Clinical trials: Chronic Coronary Occlusion
Chronic Total Occlusion of Coronary Artery
CrossBoss and Hybrid Registry on Coronary Chronic Total Occlusions
The successful re-opening of a blocked coronary artery has a beneficial effect on the further clinical course (e.g. improvement of clinical symptoms, improved quality of life, increased heart function, etc.).
- Trial name
- RECHARGE (NCT02075372)
- Testing
- Data registration
- Where
- 21 sites in Belgium, France and 2 more
- Volunteers
- 1,177 people
- Sponsor
- Hasselt University
Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery
Predictors and Long-term Incidence of In-stent Restenosis After Chronic Total Occlusion Percutaneous Coronary Intervention
The goal of this clinical trial is to describe the long-term (≥ 3 years) patency of coronary artery stents following chronic total occlusion percutaneous coronary intervention (CTO PCI).
- Conditions
- Coronary Artery Disease (CAD), Chronic Total Occlusion of Coronary Artery, Chronic Total Occlusion (CTO)
- Trial name
- NCT07473596
- Testing
- chronic total occlusion percutaneous coronary intervention (CTO PCI), coronary computed tomography angiography, invasive coronary angiography
- Where
- Finland
- Volunteers
- 294 people
- Sponsor
- Lauri Mansikkaniemi
Angina Pectoris, Coronary Artery Disease
Chronic Total Coronary Occlusion Treatment Results 6 Years After Bioresorbable Scaffold Implantation
Aim of the study is to evaluate chronic total coronary occlusion treatment results 6 years after bioresorbable scaffold implantation by quantitative coronary analysis, intravascular ultrasound and optical coherence tomography.
- Conditions
- Angina Pectoris, Coronary Artery Disease, Occlusion, Coronary
- Trial name
- CTO_BVS (NCT06164977)
- Testing
- Percutaneous coronary intervention.
- Where
- Latvia
- Volunteers
- 34 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Chronic Total Occlusion of Coronary Artery
Application of Coronary Artery Chronic Total Occlusion Scoring Systems
Studying the prediction ability of different CTO scoring systems on Asian CTO PCI population with their relation to technical success and developing a newer stepwise approach depending on these CTO scoring systems for choosing…
- Trial name
- CTO-PCI (NCT05883579)
- Testing
- percutaneous coronary intervention
- Where
- Taiwan
- Volunteers
- 650 people
- Sponsor
- Assiut University
Angioplasty, Chronic Coronary Occlusion
XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study
This is a prospective, observational, single-arm, open-label, multicenter, postapproval registry study in China. The purpose of this study is to: Evaluate the continued safety and effectiveness of the XIENCE V EECSS in a cohort…
- Conditions
- Angioplasty, Chronic Coronary Occlusion, Stent Thrombosis, Vascular Disease
- Trial name
- XV CHINA SAS (NCT01249027)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
- Where
- United States
- Volunteers
- 2,605 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease, End Stage Renal Disease
Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil
Nicorandil is potentially effective to prevent cardiovascular events in patients with coronary artery disease (CAD) receiving hemodialysis.
- Trial name
- NCT01475123
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 268 people
- Sponsor
- Kumamoto University
Coronary Artery Disease, Chronic Total Occlusions
Prognostic Impact of Chronic Total Occlusions
The purpose of this study is to determine the prognostic impact of the presence of chronic total occlusions (CTO) of the coronary arteries in patients undergoing coronary angiography and PCI.
- Trial name
- NCT02084888
- Where
- Sweden
- Volunteers
- 91,154 people
- Sponsor
- Sahlgrenska University Hospital
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Angina, Chronic Coronary Occlusion
XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan
The objectives of this post-marketing surveillance, conducted in Japan, is to know the frequency, type and degree of device malfunction, to assure the safety of the medical device, and to collect information on evaluation of the…
- Conditions
- Angina, Chronic Coronary Occlusion, Stent Thrombosis, Vascular Disease
- Trial name
- NCT01086228
- Testing
- XIENCE V / PROMUS stent
- Where
- 47 sites in Japan
- Volunteers
- 2,010 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease
Stem Cell Mobilization to Treat Chest Pain and Shortness of Breath in Patients With Coronary Artery Disease
This two-part study will determine whether stem cells (primitive cells produced by the bone marrow that can develop into blood cells or other types of cells) can be pushed out into the bloodstream, relocate in the heart, and grow…
- Trial name
- NCT00043628
- Testing
- Stem Cell Mobilization
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Coronary Insufficiency, Coronary Artery Disease
Microcirculatory Status After Intravascular Lithotripsy
Due to differences in the mechanism of action, intravascular lithotripsy is likely to cause less distal embolization and microcirculatory dysfunction during plaque preparation.
- Trial name
- MARVEL (NCT05134051)
- Testing
- Shockwave® Intravascular Lithotripsy System (Shockwave Medical Inc)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Cardiac Research Institute BV
Cardiovascular Diseases, Kidney Transplant; Complications
Cardiovascular Risk Assessment For Kidney Transplantation - Utility of Computed Tomography Coronary Angiography in the Assessment of Patients Awaiting Kidney Transplantation
Cardiovascular disease (for example, heart attack, stroke, heart failure) is the commonest complication of kidney failure. Kidney transplantation reduces cardiovascular risk but cardiovascular disease remains the commonest cause…
- Trial name
- CRAFT-CTCA (NCT06234410)
- Testing
- Computed tomography coronary angiography (CTCA)
- Where
- 5 sites in United Kingdom
- Volunteers
- 332 people
- Sponsor
- University of Edinburgh
Impaired Health, Disease
The Lolland-Falster Health Study
The study is a epidemiological, cross-sectional study in a mainly rural area of Denmark in Denmark. Life expectancy is shorter, morbidity is higher, and social problems more prevalent than in the urban areas of the country.
- Conditions
- Impaired Health, Disease, Wellbeing, Mental Disorders
- Trial name
- LOFUS (NCT02482896)
- Where
- Denmark
- Volunteers
- 25,000 people
- Sponsor
- Region Sjælland
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention II
As a multi-center, retrospective observation study in southern China, this study included the main study population of patients who underwent coronary angiography at 5 hospitals from Guangzhou, Shenzhen, Yangjiang, Maoming and…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT05050877
- Where
- China
- Volunteers
- 184,855 people
- Sponsor
- Guangdong Provincial People's Hospital
Coronary Artery Disease
Drug-Coated Balloon Versus Drug-eluting Stent Angioplasty for Treatment of Chronic Total Occlusion - The DCB-CTO Trial
Chronic total occlusion (CTO) remains one of the most challenging lesions in coronary artery disease management. Percutaneous coronary intervention using drug-eluting stents is currently a standard treatment approach; however…
- Trial name
- DCB-CTO (NCT07369765)
- Testing
- Drug-Eluting Stent Group, Drug Coated Balloon Group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Biruni University
Ischemic Heart Disease, Myocardial Ischemia
Quality of Life in Patients With Chronic Ischemic Heart Disease
This study will examine the health-related quality of life in patients being treated for chronic heart disease. Patients 18 years or older with chronic ischemic heart disease and left ventricular dysfunction enrolled in protocols…
- Trial name
- NCT00005671
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Coronary Artery Disease (CAD), Chronic Total Occlusion (CTO)
AGECTO Study: PCI vs. Optimal Medical Therapy for CTO in the Octogenarian Patients
The study compares an interventional strategy (PCI) with optimal medical therapy (OMT) in ultra-octogenarians with chronic total occlusions (CTO).
- Conditions
- Coronary Artery Disease (CAD), Chronic Total Occlusion (CTO), Percutaneous Coronary Intervention (PCI), Optimal Medical Therapy
- Trial name
- AGECTO (NCT07442526)
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Luigi Gonzaga Hospital
Coronary Occlusion
Comparative Study Between Intravascular Ultrasonography Guided and Angiography-guided Recanalization of Coronary Chronic Total Occlusions
Chronic total occlusion is defined as thrombolysis in myocardial infarction (TIMI) flow grade 0 with an estimated duration of at least 3 months.
- Trial name
- NCT03159650
- Testing
- intravascular ultrasonography
- Volunteers
- 80 people
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2, Coronary Disease
A Study Comparing Standard Care for Diabetes to Case-managed Care for Diabetes in Patients With Coronary Artery Disease
The purpose of this study is to compare two ways to treat patients with Type 2 Diabetes, Standard Care or Case-Managed Care. In-Patient Standard Care is guided by the assigned cardiologist and Out-Patient Standard Care by the…
- Trial name
- NCT00248352
- Testing
- Consultation with Endocrinologist, Counseling from Dietician, Counseling from Diabetes Educator
- Where
- Canada
- Volunteers
- 169 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Artery Disease
Evaluation Rehabilitation on Glycometabolic State in Non-Diabetic Coronary Artery Disease (CAD) Patients
The purpose of this study is to evaluate the effects of an intensive Cardiac rehabilitation program on glucose metabolism of non-diabetic coronary artery disease patients.
- Trial name
- NCT00917930
- Testing
- physical training
- Sponsor
- IRCCS San Raffaele