Clinical trials: Chronic Postsurgical Pain
Chronic Postsurgical Pain, Chronic Post-surgical Pain
Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL)
Chronic postsurgical pain is a health problem with a great societal impact: approximately 20% of all children and adolescents undergoing surgery will develop chronic pain.
- Conditions
- Chronic Postsurgical Pain, Chronic Post-surgical Pain, Chronic Postoperative Pain, Chronic Post-operative Pain
- Trial name
- NCT06638437
- Testing
- Cognitive-behavioral therapy
- Where
- 3 sites in Spain
- Volunteers
- 125 people
- Sponsor
- University Rovira i Virgili
Chronic Pain, Postoperative, Quality of Life
Quality of Life and Pain After Appendectomy in Children
Acute appendicitis is one of the most common emergency general surgical conditions worldwide and represents the leading cause of emergency abdominal surgery in children.
- Conditions
- Chronic Pain, Postoperative, Quality of Life, Functional Ability, Appendectomy
- Trial name
- CAPA-Peds (NCT07629362)
- Where
- Turkey (Türkiye)
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Pain, Postoperative, Pain
Improved Rehabilitation After Spinal Surgery in Adolescents
Impact of the OFA technique on postoperative recovery from adolescent spine surgery and the incidence of chronic postoperative pain.
- Conditions
- Pain, Postoperative, Pain, Scoliosis, Spinal Fusion
- Trial name
- NCT04183049
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Pain, Postoperative, Chronic Pain Syndrome
Prevalence of Pain in the Departments of Surgery and Oncoematology of a Children's Hospital
Six years after, the authors will conduct the same analysis to check if there have been any improvements in the management of analgesic therapy after the measures taken according to the results of the previous study conducted in…
- Trial name
- NCT04209764
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Giuliano Marchetti
Chronic Post-surgical Pain
Pilot Study Evaluating Neuro-Imaging Correlates of Epigenetic Finding in Prediction of Chronic Postsurgical Pain
This pilot research study is being performed to learn more about pain and look at how pain changes brain chemistry and function. The research team would like to learn new information to better control chronic pain after surgery.
- Trial name
- NCT04681183
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Juvenile; Scoliosis, Scoliosis Idiopathic
Studying Melatonin and Recovery in Teens
The goal of this feasibility clinical trial is to learn if melatonin can help teens having major musculoskeletal surgery by promoting healthy sleep.
- Conditions
- Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital
- Trial name
- SurgerySMART (NCT06093477)
- Testing
- Fast-Dissolve Melatonin Pill
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Chronic Pain, Postsurgical Pain
Safety, Tolerability, Effectiveness, and Pharmacokinetic Data in Opioid-experienced Children
The purpose of this study was to assess the safety and pharmacokinetics (single- and multiple-dose) of oxymorphone ER for the relief of moderate to severe pain in pediatric participants ages 7 - ≤17 years old requiring a…
- Trial name
- NCT04681027
- Testing
- Oxymorphone hydrochloride (HCl)
- Where
- 5 sites in United States
- Volunteers
- 15 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Chronic Post Operative Pain
Prevalence and Risk Factors for Postsurgical Pain After the Open Reduction and Internal Fixation of Lower Limbs.
The objective of this study is to specify the demographic and medical factors that most likely constitute a risk of developing CPSP in the patients with lower limb.
- Trial name
- NCT06136663
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Chronic Tonsillitis, Tonsillectomy
Comparison of Cold Dissection Technique and Needle Monopolar Electrocautery Tonsillectomy
Patients 13-years-or older who undergo tonsillectomy operation (without another additional surgery) will be enrolled in the study.
- Conditions
- Chronic Tonsillitis, Tonsillectomy, Tonsillar Hypertrophy
- Trial name
- TONSIL (NCT02818647)
- Testing
- Tonsillectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Ilioinguinal Nerve Section, Pain Prevention
Prophylactic Ilioinguinal Neurectomy During Open Tension-Free Inguinal Hernia Repair
postoperative chronic inguinal pain is a common postoperative complication after open inguinal hernia repair. Chronic inguinal pain is a common complication following open inguinal hernia repair.
- Conditions
- Ilioinguinal Nerve Section, Pain Prevention, Hernioplasty
- Trial name
- NCT06327763
- Testing
- ilioinguinal nerve section
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Chronic, Infection
Pulpectomy of Primary Molars With Rotary Instrumentation Versus Manual Instrumentation
One of the major concerns in pediatric dentistry is premature loss of necrotic primary teeth which may cause a deleterious effect on the growth of the facial skeletal complex.
- Trial name
- NCT03964766
- Testing
- Rotary instrumentation, Hand instrumentation
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tonsillectomy, Tonsillitis Chronic
BiZact Tonsillectomy in the Pediatric Population
This study has been designed to evaluate how effective the Bizact tonsillectomy device is in reducing operating time and complications that occur after surgery.
- Conditions
- Tonsillectomy, Tonsillitis Chronic, Hemorrhage, Postoperative Pain
- Trial name
- NCT04725305
- Testing
- BiZact, Standard of care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Baylor College of Medicine
Post Operative Pain
Combined Supraclavicular Block and General Anesthesia in Pediatric Patients With Chronic Kidney Disease
compare the safety and efficacy of ultrasound-guided supraclavicular block in addition to general anesthesia in pediatric patients undergoing upper limb superficialization of arteriovenous fistula for hemodialysis.
- Trial name
- NCT05580094
- Testing
- general anesthesia only., general anesthesia plus supraclavicular block.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Pain, Postoperative
Epidemiology Study and Risk Factor Analysis on Chronic Post-surgical Pain After Video-assisted Thoracic Surgery
This study is a nationwide multi-center study to investigate the incidence and risk factors of chronic post-surgical pain (CPSP) after receiving video-assisted thoracic surgery (VATS).
- Trial name
- NCT05473728
- Where
- China
- Volunteers
- 886 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain, Chronic Pain
Chronic Postoperative Pain After Laparoendoscopic Groin Hernia Repair
The study attempts to quantify the relative risks for chronic postoperative inguinal pain (CPIP) depending on different combinations of mesh and mesh fixation.
- Trial name
- NCT04838028
- Testing
- TEP, TAPP, Other or unspecified laparoendoscopic groin hernia repair
- Volunteers
- 15,360 people
- Sponsor
- Karolinska Institutet
Chronic Postoperative Pain, Pediatric ALL
Chronic Postsurgical Pediatric Pain. Evaluation Risk Factors to Develop Chronic Postsurgical Pain in Children and Adolescents Undergoing Surgery in a First Level Hospital
Chronic postsurgical pain had number of prevalence on 20%. Its derivates from risk factors, but recent research provide new potential risk factors to develop chronic postsurgical pediatric pain.
- Trial name
- NCT04735211
- Testing
- Surgery
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Guillermo Ceniza Bordallo
Pain, Postoperative, Hernia, Inguinal
Surgical Pain After Inguinal Hernia Repair (SPAIHR)
The purpose of this study is to test whether pregabalin added to the standard of care with dosing starting preoperatively and continuing for 1 week post surgery will decrease the intensity of acute post-operative pain following…
- Trial name
- NCT00551135
- Testing
- Pregabalin
- Where
- 42 sites in United States, Australia and 4 more
- Volunteers
- 425 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Neuropathic Pain, Chronic Pain
Analgesic Effectiveness of Capsaicin 8% Cutaneous Patch in Children
This study concerns children aged to 12 to 17-years with local chronic neuropathic pain after trauma or surgery. It is a multicentric randomized controlled superiority trial in parallel arms : experimental arm: Capsaicin 8%…
- Trial name
- CAPSAPED (NCT05997979)
- Testing
- Capsaicin 8% patch, Hydrocolloid dressing
- Where
- 10 sites in France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Chronic Post-operative Pain
Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery
Chronic postoperative pain (CPOP) after video-assisted thoracic surgery (VATS) is severe because it results from lesions at multiple levels: incisions, pulmonary or nerve contusions.
- Trial name
- EVADRAINS (NCT07108582)
- Testing
- no NSAID, protocol for administering NSAIDs already used in routine care
- Volunteers
- 270 people
- Sponsor
- University Hospital, Strasbourg, France
Cerebral Palsy, Hip Dysplasia
Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT06189781
- Testing
- Ropivacaine injection, Bupivacaine, lidocaine, ropivacaine
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles