning Mindfulness for Pediatric Residents
This study is a pilot clinical trial designed to evaluate a flexible, online mindfulness program for pediatric residents. Medical training can be stressful, and although mindfulness programs are often offered to support…
- Conditions
- Program Engagement, Treatment Adherence and Compliance, Mindfulness, Self-Compassion
- Trial name
- CALM-PR (NCT07542769)
- Testing
- Wakeful Digital Mindfulness Program
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Unintended Pregnancy Prevention
Telemedicine for Contraceptive Counselling- An Open Randomized Controlled Trial
Protocol Summary: Sweden has high unintended pregnancy rates, increasing unmet contraceptive needs, and the highest repeat abortion rate in the European Union.
- Trial name
- Tele-prev (NCT06896539)
- Testing
- Telemedicine, Counselling in person visit
- Volunteers
- 772 people
- Sponsor
- Region Örebro County
MLD, Krabbe Disease
Longitudinal Study of Neurodegenerative Disorders
The purpose of this study is to understand the course of rare genetic disorders that affect the brain. This data is being analyzed to gain a better understanding of the progression of the rare neurodegenerative disorders and the…
- Conditions
- MLD, Krabbe Disease, ALD, MPS I
- Trial name
- NCT03333200
- Testing
- Palliative Care, Hematopoetic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Occupational Therapy Students
Intentional Relationship Model in OT Students
This study aims to examine the changes in occupational therapy interns' professional personality types and therapeutic use behaviors through an Intentional Relationship Model (IRM)-based training program.
- Trial name
- NCT07133009
- Testing
- Intentional Relationship Model (IRM) Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Attention Deficit Hyperactivity Disorder, Problem Behavior
Stimulant Effects on Disruptive Behavior
The goal of this study is to determine the effects of stimulant medication on disruptive behavior, function, preference and choice; however, it is primarily methodological and will add to current research by establishing an…
- Trial name
- NCT03420339
- Testing
- Stimulant
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Matthew J O'Brien, PhD, BCBA-D
HIV
ALIGN: A Non-randomised Study Delivering Injectable Lenacapavir for HIV Prevention Within a Pre-exposure Prophylaxis (PrEP) Choice Context in Cape Town, South Africa.
The ALIGN study will evaluate the delivery of injectable Lenacapavir (LEN), a long-acting injectable formulation for HIV pre-exposure prophylaxis (PrEP), amongst adolescents and young people (aged 15-35 years) living within the…
- Trial name
- ALIGN (NCT07390409)
- Testing
- Lenacapavir Injection, Cabotegravir (CAB) LA, Tenofovi-Emtricitabine (TDF/FTC) tablet
- Where
- South Africa
- Volunteers
- 3,700 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Ultra-Processed Food Consumption, Obesity Prevention
Sustainable and AI-Enabled Adolescents and Youth-Centred Interventions to Upgrade Food Choices and Promote Healthy, Sustainable Diets
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-supported, context-aware digital nudging intervention designed to reduce ultra-processed food consumption and improve dietary sustainability among…
- Conditions
- Ultra-Processed Food Consumption, Obesity Prevention, Dietary Behaviour, Unhealthy Diet
- Trial name
- STAY-UP (NCT07514312)
- Testing
- Artificial intelligence-supported digital nudging
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University